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68 results for “in vitro Analysis”
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Research ArticleOpen accessIn the abstractDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Activities of Selenium-Enriched Polysaccharides from Epimedium and Isatis IndigoticaRui Zhang, Jin Li, Jiajia ZhouThis study aims to investigate the effects of selenium modification on polysaccharides derived from two traditional Chinese medicinal herbs-Epimedium (Yinyanghuo) and Isatis root (Banlangen)-in enhancing immune function and antioxidant activity. The purpose is to explore the relationship between structure and function, providing a theoretical basis for the development of efficient plant-based functional antioxidants. Polysaccharides were extracted using an optimized enzymatic … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Feb 2026 · 1,933 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant Activity, Anti-Inflammatory and Analgesic Effects of Caralluma europaea (Eddaghmouss) in MiceAaziz Kebbou, Mehdi Ait Laaradia, Sara Oufquir et al.The aim of the current study is to evaluate the anti-inflammatory, antioxidant and analgesic properties of ethanolic (100 and 200 mg/kg, p.o.) and ethyl acetate extracts (100 and 200 mg/kg, p.o.) of Caralluma europaea. Formalin-induced paw licking test, Acetic Acid induced Writhing Test and Hot-PlateTest were used to assess the analgesic activity. Xylene-induced ear edema test was used to evaluate … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 24 Dec 2019 · 7,598 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vitro Immunomodulatory and Cytotoxic Potentials of Faloak (Sterculia quadrifida R.Br.) BarkTriana Hertiani, Purwantiningsih, Aji Winanta et al.Faloak (Sterculia quadrifida R.Br., Sterculiaceae) is an Indonesia indigenous plant widely used as a traditional remedy for various health complaints. This study aimed to explore the immunomodulatory and cytotoxicity potentials of Faloak bark by using in vitro techniques. Barks was extracted using water, ethanol and ethanol: water (1:1) separately. Colorimetric analysis was used for the determination of the total phenolic … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 6 Nov 2019 · 8,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlant Growth Promoting Activity of Actinomycetes Isolated from Soybean RhizosphereAris Tri Wahyudi, Jepri Agung Priyanto, Resti Afrista et al.Plant Growth Promoting Rhizobacteria (PGPR) is considered as the biological agent for improving plant growth. One Group of PGPR that have an important role in growth promoting of plant is Actinomycetes. The objective of this study was to isolate and screen Actinomycetes isolated from soybean rhizosphere as growth promoter of soybean in vitro. Fifty-three Actinomycetes isolates have successfully been isolated … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 5 Jan 2019 · 14,604 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Synergistic Effects of Agitation on the Interaction Between Nanoparticles of Polyethylene and Benzophenone in Microalgae Tetraselmis sp.Rafaela Luiza Dias Da Cunha, Camyla Lais Costa Leal, Lycia Brito-GitiranaAebi, H. (1984). Catalase in Vitro. In Methods in Enzymology (1st ed., Vol. 105, pp. 121–126). Academic Press. https://doi.org/10.1016/s0076-6879(84)05016-3 Bannister, J. V., & Calabrese, L. (1987). Assays for Superoxide Dismutase. Methods of Biochemical Analysis, 32, 279–312. https://doi.org/10.1002/9780470110539.ch5 Camacho, F. G., Gómez, A. C., Sobczuk, T. M., & Grima, E. M. (2000). Effects of Mechanical and Hydrodynamic Stress in Agitated, Sparged … …American Journal of Environmental Sciences, Vol. 19, Issue 5 · 28 May 2024 · 4,816 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolite Profiles of Arsenic Tolerant Plants Regenerated from Stem Calli of Andrographis paniculata (Burm.f.) Nees using HPLC and 1D 1H NMRJ. Vijayakumar, P. Ponmanickam, P. Samuel et al.In vitro culture provide a suitable condition for regeneration of arsenic tolerant plants from stem calli of Andrographis paniculata (Burm.f.) Nees. The regenerated plants could be valuable material applicable to soil remediation. In vitro culture of stem explants on MS basal salts, 3.0% sucrose, 0.8% agar medium fortified with various concentrations of As2O3 (0.0-9.0 µM) along with NAA (3.5 mg … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 27 Oct 2017 · 7,865 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessIn the abstractHybrid Ceramo-Polymeric Nanocomposite for Biomimetic Scaffolds Design and PreparationRaffaella Aversa, Relly Victoria V. Petrescu, Roberto Sorrentino et al.Biomimetics, biomechanics and tissue engineering are three multidisciplinary fields that have been contemplated in this research to attain the objective of improving prosthetic implants reliability. Since testing and mathematical methods are closely interlaced, a promising approach seemed to be the combination of in vitro and in vivo experiments with computer simulations (in silico). An innovative biomimetics and biomechanics approach and … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 30 Nov 2016 · 8,269 accessesView PDFCite