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2,585 articles for “design”
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Research ArticleOpen accessEvery word in the titleIn-silico Rational Protein Engineering and Design Approach to Improve Thermostability of a Haloalkane Dehalogenase EnzymeRaghunath Satpathy, V. Badireenath Konkimalla, Jagnyeswar RathaThermostability of enzymes is a major prerequisite for use in industrial enzymology. There are as such no simple general principles for achieving thermostability in case of enzymes as many factors are required to fulfil for different enzymes. The present study describes computational methods to design thermostable haloalkane dehalogenase enzyme using the crystal structure available Protein Data Bank (PDB ID: 1EDE). … …Current Research in Bioinformatics, Vol. 4, Issue 2 · 13 Oct 2015 · 8,285 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAdaptive Superiority and Noninferiority Trial Design with Paired Binary DataMark Chang, Jing WangNon-inferiority of a diagnostic test to the standard is a common issue in medical research. For instance, we may be interested in determining if a new diagnostic test is noninferior to the standard reference test because the new test might be inexpensive to the extent that some small inferior margin in sensitivity or specificity may be acceptable. Noninferiority trials are … …Current Research in Biostatistics, Vol. 5, Issue 2 · 7 Sep 2015 · 8,239 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBig Data in Design and Manufacturing EngineeringLidong Wang, Cheryl Ann AlexanderBig Data helps facilitate information visibility and process automation in design and manufacturing engineering. It also helps analyze trends through analytics and predict inventory, manufacturing output and equipment lifespan and cycles, etc. This paper introduces Big Data, its characteristics and a number of issues of Big Data in design and manufacturing engineering. These issues include design and manufacturing data, Big … …American Journal of Engineering and Applied Sciences, Vol. 8, Issue 2 · 25 Jun 2015 · 8,734 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleTotal Occlusal Convergence and Margin Design in Relation to Survival of Glass-Ceramic Crowns: A ReviewJanine Tiu, J. Neil Waddell, Basil Al-Amleh, Michael V. SwainThis review aims to report on preparation geometry parameters and their relation to crown failures in complete glass-ceramic clinical studies. A review of the literature was conducted in MEDLINE/PubMed with an additional manual search. The articles were screened through an inclusion and exclusion criteria and information regarding the Total Occlusal Convergence (TOC) angle and margin design was extracted along with … …Current Research in Dentistry, Vol. 5, Issue 2 · 1 Jun 2015 · 8,620 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePossibility and Evidence-Based Reliability Analysis and Design OptimizationHong-Zhong Huang, Liping He, Yu Liu et al.Engineering design under uncertainty has gained considerable attention in recent years. A great multitude of new design optimization methodologies and reliability analysis approaches are put forth with the aim of accommodating various uncertainties. Uncertainties in practical engineering applications are commonly classified into two categories, i.e., aleatory uncertainty and epistemic uncertainty. Aleatory uncertainty arises because of unpredictable variation in the performance … …American Journal of Engineering and Applied Sciences, Vol. 6, Issue 1 · 26 Mar 2013 · 7,669 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDesign of Object-Oriented Debugger Model by Using Unified Modeling LanguageNor Fazlida Mohd Sani, Noor Afiza Mohd Ariffin, Rodziah AtanDebugging on computer program is a complex cognitive activity. Although it is complex, it’s still one of the popular issues in computer programming task. It is a difficult task, which is to understand what the error is and how to solve such error? In computer programming the difficulty is to understand the Object-Oriented programming concept together with the programming logic. … …Journal of Computer Science, Vol. 9, Issue 1 · 22 Jan 2013 · 7,173 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Influence of Clients’ Qualities on Green Design Performance of Building Projects in Malaysia-Descriptive StudyMohamed S. Elforgani, Ismail RahmatProblem statement: In the construction industry, success of building projects greatly depends on the client’s performance. The performance of clients is crucial since decisions made will influence the overall project performance. Typically, clients are represented by managerial and technical representatives during the design process. They play major roles in conveying required information to the design team regarding their future project. … …American Journal of Applied Sciences, Vol. 9, Issue 10 · 18 Aug 2012 · 7,699 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleFramework for Managing the Very Large Scale Integration Design ProcessSabah Al-Fedaghi, Eman Al-DwaisanProblem statement: The VLSI design cycle was described in terms of successive states and substages; it starts with system specification and ends with packaging. At the next descriptive level, currently known methodologies (e.g., flowchart based, object-oriented based) lack a global conceptual representation suitable for managing the VLSI design process. Technical details were intermixed with tool-dependent and implementation issues such as … …American Journal of Applied Sciences, Vol. 9, Issue 2 · 13 Dec 2011 · 7,497 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDesign Strategies to Persuasive Learning for Promoting Sustainable Practices in Paddy FarmingZakirah Othman, Amran MuhammadProblem statement: Public awareness of sustainable agriculture is low, especially in organic paddy practices. As alternative, introducing Information and Communication Technology (ICT) application like electronic learning is an effective way to educate and promote the young generation to appreciate sustainable agriculture. Therefore, the main objective of this study is to discuss a design of a prototype of persuasive learning in … …American Journal of Economics and Business Administration, Vol. 3, Issue 1 · 31 Jan 2011 · 7,404 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRational Mix Design Approach for High Strength Concrete Using Sand with very High Fineness ModulusKwan Wai Hoe, Mahyuddin RamliProblem statement: Production of concrete is always deal with inconsistency. Sources of variation like materials from different geographical basis, mix design method, fineness of aggregates and so on will attribute to different level of achievement of the concrete. Even though researcher had verified that higher fineness modulus of sand would yield better performance for the concrete, but so far there … …American Journal of Applied Sciences, Vol. 7, Issue 12 · 31 Dec 2010 · 8,222 accessesView PDFCite