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35 articles for “RFLP”
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Research ArticleOpen accessIn the abstractMeasurement of the Gene Expression and Polymorphisms of c-myc and p53 Genes in HBV Infected PatientsFayed Koutb, Salah Abdel-Rahman, Ehab Hassouna, Amany HaggagThis study explained the c-myc and p53 gene expression and polymorphisms in chronic (40), cirrhosis (30) and Hepatocellular Carcinoma, (HCC) (30) patients related to Hepatitis B Virus (HBV) infection and healthy control (50) in Egypt. Where, c-myc (intron 8) and p53 (codon 72) gene expression and polymorphisms were determined using qRT-PCR and PCR-RFLP techniques. The results showed that c-myc gene … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 22 Feb 2021 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetics Polymorphisms of INHA in Local Goat Populations in South-West Sulawesi Region of IndonesiaMuhammad Ihsan Andi Dagong, Sri Rachma Aprilita Bugiwati, Lellah Rahim, Nurul PurnomoInhibin subunit alpha (INHA) is one important gene that control reproductive characteristics of animal. The aim of this research was to identify the genetic diversity of INHA gene of Kacang and Peranakan Etawa (PE) goat as local goat breed which were maintained by farmers at goat development centers in Sulawesi region, Indonesia. DNA samples were collected from 137 heads Kacang … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 12 Mar 2020 · 7,273 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Receptor Activator of Nuclear Factor Kappa B (RANK) and Receptor Activator of Nuclear Factor Kappa B Ligand (RANKL) in Osteoporosis Risk: Gene Polymorphism and Soluble RANKL Level in Indonesia Post-Menopausal WomenLuluk Yunaini, Dwi Anita Suryandari, Linda Kusdhany et al.Hormonal changes in postmenopausal women may increase osteoclastogenesis that can lead to increased risk of osteoporosis. Receptor Activator of Nuclear factor Kappa B (RANK) and Receptor Activator of Nuclear factor Kappa B Ligand (RANKL) have an important role in osteoclastogenesis that involve in the regulation of bone resorption. In this study, we analyzed the Single Nucleotide Polymorphism (SNPs) within the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 3 · 27 Sep 2018 · 8,180 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssociation of High-Affinity FcεRI-β intron 2 for IgE Gene Polymorphism and Atopic Diseases in an Algerian PopulationDahbia Ines Dahmani, Ikhlass Haj Salem, Jamila Chakir et al.Atopy is characterized by the production of a high level of IgE in response to common allergens. We examined the RsaI-in2 polymorphism of the FcεRI-β gene and its association with atopic asthma and comorbidity. The study population included 77 atopic asthmatics and 77 non-atopic, non-allergic and non-asthmatic controls. Atopic asthma was confirmed by the skin prick test and by IgE … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 1 Nov 2017 · 7,444 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Single and Combined Effect of MC4R and GH Genes on Productive Traits of PigsLyubov Getmantseva, Maria Leonova, Aleksander Usatov et al.The aim of our work is to identify the single and combined effect of MC4R and GH polymorphism genes on growth and reproduction traits of pigs. The study was carried out on 204 crossbred F1 females (♀Landrace х ♂Large White) of the Breeding Farm in Russia. The analyzed productive traits were: The number of Days to 100-kg (Days to 100 … …American Journal of Agricultural and Biological Sciences, Vol. 12, Issue 1 · 18 Jan 2017 · 8,115 accessesView PDFCite
Research ArticleOpen accessIn the abstractFrequency of Single Nucleotide Polymorphisms of the SLCO1B1 Gene in Slavic Population of Central EuropeMichaela Mikulová, Veronika Kramarova, Ján ChandogaThe organic anion transporting polypeptide 1B1 (encoded by SLCO1B1 gene) is involved in the active cellular influx of diverse endogenous compounds and several drugs, such as HMG-CoA reductase inhibitors (statins). Two common polymorphisms c.388A>G and c.521T>C in SLCO1B1 alter transport activity of this transporter and play an important role in the pharmaceutical response to many drugs. The aim of our … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 11 Dec 2016 · 7,308 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy the Impact of T-helper 1 Cytokine (TNF-α) Polymorphisms on Susceptibility/Resistance to Brucellosis in Makkah RegionAlaa B. Ismael, Adil Mergani, Salama A-H Mostafa, Abdelmoneim M. SalimPolymorphisms in the regulatory regions of cytokine genes may not only increase susceptibility to some infectious diseases but also affect the course and prognosis of the disease. TNF-α is considered an important Th1 cytokines that plays critical roles in control of Brucella infection and in macrophage activation. In this study, we are going to analyze the relationship of two polymorphisms … …American Journal of Infectious Diseases, Vol. 12, Issue 3 · 9 Aug 2016 · 7,119 accessesView PDFCite
Research ArticleOpen accessIn the abstractLEUKOTRIENE C4 SYNTHASE AND LEUKOTRIENE RECEPTOR-1 GENES POLYMORPHISM AMONG ATOPIC ASTHMATIC PATIENTSHeba M. Kadry, Amal H. Atta, Mostafa K. Sultan, Nagwa A. El-BazAsthma is a complex polygenic disease in which Cysteinyl Leukotrienes (Cys-LTs) are a potential risk factors causing airway inflammation and remodeling, which are characteristics of asthma. The polymorphisms in the leukotriene C4 synthase -444A/C and cysteinyl leukotriene receptor1 927 T/C genes has been implicated in susceptibility to asthma. The objective of this study was to analyse two different polymorphisms, LTC4S-444 … …American Journal of Immunology, Vol. 10, Issue 2 · 5 May 2014 · 7,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTS OF MELANOCORTIN-4 RECEPTOR GENE ON GROWTH AND MEAT TRAITS IN PIGS RAISED IN RUSSIAA. Klimenko, A. Usatov, Lyubov Getmantseva et al.The Melanocortin-4 Receptor (MC4R), a G-protein coupled receptor, is implicated in mediating the effect of leptin on food intake and energy balance. A previous candidate gene study reported an association between an MC4R polymorphism (Asp298Asn) and growth and meat productive traits of pigs. The aim of this work was to determine frequencies of the MC4R/Taq I genotypes and alleles in … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 2 · 11 Feb 2014 · 7,608 accessesView PDFCite
Research ArticleOpen accessIn the abstractG-2548A Leptin Promoter and Q223R Leptin Receptor Polymorphisms in Obese Mexican SubjectsP. Carrillo-Vazquez Jonathan, Lopez-Alcantar Jeronimo, Chimal-Vega Brenda et al.Leptin interaction with its receptor in the hypothalamus stimulates a specific signaling cascade that results in the synthesis of anorexigenic and orexigenic peptides in order to regulate food intake and energy expenditure. Many polymorphisms in leptin (lep) and leptin receptor (lepr) genes have been associated with body weight. In particular, G-2548A in the lep promoter and Q223R in lepr variants … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 1 · 12 Feb 2013 · 8,641 accessesView PDFCite