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59 results for “Peripheral Blood”
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Research ArticleOpen accessIn the abstractFrequencies of the C1236T, G2677T/A, and C3435T Polymorphisms of the MDR1 Gene and their Haplotypes in UzbekistanS. B. Nurmatova, A. A. Abdurakhimov, O. S. Charishnikova et al.P-glycoprotein (P-gp) is encoded by the MDR1 gene and is involved in the pharmacokinetics of drugs. The best-known MDR1 gene polymorphisms are 1236C>T, 3435C>T, and 2677G>T/A, which are associated with protein folding, changes in mRNA levels, and drug pharmacokinetics. The aim of this study was to identify the frequency of distribution of functional polymorphisms C1236T, C3435T, G2677T/A of the MDR1 … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Immune Complexes in Essential HypertensionIvan MilosevicEssential hypertension is a rise of arterial blood pressure whose etiology is unknown. Immune complexes are complexes created by the binding of an antibody to the antigen. They are also called circulating immune complexes because of its precipitation in peripheral blood vessels, commonly on the places of their bifurcation and the places of higher blood pressure (glomerules of kidney or … …American Journal of Immunology, Vol. 18, Issue 1 · 2 Nov 2022 · 9,979 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntravenous Injection of Umbilical Cord-Derived Mesenchymal Stem Cells Improved Regeneration of Rat Liver after 2AAF/CCl4-Induced InjuryIsabella Kurnia Liem, Reni Oktavina, Zakiyah et al.The effectivity of Mesenchymal Stem Cell (MSC) therapy for chronic liver injury is still questioned due to its possibility to have a pro-fibrotic effects. Other consideration is the preferably peripheral Intravenous (IV) route of application rather than direct to the target organ, such as portal vein or splenic vein, since the most of MSC will be trapped in the lung … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 10 Jun 2021 · 6,784 accessesView PDFCite
Research ArticleOpen accessIn the abstractNCCRP-1 Might Not be a Marker of so Called NCC Cells in Common Carp (Cyprinus carpio) LeukocytesMazal Shimon-Hophy, Avi Jacob, Ramy R. AvtalionThe purpose of this study was to verify whether NCCRP-1 is a marker of a unique type of cells in teleost, so-called NCC, or an ubiquitin, like in cytotoxic cells. Therefore, common carp peripheral blood leukocytes were isolated and tested for the binding of fluorescent NCCRP-1 antibody to stained MAIT, γδ T and T cells following stress treatments. The results … …American Journal of Immunology, Vol. 16, Issue 1 · 26 Mar 2020 · 7,757 accessesView PDFCite
Research ArticleOpen accessIn the abstractSome Aspects of the Human Body’s HydraulicsRelly Victoria Virgil Petrescu, Raffaella Aversa, Antonio Apicella, Florian Ion Tiberiu PetrescuThis paper presents some aspects related to the human body’s hydraulics in the desire to make readers aware of how to maintain all the blood vessels of the human body in order to maintain the entire healthy, functional, young, vigorous circulatory system for a while the longest possible. The problem is complex because it has to be viewed from all … …OnLine Journal of Biological Sciences, Vol. 19, Issue 3 · 9 Aug 2019 · 7,180 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvolvement of the α/β Isoform of p38 MAP Kinase in Chemotactic Responses of Human Eosinophils to Eotaxin (CCL11) and RANTES (CCL5)Anwar M Hasan, Gordon DentEosinophils are the principal effector cells for allergic inflammation in a variety of diseases, in which they contribute to tissue damage and remodelling processes via the secretion of cytotoxic granular proteins and cytokines. The intracellular mechanisms that control the activation, recruitment and survival of eosinophils are fundamental in understanding these disease processes. Phosphoinositide 3-kinase (PI3K) has been shown previously to … …American Journal of Immunology, Vol. 13, Issue 4 · 26 Oct 2017 · 7,946 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim SubpopulationManar M. IsmailGenerally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory … …American Journal of Immunology, Vol. 13, Issue 3 · 30 Aug 2017 · 7,794 accessesView PDFCite
Research ArticleOpen accessIn the abstractHumoral and Cellular Effects of Stress-An Extensive Model SystemMazal Shimon-Hophy, Ramy R. AvtalionThe influence of stress on the immune system of the common carp (Cyprinus carpio) was studied by measuring leukocytes levels using flow cytometry and mRNA immune components by real time qPCR. Acute and chronic oxidative stresses were generated by different regimes of exposure of carp to environmental air. In acute stress, induced by single air exposure, the pro-inflammatory cytokines (IL1β, … …American Journal of Immunology, Vol. 13, Issue 2 · 18 Apr 2017 · 6,728 accessesView PDFCite
InvestigationOpen accessIn the abstractMeaning of the Oral Hygiene in Children, Due to Atherosclerosis GenerationAnna Wójtowicz-Bujak, Andrzej WolskiResearch focused on association between periodontal diseases and atherosclerosis has been substantial in recent years. It is now well known that chronic inflammation plays an important role in initiation and evolution of atherosclerosis. The bacterial plaque is a key pathology leading to periodontal inflammation. As reported by other authors, bacteria causing periodontal disease were found within the carotid arteries in … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 7 Nov 2015 · 7,205 accessesView PDFCite