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158 articles for “Mice”
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Research ArticleOpen accessEvery word in the titleImmunomodulatory and Antioxidant Effects of Stachys Japonica Miq. Ethanol Extract on Cyclophosphamide-Induced Immunosuppressed Mice and its Phytochemical CompositionXueping Jiang, Jianglong He, Yanjun Chen, Fang WangStachys japonica Miq. is an edible wild botanical drug and a traditional medicine in China. This study focused on examining the phytochemical profile and antioxidant properties of the ethanol extract of S. japonica Miq (SJEE) in vitro, as well as its immunomodulatory and antioxidant activities in cyclophosphamide (Cy)-induced immunosuppressed mice. The SJEE was analysed by UPLC-HRMS/MS. 36 Polyphenols, including flavonoids, … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 13 Apr 2026 · 1,449 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Static Magnetic Field Exposure in Obese Mice Induced by High Fat Diet: Its Effect on T-Box15 Gene and Uncoupling Protein 1 ExpressionWidia Bela Oktaviani, Puji Sari, Luluk Yunaini et al.Increased Ca2+ cytosolic concentration caused by Static Magnetic Field (SMF) exposure modulates Tbx15 protein and Ucp1 gene interaction that is involved in the thermogenesis browning process of white adipose tissue. Activation of Tbx15 as a transcription factor that regulates the expression of the Uncoupling protein 1 (Ucp1) gene induced by SMF exposure in adipose tissue converts excess accumulated fat into … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 23 Jan 2024 · 4,521 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Purified Tick Saliva Toxins on Various Bio-Molecules in Blood Serum, Liver and Muscles of Albino MiceNidhi Yadav, Ravi Kant UpadhyayIn the present study, salivary toxins from Rhipicephalus microplus were isolated and purified on a Sepharose CL 6B 200 gel column at a constant flow rate with regular fractions of 5 mL/min. Pooled fractions were lyophilized and LD50 was then determined in albino mice. The LD50 value of the protein toxin of Rhipicephalus microplus was found 36.11 mg/kg body weight … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 1 · 30 Dec 2023 · 5,354 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSelenium Enriched Peanut Protein Alleviates Alcohol-Induced Liver Damage in Mice by Modulating the Composition of the Gut MicrobiotaLin Gao, Jiawei Yuan, Yuhuan Cheng et al.Alcohol Use Disorder (AUD) is one of leading external causes of mortality. Selenium-enriched Peanut Protein (SePP) is a type of Se compound present in Se-enriched plants. Our previous studies showed that SePP possesses potential therapeutic properties and could alleviate alcohol-induced AML-12 cytotoxicity. It spurred us to determine the underlying mechanisms and roles of SePP on gut microbiota. Here, ICR mice … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 23 Dec 2021 · 6,230 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImpact of Euphorbia helioscopia Extract Administration on Diabetes Induced by Alloxan in MiceDoha Mohammad Beltagy, Amira Mohammed Beltagy, Mohammad Ramadan et al.Diabetes describes metabolic disorder with hyperglycemia and neurotic changes. This work aimed to evaluate the protective effect of total ethanolic extract of Euphorbia helioscopia grown in Egypt against pancreas and brain injuries in diabetic mice induced by alloxan. This work was carried out on 60 mice divided into four groups. Control Group (G1) included healthy normal mice that did not … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 19 Oct 2020 · 6,406 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleChanges in Prothrombin Time and Platelet Parameters of Mice Treated with Vitamins C and EHongwei Li, Jing Cheng, Wei Wang et al.This study aims to elucidate the influence of supplementation with different doses of Vitamin C (VC) and Vitamin E (VE) on Prothrombin Time (PT) in mice; forty eight mice are randomly divided into six treatment groups, which are fed different dose VC and VE except for control Check (CK) for eight weeks. Blood samples are obtained from the mouse canthus … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 15 Apr 2020 · 7,087 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssessment of the Annona muricata Leaf Ethanol Extract Effect on The Diameter of Pancreatic Islets in Alloxan-Induced MiceSyafira N. Dewi, Supri I. Handayani, Marini Stephanie et al.Diabetes mellitus is one of a non-communicable disease whose prevalence continues to increase from year to year in both developed and developing countries. In Indonesia, it is estimated that 12 million people aged ≥15 years old had diabetes mellitus in 2013. Treatment of diabetes mellitus by using plant extract has been reported to have good results. One of the plants … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 9 Mar 2020 · 8,061 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnticonvulsant Activity of Hydroalcoholic Phoenix dactylifera Fruit Extract and Pimpinella anisum Oil in MiceSameh Mohamed Mostafa EL-Nabtity, Ahmed Shaban Abdelaziz, Manar Salah Moselhi, Mario GiorgiEpilepsy is a group of long-term neurological disorders characterized by epileptic seizures. The present study sought to investigate the anticonvulsant and neuroprotective Activity of Hydroalcoholic Phoenix dactylifera fruit extract (HAPD) and Pimpinella Anisum Oil (PAO) against Pentylenetetrazole (PTZ) and Maximal Electric Shock (MES) induced a seizure in mice. Mice groups were treated with HAPD1000 mg/kg, PAO 4 ml/kg. The onset … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 2 · 25 May 2019 · 7,590 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Pre-Slaughter Autophagic Status on Postmortem Proteolysis in Skeletal Muscle of MiceTomonori Nakanishi, Miho Yamashita, Naoto Nishimoto et al.Post mortem proteolysis is a key event during the aging process, where muscle converts to meat. However, its precise mechanism remains unclear. In this study, the effects of pre-slaughter autophagic status on post mortem proteolysis were investigated using mouse skeletal muscle. Mice were fasted for 14 h and administered with or without the autophagy inhibitor wortmannin, whereas control mice were … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 2 · 10 Jul 2017 · 7,988 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunologic Aspect of Mice (Mus musculus) Dental Caries Induced by Streptococcus mutansSri MurwaniDental caries (tooth decay), cavities or caries is a breakdown of teeth due to activities of bacteria acid producing in the presence of fermentable carbohydrates. The most responsible bacteria for dental cavities are Streptococcus mutans. Dental shape, saliva pH, normal flora, diets were suggested as predisposition factors for dental plaque and caries. The aim of this research was to study … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 28 Mar 2017 · 8,123 accessesView PDFCite