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241 articles for “Lipid”

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Research ArticleOpen accessEvery word in the titleEffects of Artemisinin-Based Combination Therapies on Lipids and Hepatorenal Circulating Indices in Guinea PigsAbaram Chesa Mankwe, Jonah Sydney Aprioku, Atuboyedia Wolfe ObianimeArtemisinin-based Combination Therapies (ACTs) are employed as first-line agents in malaria chemotherapy. In many malaria endemic areas, ACTs are frequently abused partly due to resistance, poor drug control and inadequate health facilities. This study investigated the effects of prolong administration of Artesunate-Sulfadoxine-Pyrimethamine (ATS-SP), Artesunate-Amodiaquine (ATS-Amod) and Artemether-Lumefantrine (ATM-Lum) on plasma levels of biochemical parameters (AST, ALT, ALP, urea and creatinine) … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 2 · 3 Apr 2017 · 7,282 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIdentification of Pseudozyma hubeiensis Y10BS025 as a Potent Producer of Glycolipid Biosurfactant Mannosylerythritol lipidsMartha Sari, Atit Kanti, I. Made Artika, Wien KusharyotoMannosylerythritol Lipids (MEL’s) are glycolipid biosurfactants that contain 4-O-β-D-mannopyranosyl-meso-erythritol as a hydrophilic moiety and fatty acids as a hydrophobic moiety. MEL’s are abundantly produced by several kinds of microorganism and are one of the most promising biosurfactants currently known. The search for a novel endogenous producer of MEL’s was undertaken based on the available collection of the yeast strains from … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 8,095 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleCirculating Immune Complexes as an Important Link between Inflammation and Lipid Alterations in AtherosclerosisAnastasia Vladimirovna Poznyak, Nikolay Alexandrovich Orekhov, Vasily Nikolaevich Sukhorukov et al.This review article rigorously investigates the emerging facets of atherosclerosis pathogenesis through an exhaustive examination of the existing data on the intricate interplay between lipid metabolism disorders and inflammation. A primary objective of this study is to thoroughly explore the role of Circulating Immune Complexes (CIC) as a pivotal indicator of this multifaceted interaction. The focus of this review centers … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 14 Aug 2024 · 3,926 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleSIRT1 Controls Lipid Metabolism Under Physiological and Pathological Conditions: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Ludmila Viktorovna Nedosugova, Victoria Alexandrovna Khotina et al.This comprehensive review examines the multifaceted role of Sirtuin 1 (SIRT1) in cellular metabolism and energy regulation, with a particular focus on its involvement in lipid metabolism and glucose regulation. Additionally, SIRT1's impact on several pathologies, including osteoarthritis, diabetes, and cardiovascular disease, is explored. Notably, this review sheds light on the unique contribution of SIRT1 in the development and progression … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 7 Jun 2024 · 4,739 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Adding Cellulose on Lipid Accumulation in Cellobiohydrolase and Delta-6 Desaturase Engineered Mucor circinelloides StrainsYao Zhang, Yanxia Wang et al.Despite microbial production of multifunctional gamma-linolenic acid (GLA) being an important and promising way, the high cost is still a major factor limiting industrial applications. Previously, we proposed a novel approach to promote the production of GLA from cellulose, a widely available and cheapest resource, by overexpression of the cellobiohydrolase (CBH2) and delta-6 desaturase (D6) in Mucor circinelloides. In the … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 13 Oct 2023 · 4,731 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,955 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImproved SDA Production in High Lipid Accumulating Strain of Mucor circinelloides WJ11 by Genetic ModificationJunhuan Yang, Md. Ahsanul Kabir Khan, Sergio López-García et al.Stearidonic Acid (SDA; 18:4, n-3) is a ω-3 polyunsaturated fatty acid which is nutritionally important and has pharmaceutical applications. Hence, scientists are trying to construct SDA producing oleaginous microorganisms by genetic modification. Two enzymes, Delta-6 Desaturase (D6D) and ω-3 desaturase catalyze the reactions to produce SDA from Linoleic Acid (LA; 18:2, n-6). But the key enzyme, ω-3 desaturase converts LA … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 23 Mar 2020 · 8,240 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Gold Nanoparticles on Serum Lipid Profilein Albino MiceAmmal Esmaeel Ibrahim, Taha Shawi Morad, Dhelal A Shabeeb, Shatha M HasanTriglycerides and lipoproteins are threat features for Cardio Heart Disease. The word “nano” is derived from the Greek word “nanos” which means slight and it is used as introduce for one billionth part (10-9). Conferring to American Society for Testing and Materials. Nanoparticles are those atoms which have two or more than two dimensions and are in the magnitude range … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 31 Oct 2018 · 7,367 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Dayak Onion (Eleutherine bulbosa (Mill.) Urb) on Uterine wall and Lipid Profiles of Ovariectomized RatAmalia Purnamasari, Anton BahtiarMenopause is a physiologic condition, in which women no longer experience menstruation. Decreased estrogen during and after menopause causes structural, physiological and biochemical changes that alter the health of women in general, both in organs and non-reproductive organs. Dayak onion contains eleuterinol, an naphtoqunone derivative that can be as SERM. Therefore, we evaluated the effects of dayak onions on lipid … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 23 Dec 2017 · 9,996 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleASCORBIC ACID FOLIIAR SPRAY COUNTERACTING EFFECT OF SALINITY ON GROWTH, NUTRIENTS CONCENTRATIONS, PHOTOSYNTHESIS, ANTIOXIDANT ACTIVITIES AND LIPID PEROXIDATION OF BEAN (PHASEULUS VULGARIS L.) CULTIVARSZeinab A. Salama, El-Zanaty A.A. Abou El-Nour, Mohamed M. El Fouly, Alaa A. GaafarA water culture experiment was carried out in the Department of Fertilization Technology at National Research Centre, Cairo, Egypt, to investigate the effect of Ascorbic Acid (AsA) foliar application and salinity stress (100 ppm and 100 mmoL NaCl) on growth, nutrients concentration and some biochemical parameters of two kidney bean (Phaseulus Vulgaris L.) cultivars. Salinity caused significant reduction in growth … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 3 · 16 May 2014 · 7,900 accessesView PDFCite