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91 articles for “Human Action”

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EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractDeterminants Factors of Agricultural Extension Services Performance and Impacts on Farmers' BehaviorMuh. Hatta Jamil, Amri Jahi, Muhammad Arsyad et al.Agricultural extension plays an important role in improving the quality of human resources, also it function as a learning process for the main actors so that farmer will be able to help and organize themselves in accessing market information, technology, capital and other resources. Problem that arise among stakeholders have been widely debated. Since then, determinant factor of Agricultural Extension … …American Journal of Agricultural and Biological Sciences, Vol. 12, Issue 1 · 2 Feb 2017 · 8,784 accessesView PDFCite
Research ArticleOpen accessIn the abstractCopper (I)-Nicotinate Promotes Gene Expression of CYPs that Produce M1 and Q1 in Aflatoxicosed RatsMohammed Salah, Laila Mostafa, Tahia H. Saleem et al.Aflatoxin-contaminated food poses a serious risk to both human and animal health. Copper (1)-nicotinate (Cu+-nicotinate) complex potentiated the prophylactic effect against chronic aflatoxicosis in the experimental animals through the synthesis of less toxic metabolites M1 and Q1 which are easily excreted in urine. To investigate the action of the safety Cu+-nicotinate complex on gene expression of Cytochrome 450 (CYP450) system, … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 28 Jan 2020 · 8,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractOne Can Slow Down the Aging through AntioxidantsRaffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuFree radicals are natural nanoparticles which are doing their part well defined in the human cell, but then they must be annihilated or eliminated to not destroy the cell or another part of our body. It has been shown that residual free radicals in the body are responsible for the aging. The role to annihilate them is ful-filled by the … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 8 Dec 2016 · 10,070 accessesView PDFCite
Research ArticleOpen accessIn the abstractEntrenching Inferences in Implicational and Illocutionary ConstructionsFrancisco José Ruiz de Mendoza IbáñezThe starting point for the present paper is the classification of constructions, understood as fixed pairings of form and meaning, into four levels of meaning representation, i.e., the argument-structure, implicational, illocutionary and discourse levels. The meaning part of constructions contains fixed and variable elements. In argument-structure constructions the fixed elements are generic and, as such, they are open to parameterization … …Journal of Social Sciences, Vol. 11, Issue 3 · 14 Aug 2015 · 8,199 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,158 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparedness in Implementing Action Plan for Reducing GHGs: The Case of Central JavaAgung SugiriThe Regional Action Plan for Reducing Greenhouse Gas Emissions (RAD-GRK) of Central Java Province 2020 was completed in 2012. This paper assesses the preparedness of the Central Java Provincial Government (CJPG) to implement the plan and identifies measures needed to ensure successful implementation based on the stakeholders' perceptions. In-depth interviews with key CJPG officials and a workshop with the extended … …American Journal of Environmental Sciences, Vol. 11, Issue 1 · 2 Apr 2015 · 8,097 accessesView PDFCite
Research ArticleOpen accessIn the abstractDUAL ROLES OF CANCER CELL-EXPRESSED IMMUNOGLOBULINS IN CANCER IMMUNOLOGYGregory Lee, Cheng-Yuan Huang, Suefay Liu et al.While the expression of immunoglobulins and T cell receptors on cancer cells has been well-established for decades, the potential roles and mechanisms of action of these cancerous antigen receptors have not been fully elucidated. A monoclonal antibody designated as RP215, which reacts specifically with the carbohydrate-associated epitope located on the heavy chain region of cancerous immunoglobulins and T cell receptors, … …American Journal of Immunology, Vol. 10, Issue 3 · 2 Oct 2014 · 7,870 accessesView PDFCite
EditorialOpen accessIn the abstractRECENT TRENDS AND CHALLENGES OF ENERGY EFFICIENT AND SUSTAINABLE BUILDINGSChiara BedonAccording to several studies (e.g., the Intergovernmental Panel on Climate Change (IPCC, 2014), the US Energy Information Administration (US EIA, 2014), warming of the climate system is unequivocal and mainly derives from greenhouse gas emissions due to human activities. Global Carbon Dioxide (CO2) emissions from fossil fuels, for example, are estimated to be 29% higher in 2035 than they were … …American Journal of Engineering and Applied Sciences, Vol. 7, Issue 3 · 11 Sep 2014 · 8,497 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Cloning and Heterologous Expression of Human Interferon Alpha2b GeneI. Made Artika, Yemima Budirahardja, Anna Lucia EkowatiHuman alpha Interferons (hIFNα) have been shown to have antiviral, antiproliferative and immunomodulatory activities. The human interferon alpha2b (hIFNα2b), is one of the human interferon alpha2 sub variants, naturally synthesized as a polypeptide of 188 amino acid residues, the first 23 residues of which represents a signal peptide. In the present study, the hIFNα2b gene was expressed after being fused … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,835 accessesView PDFCite