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52 articles for “Gene expression analysis”
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Research ArticleOpen accessIn the abstractEnhancement of Nutritional Quality of Wheat (Triticum aestivum) by Metabolic Engineering of Isoflavone PathwayAhmed Mohamed El-Shehawi, Abdelmegid Ibrahim Fahmi, Mona Mohamed Elseehy, Hesham Ahmed NagatyIsoflavones are large group of secondary metabolites produced in legumes such as soybeans. They have essential biological functions as nutraceutical and health functions for human. They are involved in plant resistance to biotic and abiotic stresses, symbiotic relationship with nitrogen-fixing organisms and plant competition (allelopathy). In this report, isoflavonoids were expressed in wheat (Triticum aestivum) via introducing the key enzymes … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractP53 Gene: Mutation and Immunohistochemical Analysis in Patients with Invasive Ductal Carcinoma of BreastShinjini Singh, Sandeep Kumar Rajput, Mritunjai Singh et al.The p53 tumor suppressor gene is the most commonly mutated gene in cancer. In breast cancer, the presence of p53 gene alterations has been associated with worse prognosis. This study was attempted to associate p53 gene mutations with its protein expression in North Eastern Indian population. We used single-stranded conformation polymorphism to screen samples for mutations in five conserved regions, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,244 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Alterations Induced by Amylin in Wistar RatsMohamed Mohamed Soliman, Zein Shaban IbrahimAmylin is a peptide hormone synthesized in β cells of pancreas together with insulin in response to glucose and nutrients. Amylin controls food intake and body weight but the exact mechanism is still unknown. This study aimed to examine the effects of amylin injection on hormones, metabolites and cytokines expression in rats. Wistar rats were injected amylin Intraperitoneally (IP) (10 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 7 Jun 2013 · 6,767 accessesView PDFCite
Research ArticleOpen accessIn the abstractA NAPIN PROMOTER ACTIVATES GENE EXPRESSION IN DEVELOPING SEEDS OF LESQUERELLA FENDLERIGrace Q. Chen, Jiann-Tsyh LinLesquerella fendleri produces industrial useful Hydroxy Fatty Acids (HFA) in seed oil. To improve oil and HFA of L. fendleri, it is desirable to use of seed-specific promoters to control the expression of target genes by genetic engineering. A seed-specific promoter fragment, -397 to -1 of a napin gene (PnapA) from Brassic napus was isolated by PCR and constructed to … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 18 Sep 2012 · 7,890 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Heirloom Tomato Polyphenol Extracts on Expression of Inflammation Genes in BovineKwaku Gyenai, Nona Mikiashvili, Hamid Ismail, Mulumebet WorkuThe effect of tomato on diseases of economic importance continues to be of broad interest. To evaluate these relationships, the effect of crude extracts of Cherokee purple tomato on pro-inflammatory genes and cytokines were evaluated. Neutrophils from three Holstein Fresian cows were treated with Phosphate Buffered Saline (PBS) or E. coli O111-B4 Lipopolysaccharide (LPS). Treated cells were exposed to different … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 3 · 25 Aug 2012 · 8,377 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Cyanobacterium Synechocystis sp. PCC 6803 Glutaredoxin Gene (slr1562) Protects Escherichia coli against Abiotic StressesAhmed Gaber, Salah El-Din El-AssalProblem statement: Glutaredoxins (GRXs) are ubiquitous small heat stable glutathione-dependent oxidoreductase enzymes that play a crucial role in plant development and response to oxidative stress. Approach: Cyanobacterium Synechocystis strain PCC 6803 contains two genes (slr1562 and ssr2061) encoding glutaredoxins. In the present investigation the slr1562 gene (grxC) was isolated and characterized. Results: The results revealed that the amino acid sequence … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 1 · 5 Mar 2012 · 7,582 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransformation of Lesquerella Fendleri with the New Binary Vector pGPro4-35SGrace Q. Chen, Roger Thilmony, Jiann-Tsyh LinProblem statement: Crop genetic engineering requires the use of various promoters to control the expression of introduced transgenes. Some of the binary vectors currently available for promoter characterization in dicotyledonous plants have pitfalls due to their construction, such as containing a selectable marker cassette with enhancer sequences that can potentially interfere with the expression specificity of nearby promoters. Also, many … …OnLine Journal of Biological Sciences, Vol. 11, Issue 3 · 19 Jan 2012 · 7,425 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficient Classification of Cancer using Support Vector Machines and Modified Extreme Learning Machine based on Analysis of Variance FeaturesA. Bharathi, A.M. NatarajanProblem statement: The primary objective is to propose efficient cancer classification techniques which provide reliable and significant classification accuracy. To achieve this primary research goal is to find the smallest set of genes that can ensure high accuracy in classification using supervised machine learning algorithms. The significance of finding the minimum subset is three fold: (a) The computational burden and … …American Journal of Applied Sciences, Vol. 8, Issue 12 · 22 Oct 2011 · 7,441 accessesView PDFCite
Research ArticleOpen accessIn the abstractInversion of Covariance Matrix for High Dimension DataSamruam ChongcharoenProblem statement: In the testing statistic problem for the mean vector of independent and identically distributed multivariate normal random vectors with unknown covariance matrix when the data has sample size less than the dimension n≤p, for example, the data came from DNA microarrays where a large number of gene expression levels are measured on relatively few subjects, the p×p sample … …Journal of Mathematics and Statistics, Vol. 7, Issue 3 · 27 Jul 2011 · 7,869 accessesView PDFCite
Research ArticleOpen accessIn the abstractCancer Classification using Support Vector Machines and Relevance Vector Machine based on Analysis of Variance FeaturesA. Bharathi, A.M. NatarajanProblem statement: The objective of this study is, to find the smallest set of genes that can ensure highly accurate classification of cancer from micro array data by using supervised machine learning algorithms. The significance of finding the minimum subset is three fold: The computational burden and noise arising from irrelevant genes are much reduced; the cost for cancer testing … …Journal of Computer Science, Vol. 7, Issue 9 · 25 Jul 2011 · 7,593 accessesView PDFCite