Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

28 results for “Flow Cytometry”
Set a search alert
Research ArticleOpen accessIn the abstractZeta Chain-Associated Protein-70 Expression is a Prognostic Tool in Mature and Precursor B-Cell NeoplasmNadia E. ElMenshawy, Sherin A. Abd ElAziz, Heba A. El Deghadi et al.Problem statement: The Zeta Chain-Associated Protein (ZAP) is a 70-kDa molecule associated with the zeta chain of the CD3 receptor complex of the lymphocyte population. It plays an important role in signaling initiation, activation T-cell receptor, phosphorylation of multiple downstream targets. So that believed as T. lymphocyte specific .Several studies is gathering that the pattern of expression is not lineage … …Current Research in Medicine, Vol. 2, Issue 1 · 9 Jul 2011 · 7,300 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Hematological and Alternate Markers in Human Immunodeficiency Virus Disease ProgressionK. V. Ramana, Jagadeeshwara Chary, V. Sabitha et al.Problem statement: The knowledge of HIV infection has expanded tremendously which has led to significant improvement in the treatment, leading to decrease in morbidity and mortality. Considering the limitations in using CD4+T-cell counts and HIV RNA viral load as markers in the HIV disease progression, physicians treating the HIV patients now look for alternate markers that predict HIV disease progression … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,375 accessesView PDFCite
Research ArticleOpen accessIn the abstractRal-Binding Protein is Required for the Maturation and Function of Dendritic CellsJozef Borvak, Mukesh Sahu, Varun Joy et al.Problem statement: Dendritic Cells (DCs) integrate responses of innate and adaptive immune system via transmitting pro-inflammatory and regulatory signals to naïve cells within draining lymph nodes. DCs have high capacity for endocytosis, both Clathrin-Dependent (CDE) and Caveolin-Dependent (CvDE). Approach: We have recently shown that ATP-hydrolysis by the multifunctional transporter protein RLIP76 is the primary determinant of the rate of CDE. … …American Journal of Immunology, Vol. 6, Issue 3 · 13 Sep 2010 · 8,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunodeficiency Provides Partial Protection from Bone Loss Induced by Castration and OvariectomyCedo M. Bagi, Edwin Berryman, Nels Hanson et al.Problem Statement: The interaction of osteoblasts and osteoclasts with cells of the immune system has been suggested as a contributing factor in the development of osteoporoses. Evidence from studies in rodents suggests that T cells play a significant role in bone loss following estrogen deficiency. The goal of this study was to investigate whether the lack of functional T cells … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,075 accessesView PDFCite
Research ArticleOpen accessIn the abstractApoptosis of human Breast Cancer Cells induced by Ethylacetate Extracts of PropolisSyamsudin, Partomuan Simanjuntak, Ratna Djamil, Wan Lelly HeffenProblem statement: Propolis has been ethno medically claimed to possess a wide array of biological activities including anticancer activity. The purpose of this research was to verify the folklore claim. Approach: This study was performed in a human breast carcinoma cell, MCF-7. Extract of propolis from different solvent, ethylacetate and n-buthanol showed induced apoptotic cells was detected by flow cytometry. … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 11,591 accessesView PDFCite
Research ArticleOpen accessIn the abstractCryptolepine Provokes Changes in the Expression of Cell Cycle Proteins in Growing CellsCharles Ansah, Nigel J. GooderhamProblem statement: Cryptolepine, the antimalarial plant alkaloid is cytotoxic to mammalian cells, but there is rather little understanding of the possible mechanisms involved in the cell-kill action of cryptolepine. Approach: We examined mammalian cells exposed to cryptolepine (0.5-5.0 μM) for effects on the cell cycle and associated alterations in the levels of major regulatory proteins using immunoblotting and flow cytometry. … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 7,400 accessesView PDFCite
Research ArticleOpen accessIn the abstractHyper-Ag-specific Ab Production in NC/Nga Mice is not associated with Deletion Polymorphism in the Promotor Region of the FcγRIIB GeneTohru Sakai, Mariko Nakamoto, Emi SutoProblem statement: NC/Nga (NC) mice produced high levels of ovalbumin (OVA)-specific IgG, IgG1 and IgG2a. We previously found deletion polymorphisms in the promoter region of fcgr2b in NC mice. To determine whether this mutation causes a hyper-humoral immune response, we generated congenic BALB/c mice carrying the NC-type fcgr2b allele (NC fcgr2b) and analyzed humoral immune response and FcγRIIB on germinal … …American Journal of Immunology, Vol. 5, Issue 3 · 31 Dec 2009 · 7,366 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Use of Artificial Neural Networks in Analysis Cationic Trypsinogen Gene and Hepatitis B Surface AntigenLiu Qicai, Zeng Kai, Zhuang Zehao et al.Problem statement: More and more severe hepatitis cases reported in China are infected with HBV and the immune response of HBV will be reduced if mutations occur in the TCR, therefore it is very important to investigate the relation of T-cellular function and clinical effect by studying the function of T-cell receptor. Approach: Artificial Neural Networks (ANN) was applied to … …American Journal of Immunology, Vol. 5, Issue 2 · 30 Apr 2009 · 7,566 accessesView PDFCite