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97 articles for “Dose Dependent”
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Research ArticleOpen accessIn the abstractAntioxidant, Analgesic and Anti-inflammatory Effects of Ethanolic Extract of Moroccan Lavandula stoechas L.Hind Ferehan, Mehdi Ait Laaradia, Sara Oufquir et al.Lavandula stoechas L. is a widely used medicinal plant. In Moroccan traditional medicine, it is employed for the treatment of different illness and as an anxiolytic, analgesic or anti-inflammatory remedy. The purpose of this investigation was to assess the antioxidant, antinociceptive and anti-inflammatory effects of the ethanolic extract of Moroccan Lavandula stoechas L. in animal models. Therefore, in vitro anti-oxidant … …OnLine Journal of Biological Sciences, Vol. 21, Issue 4 · 15 Feb 2022 · 5,891 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition Effect of Walnut Leaf Polysaccharide on HepG2 Cells in vitroShuqing Yang, Haifang Xiao, Shuyan Yu et al.In this study, the effect of Walnut Leaf Polysaccharides (WLP) on human liver tumor HepG2 cells was investigated. The results showed that WLP had dose-dependent and time-dependent inhibitory effects on HepG2 cell viability. Typical apoptosis characteristics were observed in WLP-treated HepG2 cells through 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl-benzimidazolyl-carbocyanine iodide (DAPI) staining and Acridine Orange (AO)/Ethidium Bromide (EB) dual staining. Meanwhile, significant decrease in Mitochondrial … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 29 Oct 2019 · 7,316 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization for the Extraction of Polysaccharide from Walnut (Juglans regia L.) Leaves: Antioxidant Activities in VitroShuqing Yang, Haifang Xiao, Shuyan Yu et al.Cellulase-assisted extraction of Walnut Leaf Polysaccharide (WLP) was studied. Single factor test and response surface design were employed to optimize the technological conditions. The consequences indicated that the highest WLP yield of 5.21% was achieved with raw material ratio of 50 mL/g, cellulase dose of 41488.52 U/g, enzymolysis pH of 5.88, enzymolysis time of 29.74 min and enzymolysis temperature of … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 23 Oct 2019 · 7,454 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtection of Human Albumin against UV-C Irradiation by Natural AntioxidantsAntonio Zuorro, Roberto LavecchiaThe use of UV-C light as a means to inactivate pathogens in biological media containing blood components or plasma derivatives has recently been rediscovered. Although highly effective, these treatments may have deleterious effects on plasma proteins such as albumin, fibrinogen and immunoglobulins. Here we investigate the use of three natural antioxidants, gallic acid, nicotinic acid and ascorbic acid, as potential … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 23 Oct 2018 · 9,925 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacological Properties of Bioactive Extracts from the Rhizome of Aristolochia longa LAmal El Hamsas El Youbi, Dalila BoustaAristolochia longa is a medicinal plant well known in Moroccan folk medicine for its activity against constipation, intestinal infections and skin diseases. The present study was performed to evaluate in vitro and in vivo immunomodulatory and cytotoxic activities of aqueous and protein extracts of A. longa. The in vitro immunomodulatory results showed that aqueous extract at 0.1 mg/mL enhanced T-lymphocyte … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 21 Jul 2020 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Ultra-High Pressure Technology on Isomerization and Antioxidant Activity of Lycopene in Solanum LycopersicumSiqun Jing, Zainixi Lasheng, Saisai Wang, Hui ShiTo evaluate the influence of the Ultra-High Pressure processing (UHP) on the isomerization and antioxidant activity of lycopene in tomatoes (Solanum lycopersicum), High Performance Liquid Chromatography (HPLC) and Ultraviolet-Visible Spectroscopy (UV-Vis) were used to separate and identify the isomer of lycopene. The scavenging activities against DPPH∙and∙OH present samples with and without UHP treatment were tested with ascorbic acid as positive … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 21 Jun 2020 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntioxidant Activity, Anti-Inflammatory and Analgesic Effects of Caralluma europaea (Eddaghmouss) in MiceAaziz Kebbou, Mehdi Ait Laaradia, Sara Oufquir et al.The aim of the current study is to evaluate the anti-inflammatory, antioxidant and analgesic properties of ethanolic (100 and 200 mg/kg, p.o.) and ethyl acetate extracts (100 and 200 mg/kg, p.o.) of Caralluma europaea. Formalin-induced paw licking test, Acetic Acid induced Writhing Test and Hot-PlateTest were used to assess the analgesic activity. Xylene-induced ear edema test was used to evaluate … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 24 Dec 2019 · 7,604 accessesView PDFCite
Review ArticleOpen accessIn the abstractImmune Metabolism in Functional Aspects of the BrainElisa Gonzalez Cuevas, Nitya G. ChakrabortyThe brain interacts with the immune system in a highly regulated and restricted manner. Immune signals initiate pro- and anti-inflammatory activity in most body tissues in response to disease states and injury. An accumulation of inflammatory insults can disrupt immune metabolic homeostasis and give rise to pathology in sensitive areas. Here, we provide an overview of interactions between immune metabolism … …American Journal of Immunology, Vol. 15, Issue 1 · 18 Dec 2019 · 7,222 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalgesic and Anti-inflammatory Activity of Euphorbia antiquorum LinnBanibrata Das, Samina Alam, Rajib Bhattacharjee, Biplab Kumar DasEuphorbia antiquorum (L.) is used as traditional medicine for various ailments in Bangladesh. But the scientific basis for its use especially in pain and inflammation remains largely unknown. Therefore, the present study was designed to evaluate analgesic and anti-inflammatory effect of the aqueous ethanolic extract of the whole plant. The analgesic activity was evaluated by hot plate, acetic acid induced … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 27 Aug 2015 · 9,213 accessesView PDFCite