106 results for “Chronic Disease (CD)”

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Literature ReviewOpen accessIn the abstractIntracranial Atherosclerotic Disease: Treatment Potential and Diagnostic OpportunitiesAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Anton Yuvenalievich Postnov et al.Atherosclerosis, characterized by the accumulation of atherosclerotic plaques within large arteries, substantially increases the risk of cardiovascular events, including ischemic stroke. Intracranial atherosclerotic disease (ICAD) represents a particularly significant clinical threat given its strong association with ischemic stroke across multiple intracranial arterial territories. This review provides a comprehensive analysis of the pathogenesis, diagnosis, and management of intracranial atherosclerosis. Special attention … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 5 May 2026 · 1,093 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOptimized Feature Selection for Kidney Ultrasound Image Classification Using Binary Coati Weighted Mean Vector AlgorithmFizhan Kausar, Ramamurthy B.The analysis of medical images presents many challenges, especially when making precise diagnoses. In pediatric Chronic Kidney Disease (CKD), early identification is critical because of its gradual progression to significant kidney failure. This study proposes a diagnostic framework for pediatric ultrasound image classification that incorporated machine learning and advanced feature selection methods. This approach is divided into four stages: Preprocessing, … …Journal of Computer Science, Vol. 21, Issue 12 · 22 Jan 2026 · 1,563 accessesView PDF Cite

Research ArticleOpen accessIn the abstractUsing Deep Learning to Support Clinical Decision-Making: The Case of Alzheimer’s Disease DiagnosisNawal Mohamed Bahy Eldin, Ghada A. El Khayat, Abeer A. AmerAlzheimer’s disease is a chronic, progressive brain disorder that leads to a gradual decline in memory and cognitive functions. In this study, N-VGG16, an advanced deep learning model, is proposed. The model builds upon the VGG16 architecture, incorporating key enhancements to improve its ability to classify neurodegenerative conditions. The model processes structural neuroimaging data using a refined pipeline that applies … …Journal of Computer Science, Vol. 21, Issue 10 · 11 Dec 2025 · 3,383 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComparative Analysis on Prediction of Chronic KidneyDisease by various Machine Learning ModelsNikhil Verma, Tripti Sharma, Bobbinpreet Kaur, Ayush DograChronic Kidney Disease (CKD) is a prevalent global healthconcern, which is affecting a number of people in the whole world. Earlydetection & precise checking of CKD are really important for essentialsupervision & intervention to prevent disease progression and associatedcomplications. Machine learning (ML) models have emerged as favourabletools for CKD detection due to their ability to analyse complex data patternsand provide … …Journal of Computer Science, Vol. 21, Issue 6 · 24 May 2025 · 5,939 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnchoring Public Health Forecasts: High-Precision Obesity Prevalence Estimation Via Hybrid Geodemographic Ensemble RegressionTrenton Ward, Isaac OsunmakindeObesity remains a major driver of chronic disease and rising healthcare costs in the United States. Yet, most existing predictive models rely on single-model classifiers and rarely incorporate spatial structure or ensemble-based regression, thereby limiting their ability to capture geodemographic variation. This study introduces a hybrid unsupervised–supervised ensemble framework that integrates K-Means spatial profiling with a Stacking Regressor to address … …Journal of Computer Science, Vol. 22, Issue 7 · 31 Jul 2026 · 632 accessesView PDF Cite

Research ArticleOpen accessIn the abstractsuPAR as an Inflammatory and Preclinical Atherosclerotic Marker in Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Neelam Manjunath Pawar et al.The mechanistic link between inflammation and atherosclerosis highlights the critical role of immune modulation in cardiovascular disease. The soluble urokinase plasminogen activator receptor (suPAR), an immune-derived factor, has recently emerged as a non-specific inflammatory marker across chronic diseases and infections. All cells within the atherosclerotic arterial wall can express uPAR and release urokinase, which plays a key role in the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 30 Mar 2026 · 1,122 accessesView PDF Cite

Review ArticleOpen accessIn the abstractOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,675 accessesView PDF Cite

Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDF Cite

Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDF Cite

Case ReportOpen accessIn the abstractHistopathology of Microbially Induced Corrosion and Cluster Failure of Moderately Rough Surface Oral Implants in a Resident Bone MicrobiotaStephen Nelson, Helen Hu et al.This case report presents as a maxillary "cluster-failure", where six moderately rough-surface oral implants (1-2 microns) were installed to support a full-arch hybrid bridge. Understanding cluster failures requires the acknowledgment of biofilm science that recognizes the persistence of bacterial infection in bone following extraction and the need to bioremediate the bone-bed, by surgical debridement, before implant installation. The patient, a … …Current Research in Dentistry, Vol. 15, Issue 1 · 28 Feb 2024 · 8,482 accessesView PDF Cite