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43 results for “Cell viability”
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Research ArticleOpen accessIn the abstractSynthesis, Ant Proliferative Activity and Docking Study of New Quercetin Derivatives against MDA-MB231 Breast Cancer Cell LinesReham Adnan Al-Anssari, Rita S. Elias, Shaker A.N. AljadaanMDA-MB231 is a very aggressive and invasive triple negative breast cancer, which present with limited treatment options. Unlike other breast cancer types, it is characterized by absence of hormonal receptors of estrogen, progesterone as well as human epidermal growth factor receptor 2, rendering it unsuitable for hormonal therapy and a perfect candidate for chemotherapy. Quercetin is a common natural flavonoid … …American Journal of Applied Sciences, Vol. 16, Issue 5 · 26 Jun 2019 · 8,790 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vascular Endothelial Growth Factor (VEGF) on Dental Pulp Stem Cells (DPSC)Eric Mullins, Cale Forgues, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. Studies of DPSC differentiation have demonstrated the potential to form many tissue types, including neural, osteogenic and vascular precursors using cytokines and growth factors, such as Vascular Endothelial Growth Factor (VEGF). Eight previously isolated Dental Pulp Stem Cell (DPSC) … …Current Research in Medicine, Vol. 9, Issue 1 · 1 Jun 2019 · 13,831 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytotoxic Activity of Tinospora crispa Crude Extracts (Stem) Against K562 Human Leukemia CellsNormah Awang, Haziratul Iffah Ruzali, Rapidah Mohamad et al.Tinospora crispa (T. crispa) is traditionally used as an herbal medicine for treatment of gout and is an analgesic, anti-inflammatory and antihyperuricemic agent. Cytotoxicity of hexane, dichloromethane, ethanol and aqueous extracts of T. crispa stem against K562 cells was assessed. Crude extracts of T. crispa stem were obtained by sonication and maceration methods. T. crispa stem powder was macerated and … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 11 May 2019 · 7,870 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Action of Bovine Cartilage on Tumor Cells In Vitro And In VivoArax Tanelian, Alexander M. AbdelnoorIn an earlier study we had investigated the effect of Bovine Cartilage (BC) on mouse melanoma cells. In pursuant to this study BC anti-tumor activity in vitro against several human tumor cell lines was evaluated, mechanism by which BC induces tumor cell death was studied and its immunogenicity was assessed. Five mice received Intraperitoneal (IP) injection of BC once every … …American Journal of Immunology, Vol. 14, Issue 1 · 23 Jan 2018 · 9,664 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiocompatibility of Orthodontic Resins: In vitro Evaluation of Monomer Leaching and Cytotoxic EffectsRoberto Uomo, Gianrico Spagnuolo, Giuseppina Nocca et al.The aim of this study was to investigate the effect of orthodontic resins on cell survival and to evaluate monomer leaching both before and after resin polymerization. Materials and methods: 3T3 mouse fibroblasts were exposed to three cured and uncured orthodontic resins. Cellular viability was assessed by Alamar Blue assay after 24, 48 and 72 h. High Performance Liquid Chromatography … …Current Research in Dentistry, Vol. 8, Issue 1 · 7 Jul 2017 · 16,333 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment of an Immunomagnetic Separation Method for Viable Salmonella Typhimurium Detected by Flow CytometryShakil Ahmed, Horst-Günter Rubahn, Helmut ErdmannA very small number of bacterial pathogens may have fatal effects on food safety. In spite of having great advancements in bioanalytical methods, most of the accepted detection methods are still cultivation based and thus time consuming. This leads to an intense need for efficient and rapid methods for detection of food-related bacteria. In this study, a flow cytometry based … …OnLine Journal of Biological Sciences, Vol. 16, Issue 4 · 25 Nov 2016 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the abstractPassage Effect on Aging of Human Umbilical Cord Derived Mesenchymal Stem CellDian Mediana, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Noviyanti GoeiTo be used in regenerative medicine, cells should be checked for various conditions, including cell aging. This study aimed to learn senescent profile and its relation to cell viability, proliferation and cell size in various passages, which were done in α-MEM-10% PRP medium, until senescence-associated β-galactosidase (SA-β-Gal) positive cells were found. Stem cells were isolated from umbilical cord tissue by … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 31 Jul 2015 · 8,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrenatal Ethanol Exposure Affects the Proliferation and Differentiation of the Osteoblasts from Newborn RatsIsabel Chaves Silva Carvalho, Dennia Perez de Andrade, Noala Vicensoto Moreira Milhan et al.Alcohol exerts teratogenic effects and its consumption during pregnancy may cause various alterations in the fetus, including deficit of bone development. The objective of this study was to evaluate the initial responses, on osteoblasts isolated from newborn rat calvaria, after prenatal ethanol exposure. Nine pregnant rats were divided into three groups according to the diet fed during pregnancy: Rats fed … …OnLine Journal of Biological Sciences, Vol. 15, Issue 3 · 14 Jul 2015 · 6,704 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Platelet Rich Plasma on Post Cryopreservation Viability, Morphology and Proliferation of Human Umbilical Cord Stem CellsNoviyanti Goei, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Dian MedianaIn most cryopreservation medium, Fetal Bovine Serum (FBS) is used as supplement, while it is well known that FBS contains xenoproteins that can be incorporated into the cells and may be harmfull, as they can elicit immune response. Therefore, finding other xenofree materials as FBS alternative in cryopreservation medium is very important. Platelet Rich Plasma (PRP) is albumin rich and … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 4 Jun 2015 · 7,386 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Gc-Macrophage Activating Factor in Human Neurons; Implications for Treatment of Chronic Fatigue SyndromeRodney Smith, Lynda Thyer, Emma Ward et al.Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease of multifactorial aetiology characterized by immune system dysfunction, widespread inflammation, multisystemic neuropathology and persistent pain. Given the central role of the immune system in the pathogenesis of the syndrome, we studied the effects of a potent modulator of the immune system in in vitro and in vivo models that could help … …American Journal of Immunology, Vol. 9, Issue 4 · 6 Nov 2013 · 10,982 accessesView PDFCite