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61 results for “Cell Lines”

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Research ArticleOpen accessIn the abstractModeling and Simulation of the Impact of Temperature on Single Point Load Cell using Trnsys 16.0: Measured, Uncompensated and Error Data for Zaria Kaduna StateAlbright A. Edet, Afolayan M. O., Umar A. UmarA load cell is a piece of machined metal called a transducer or load sensor. As a measuring device, the entire framework is prone to the impact of environmental forces which can produce errors in the load cell output. The most significant force or input modifier is high ambient temperature. Typical meteorological year document demonstrates that in March, April, and … …Journal of Mechatronics and Robotics, Vol. 6, Issue 1 · 7 Jun 2022 · 5,727 accessesView PDFCite
Research ArticleOpen accessIn the abstractSelective Susceptibility of Human Bladder Transitional Cell Carcinoma T24 Cells towards NBD PeptideSankari Durairajan, Charles Emmanuel Jebaraj Walter, Kalaiselvi Periyandavan et al.Bladder cancer is a recurrent disease that often develops chemoresistance and is on the rise in developing countries. After diagnosis surgery followed by immunotherapy and/or chemo- radiation therapy are the available treatments. These treatments do not provide protection against disease progression or recurrence thus highlighting the need to identify and develop drugs that are capable of inhibiting bladder cancer. T24 … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 20 Apr 2020 · 7,787 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical Significance of Precise Hyperthermic Intraperitoneal Chemotherapy Up-regulation RP11-356I2.2 Restraining the Occurrence and Development of Gastric CancerYu Yan, Feng Yanlin, Feng Jinxin et al.In order to study the therapeutic effect and possible mechanism of Precise Hyperthermic Intraperitoneal Chemotherapy (HIPEC) on gastric cancer, the expression of RP11-356I2.2 in gastric cancer cell lines and tissues was detected by real-time fluorescence quantitative PCR (RT-PCR). Chi-square test was used to analyze the correlation between the expression and clinic pathological parameters. Western blotting was used to detect the … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 4 Jun 2020 · 6,487 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vitro Immunomodulatory and Cytotoxic Potentials of Faloak (Sterculia quadrifida R.Br.) BarkTriana Hertiani, Purwantiningsih, Aji Winanta et al.Faloak (Sterculia quadrifida R.Br., Sterculiaceae) is an Indonesia indigenous plant widely used as a traditional remedy for various health complaints. This study aimed to explore the immunomodulatory and cytotoxicity potentials of Faloak bark by using in vitro techniques. Barks was extracted using water, ethanol and ethanol: water (1:1) separately. Colorimetric analysis was used for the determination of the total phenolic … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 6 Nov 2019 · 8,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractSequence Analysis of Scaffold/Matrix Attachment Regions (S/MARs) From Human Embryonic Kidney and Chinese Hamster Ovary CellsNur Shazwani Mohd Pilus, Azrin Ahmad, Nurul Yuziana Mohd YusofBinding of intergenic Scaffold/Matrix Attachment Regions (S/MARs) to nuclear matrix proteins is believed to poise adjacent genes for transcription by forming chromatin loops. Vector constructs containing Scaffold/Matrix Attachment Regions (S/MAR) flanking the gene of interest, therefore, are able to enhance recombinant protein expression in mammalian cells. We compared two methods that are based on buffers containing 2M NaCl and Lithium-3,5-diidosalicylate … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 8 Oct 2018 · 7,630 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Action of Bovine Cartilage on Tumor Cells In Vitro And In VivoArax Tanelian, Alexander M. AbdelnoorIn an earlier study we had investigated the effect of Bovine Cartilage (BC) on mouse melanoma cells. In pursuant to this study BC anti-tumor activity in vitro against several human tumor cell lines was evaluated, mechanism by which BC induces tumor cell death was studied and its immunogenicity was assessed. Five mice received Intraperitoneal (IP) injection of BC once every … …American Journal of Immunology, Vol. 14, Issue 1 · 23 Jan 2018 · 9,664 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Compounds from Sponge Associated Bacteria: Anticancer Activity and NRPS-PKS Gene Expression in Different Carbon SourcesJepri Agung Priyanto, Rika Indri Astuti, Jun Nomura, Aris Tri WahyudiSponge associated bacteria with diverse NRPS-PKS genes could be the alternative source of bioactive compounds. This study aimed to analyze the activity as well as the regulatory mechanism regarding the anticancer properties derived from these bacteria against cancer cell lines. Extraction of bacterial metabolites using ethyl acetate solvent resulted yield ranging from 0.003 to 0.016% (w/v). Six extracts of bacterial … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 5 Oct 2017 · 8,886 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Triple Immune Argument; Surveillance/Evasion/ Senescence and the Increased Incidence of Acute Myeloid Leukemia Observed with AgeManar M. IsmailAML originates from genetic insults of hematopoietic stem and progenitor cells (HSPCs/HSCs) that was identified earlier as leukemia stem cells (LSCs). In quiescent state, trafficking immune cells are crucial for eradication of aberrant clones and obtaining balance between proliferation and apoptosis to maintain HSCs pool. Regulatory T-cells shield the HSCs from the inflammatory reactions by suppressing T- and B- cells. … …American Journal of Immunology, Vol. 13, Issue 4 · 22 Dec 2017 · 7,806 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudying Interrelation of PDLIM4 with the Model of CD74-Mediated Development of Breast CancerDmitry Sergeevich Kravchenko, Yuriy Nikolaevich Lezhnin, Anna Evgenyevna Ivanova et al.Mammary gland tumors are often characterized by deregulation of RIL/PDLIM4 expression, however, PDLIM4-mediated mechanisms of cancer development still remain unknown. The aim of our research was to study the influence of PDLIM4-deregulation on transcript me changes of malignized cells. We performed а comparative NGS-analysis of breast cancer cell lines with suppressed and induced expression of PDLIM4 and identified a number … …OnLine Journal of Biological Sciences, Vol. 17, Issue 2 · 3 Jun 2017 · 7,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Public Health Significance of Non-Polio Enteroviruses in Healthy Nigerian ChildrenMuhammad Sagir Shehu, Yunusa Thairu, Idris Abdullahi Nasir, Fatima YahayaNon-Polio Enteroviruses (NPEVs) are in circulation all over the world. Some of these viruses have been associated with several chronic diseases such as cardiopathy, myositis, acute flaccid and spastic paralysis in children which mimic poliomyelitis. This study sought to ascertain whether Non-Polio Enteroviruses (NPEVs) are silently shed by apparently healthy school children in Bauchi state, Nigeria. This cross-sectional study involved … …American Journal of Infectious Diseases, Vol. 12, Issue 1 · 24 Mar 2016 · 7,691 accessesView PDFCite