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66 articles for “Cardiovascular risk”
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Research ArticleOpen accessIn the abstractRandom Forest-Based Genome Analysis for Disease Association and SNP Marker IdentificationXiangdong LiuAt present, genomic data analysis has the problems of insufficient model interpretation and limited computational efficiency in disease association research. As a powerful machine learning algorithm, Random Forest has demonstrated excellent ability in processing complex and multi-dimensional data sets and has gradually become a popular tool in the field of bioinformatics. The purpose of this paper is to explore how … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Jul 2025 · 5,533 accessesView PDFCite
Literature ReviewOpen accessIn the abstractAtherosclerosis and Alzheimer’s Disease Interconnection: Inflammation, Aβ and MoreAnastasia Vladimirovna Poznyak, Victoria Khotina, Roghayyeh Vakili-Ghartavol et al.Despite being the leading cause of CVD and cardiovascular mortality globally, Atherosclerosis (ATH) remains underdiagnosed and undertreated. The reasons behind Alzheimer’s Disease (AD) also remain unclear and there is currently no cure for it. At present, at least 55 million people are believed to be suffering from the disorder and the figures are expected to grow. At the same time, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 26 May 2024 · 4,761 accessesView PDFCite
Literature ReviewOpen accessIn the abstractAtherosclerosis as Age-Related Disease: The Potential of Sirtuins TreatmentAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis, a global health concern, has attracted researchers worldwide due to its severe consequences. The elderly are particularly susceptible to cardiovascular diseases and events, making them a high-risk group. Although gaps in our understanding of atherosclerosis pathogenesis persist, it is evident that oxidative stress, endothelial dysfunction, inflammation, mitochondrial dysfunction, and autophagy impairments are key components of its development. Remarkably, these … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 May 2024 · 4,717 accessesView PDFCite
Review ArticleOpen accessIn the abstractFemale Sex Hormones Contribute to Vulnerability to Athero-Sclerosis: Overview of Mechanisms and Specific Risk FactorsAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis poses a significant challenge to the general population, with its prevalence particularly prominent among older individuals. Age, however, is not the sole determinant of risk, as gender also plays a crucial role. Sex-related disparities exist not only in the incidence of atherosclerosis but also in its progression and development. The intricate interplay of hormones in the female reproductive system … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 11 Jan 2024 · 4,633 accessesView PDFCite
Research ArticleOpen accessIn the abstractSurvey and Distribution of Plant Parasitic Nematodes on Tomato at Baruasagar in Jhansi (India)Abha Sachan, Rajesh Kumar Pandey, Shailendra Kumar et al.Tomato (Lycopersicon esculentum) is an important high-value vegetable crop and acts as a natural medicine that alleviates the risk of a condition such as cancer and cardiovascular disease. Plant parasitic nematodes are obligate biotrophic feeders that cause the most devastating phytoeconomic damage to tomato cultivation across the globe. Their infection may lead to a spectrum of disorders like stunting, necrosis … …American Journal of Agricultural and Biological Sciences, Vol. 18, Issue 1 · 10 Jan 2024 · 6,816 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Benefits of Selected Nutritional Compounds Towards Atherosclerosis ManagementAnastasia Vladimirovna Poznyak, Mariam Bagheri Ekta, Vasily Nikolaevich Sukhorukov et al.Globally, the prevalence of obesity, type 2 diabetes, and metabolic syndrome is steadily rising, potentially giving rise to the most extensive non-communicable health crisis ever recorded blocking the flow are able to break and cause a blood clot. The possible consequence is a significant increase in atherosclerotic cardiovascular disease rate. The atherosclerotic cardiovascular disease largely depends on modifiable factors, however, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 2 Nov 2023 · 5,032 accessesView PDFCite
Review ArticleOpen accessIn the abstractBrief Overview of Specific Features of Cancer in Atherosclerosis Patients and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Cardiovascular Conditions (CVD) as well as cancer are the main death causes globally. Characteristically, there are numerous interrelations and intersections between these two groups of diseases. So, in particular, cardiovascular disease is one of the main comorbidities and death causes in cancer patients. The development of atherosclerosis is promoted by aggressive anticancer therapy regimens and various risk factors, including hypertension, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 22 Sep 2023 · 4,521 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine ConcentrationJae-Sik Jeon, Eun Ju Oh, Qian-Wen Wang, Jae Kyung KimParticulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological diseases, and pregnancy complications, and contributes to both mortality and morbidity globally. PM can also influence the autonomic nervous system. The evidence suggests that the likelihood of developing lung cancer continually … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 20 Feb 2023 · 5,450 accessesView PDFCite
Review ArticleOpen accessIn the abstractCoenzyme Q10 Supplementation Effect on Systemic DiseasesAya Jabbar HusseinThis review paper aims to examine recent RandomizedClinical Trials (RCTs) and review articles evaluating the role of CoQ10 in themanagement of atherosclerosis, and coronary heart disease, with particularfocus on Statin-Associated Muscle Symptoms (SAMS), chronic heart failure, andthe effect on cardiovascular risk factors. With an evaluation of its impacts onpatients' well‐being, it seeks to outline the existing opportunities for usingCoQ10 in … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 20 Oct 2022 · 6,525 accessesView PDFCite
Review ArticleOpen accessIn the abstractSARS-CoV-2-Induced Damage on the Cardiovascular System: Molecular MechanismsMel·lina Pinsach-Abuin, Ramon Brugada TerradellasSince its emergence in late December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the causative agent of coronavirus disease 2019 (COVID-19) - has spread rapidly world-wide, becoming a global pandemic in March 2020 that is still active. In addition to the severe pulmonary damage, clinical studies have reported that COVID-19 is associated with the development of cardiovascular … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 25 Nov 2021 · 6,791 accessesView PDFCite