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52 articles for “Cancers”
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Research ArticleOpen accessIn the abstractSPECTRAL DOMAIN FEATURES FOR OVARIAN CANCER DATA ANALYSISAhmed Farag Seddik, Riham Amin Hassan, Mahmoud A. FakhreldeinThe early detection of cancer is crucial for successful treatment. Medical researchers have investigated a number of early-diagnosis techniques. Recently, they have discovered that some cancers affect the concentration of certain molecules in the blood, which allows early diagnosis by analyzing the blood mass spectrum. Researchers have developed several techniques for the analysis of the mass-spectrum curve analysis and used … …Journal of Computer Science, Vol. 9, Issue 8 · 9 Jul 2013 · 6,915 accessesView PDFCite
Research ArticleOpen accessIn the abstracttNOX (ENOX2) Target for Chemosensitization-Low-Dose Responses in the Hormetic Concentration RangeD. James Morre, Sara Dick, Elena Bosneaga et al.An emerging concept of cancer chemotherapy is that of chemosensitization. Most often applied to the treatment of drug-resistance cancers, chemosensitization has utility when such cancers are rendered drug sensitive through treatment with the sensitizing agent. A particularly striking example of chemosensitization is that encountered with the synthetic isoflavene phenoxodiol where patients with taxane- and/or platinum-resistant ovarian carcinoma once again become … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,568 accessesView PDFCite
Research ArticleOpen accessIn the abstractAqueous Extract of Inonotus bliquus (Fr.) Pilat (Hymenochaetaceae) Significantly Inhibits the Growth of Sarcoma 180 by Inducing ApoptosisCaifa Chen, Weifa Zheng, Xiaowen Gao et al.Inonotus obliquus (Fr.) Pilat (Hymenochaetaceae) has been widely used as a folk medicine to treat various cancers in Russia, Poland and most of Baltic countries for literally more than four centuries. However, in spite of its therapeutic significance for cancers, this fungus has not been studied systematically for the mechanisms of antitumor activity. In this study, we report the effects … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 1 · 31 Mar 2007 · 21,110 accessesView PDFCite
Research ArticleOpen accessIn the abstractSensitivities of Uterine Adenocarcinoma, Mixed Mullerian Tumor (MMT) and Sarcoma Cell Lines to Chemotherapeutic Agents and a Flex-Het DrugJohnny Hyde, Doris M. BenbrookThe administration and combination of a variety of chemotherapeutic agents for treatment of advanced or recurrent uterine cancer of different histologies is under current debate. Mixed Mullerian Tumors (MMTs), which contain both adenocarcinoma and sarcoma components, are the most rate histologic type and it is therefore difficult to conduct clinical trials to determine if they should be treated like endometrial … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Phenotypically Suppressed Cancer Cell As a Therapeutic TargetKimberly D. Kyker, Jessica E. Thorpe, Satyendra S. Shenoy et al.Bladder cancer recurs in up to 70% of patients judged to be tumor-free after treatment. Like other cancers, delayed appearance of metastases is common. These findings suggest the malignant phenotype can be suppressed, to emerge later. Following up on previous research in our laboratory showing that normal extracellular matrix can suppress the malignant phenotype of bladder cancers, we here demonstrate … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,471 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence and Histopathologic Analyses of Mammary Tumors in Female Dogs in the Northeast of AlgeriaZahra GABLI, Leila BEDDAR, Amir Agabou et al.Cancers development and complications are a major cause of death in dogs all over the world. The current study attempts to describe the prevalence and anatomo-pathologic traits of mammary gland tumors (MGTs) in bitches in northeast Algeria. From November 2013 to April 2016, a total of 215 bitches originating from four provinces (Constantine, Oum El Bouaghi, Annaba and Skikda) were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 26 Sep 2017 · 7,546 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Bioactivity of Fucoxanthin from Undaria pinnatifida in VitroYiting Li, Ye Liu, Yuepeng Wang et al.Fucoxanthin, a marine carotenoid, can be found in marine algae and some marine invertebrates, has remarkable biological properties for human health. It is known that fucoxanthin has anti-cancer activity on some human cancer cells such as human colon cancers, leukemia cells, prostate cancer cells, breast cancer cells. In this study, the fucoxanthin was extracted from Undaria pinnatifida, after purification by … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 7 Jun 2016 · 7,866 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Practical Consideration of Poliovirus as an Oncolytic VirotherapyElizabeth Denniston, Hannah Crewdson, Nicole Rucinsky et al.The inauguration of novel treatment strategies into the clinical setting faces a number of hurdles. In addition to treatment efficacy and safety, acceptance by doctors and patients is paramount to the success of novel therapies. Although viruses are the cause of numerous infectious diseases, these acellular entities have been harnessed over the years to benefit mankind. Recently, a recombinant Poliovirus-Rhinovirus … …Current Research in Virology, Vol. 5, Issue 1 · 3 Mar 2016 · 27,150 accessesView PDFCite
Review ArticleOpen accessIn the abstractHypermethylation and Hypomethylation of DNA: Implication for Diagnosis and Prognosis of Prostate CancerLubos Danisovic, Stanislav ZiaranProstate cancer belongs to the most common cancers and it is the second leading cause of cancer death in men. A genetic predisposition with epigenetic changes in DNA contributes to the development of the disease. DNA hypermethylation and hypomethylation belong to the most studied epigenetic changes in prostate cancer development. Both forms may lead to chromosomal instability and transcriptional gene … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 13 Jun 2015 · 6,528 accessesView PDFCite