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410 results for “Cancer”
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Research ArticleOpen accessEvery word in the titleMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,144 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,398 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAssociation Between Cancer Screening Results Using Single Nucleotide Polymorphism and Cancer Incidence Rate in Korean WomenKyung Bae Lee, Jae Kyung KimIn this study, we investigated the usefulness of Single Nucleotide Polymorphism (SNP) testing in assessing cancer susceptibility in women by evaluating correlations between SNP testing results and cancer incidence rates. SNP testing was conducted on blood samples of women who underwent health examinations commissioned by medical institutions in the Republic of Korea in 2017 using real-time polymerase chain reaction with … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 25 Sep 2023 · 4,956 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleBrief Overview of Specific Features of Cancer in Atherosclerosis Patients and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Cardiovascular Conditions (CVD) as well as cancer are the main death causes globally. Characteristically, there are numerous interrelations and intersections between these two groups of diseases. So, in particular, cardiovascular disease is one of the main comorbidities and death causes in cancer patients. The development of atherosclerosis is promoted by aggressive anticancer therapy regimens and various risk factors, including hypertension, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 22 Sep 2023 · 4,521 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRadial Basis Function Networks and Contrast-Limited Adaptive Histogram Equalization Filter Based Early-Stage Breast Cancer Detection TechniquesAnitha Ponraj, Aroul CanessaneBreast cancer is one of the most common types of cancer that kills women. When cells become uncontrollably large, cancer develops. As a result, detecting and classifying breast cancer in its early stages is essential so that patients can take the appropriate precautions. On the other hand, mammography images have relatively low sensitivity and effectiveness in detecting breast cancer. Furthermore, … …Journal of Computer Science, Vol. 19, Issue 6 · 25 May 2023 · 5,613 accessesView PDFCite
Short CommunicationsOpen accessEvery word in the titleCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Comprehensive Review on Skin Cancer Detection Strategies using Deep Neural NetworksAkepati Sankar Reddy, Gopinath M. PSkincancer is a deadly malignancy. Incomplete D.N.A. repair in skin cells causeshereditary mutations and cancer. Early skin cancer is easier to treat since itspreads slowly to other body areas. As a result, the optimal time to find it isduring its infancy. Because of the rising frequency of skin cancer, the highmortality rate, and the high cost of medical treatment, early … …Journal of Computer Science, Vol. 18, Issue 10 · 5 Oct 2022 · 6,400 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClassification of Non-Small Cell Lung Cancer Based on Gene Expression in Cases of Smokers and Non-Smokers using Ensemble Methods with Statistical Based Feature SelectionFhira Nhita, Isman KurniawanLung cancer is one of the leading causes of death globally. One of the main risk factors for lung can ceris smoking, which causes more than 90% of lung cancer cases. There are two types of lung cancer, i.e., Small Cell Lung Cancer (SCLC) and Non-Small Cell Lung Cancer (NSCLC), which the latter is the most common. One method that … …Journal of Computer Science, Vol. 18, Issue 10 · 30 Sep 2022 · 6,093 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDifferential Expression of Cellular and Exosomal MicroRNA Isolated from Oral Cancer Cells and their Resistance to ChemotherapyBrady Petersen, Carl Yu, Samuel Hutchings et al.MicroRNAs are abundant small non-coding RNA with a variety of known functions, including transcriptional activation and inhibition. Recent evidence has suggested that microRNA expression may influence the responsiveness of some cancers to chemotherapy, including liver and lung cancers. Some evidence has now suggested that specific microRNAs, such as miR-21, miR-155, and miR-375, may influence oral cancer responsiveness to chemotherapy – … …Current Research in Dentistry, Vol. 13, Issue 1 · 29 Jul 2022 · 5,902 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClassify Breast Cancer Patients using Hybrid Data-Mining TechniquesFaris E. Mohammed, Nadia Smaoui Zghal, Dalinda Ben Aissa, Mostafa Mahmoud El-GayarAccording to the World Health Organization (WHO), breast cancer is a disease that leads to death, especially for women who have neglected or ignored the risk factors. Doctors can classify patients according to clinical information, famous disease symptoms, or similar cases. But, some cases are difficult to detect early or diagnose accurately. Therefore, the most important challenge faced by researchers … …Journal of Computer Science, Vol. 18, Issue 4 · 12 May 2022 · 6,526 accessesView PDFCite