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89 articles for “Anti-Inflammatory”
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Research ArticleOpen accessIn the keywordsEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,679 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Effect of a Prophylactic Dose of Ibuprofen on Plasma Level of Interleukin 1, Interleukin 6 and Tumor Necrosis Factor-Alpha in a 1500 m Running PracticeGholamreza Sepehri, Mohammad Pourranjbar, Ghollam-Reza Moshtaghi-Kashanian et al.Problem statement: there are controversies about the effects of anti-inflammatory drugs on exercised induced changes on plasma cytokines in untrained male athletes, so the primary purpose of this study was to measure the influence of a prophylactic dose of ibuprofen use on plasma cytokines during a 1500 m running race. Approach: Subjects were 10 untrained male Medical University students who … …American Journal of Applied Sciences, Vol. 8, Issue 1 · 31 Jan 2011 · 7,886 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPossible Mechanism of Plumbago zeylanica in Prevention of Hepatic Dammage in Wistar RatRohit Goyal, Pyare Lal SharmaPlumbago zeylanica root has been used traditionally to treat various body ailments including liver diseases. The present study was designed to investigate the hepatoprotective effects of standardized methanolic extract of Plumbago zeylanica root on paracetamol, CCl4 and alcohol induced hepatic injuries in rats and its possible mechanism(s) of hepatoprotection. Administration of hepatotoxicants like paracetamol (3 g kg-1, p.o.) or CCl4 … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,638 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTramadol Vs Tapentadol: Anew Horizon in Pain Treatment?Mario GiorgiProblem statement: Acute and chronic pain is a common presenting sign in animal species and human beings. Approach: Classical opioids provide very effective pain relief, although they may be less effective in the treatment of chronic pain due to their limited therapeutic windows and the induced opioid receptor down regulation. Atypical opioids, such as tramadol and tapentadol, have a dual … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 25 Feb 2012 · 17,871 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction of an Achillea millefolium (Yarrow) Toothpaste to Combat Gum and Tooth PainMunashe K. F. Chakamanga, Ashley Kumalo K, Dirk Hamadziripi MGum inflammation also known as gingivitis is primarily caused by the accumulation of dental plaque that forms on teeth. The inflammation triggers pain in the gums and surrounding tissues due to increased blood flow and immune activity aimed at combating the bacterial infection. Thus, this study was carried out to investigate the efficacy of Yarrow-based toothpaste in reducing gum inflammation. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 9 Oct 2026 · 420 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Metformin Treatment on Inflammatory Factors and Gut Microbial Diversity in Patients with Type II Diabetes MellitusLei Tong, Jingjing Zhang, Li Xiao Yue et al.With the persistent rise in the prevalence of Type 2 Diabetes Mellitus (T2DM), traditional treatment evaluations have primarily focused on glycemic control, often overlooking the multidimensional effects of medications. As a first-line therapeutic agent, the anti-inflammatory effects and gut microbiota regulation mechanisms of metformin remain incompletely elucidated. This prospective cohort study established a metformin treatment group and a T2DM control … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 20 Jul 2026 · 774 accessesView PDFCite
Research ArticleOpen accessIn the abstractInverse Correlation Between α-Klotho and Diabetic Biomarkers in Type 2 Diabetes: A Cross-Sectional StudyYaser A.M Sulaiman, Moayad M. Al Anzy, Omeed Akbar Ali, Adnan M. IsmailEvidence suggests a link between diabetes and Klotho protein, demonstrated by reduced Klotho gene expression in individuals with diabetes, α- klotho the potential modulator of kidney health in DM. Klotho is primarily expressed in the kidneys and has an anti-inflammatory and antioxidant role, which may protect against the pathological processes that damage renal function in diabetes. Research conducted in Japan … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 2 Jul 2026 · 837 accessesView PDFCite
Research ArticleOpen accessIn the abstractAluminium-Induced Hepatotoxicity and the Protective Role of Withania somnifera (Ashwagandha) in Wistar RatsAnchana Babu, Rekha D Kini, Nayanatara Arun Kumar, Megha GokulAluminium is a widely distributed environmental contaminant whose chronic exposure leads to accumulation in multiple organs, including the liver, resulting in oxidative stress and tissue damage. When reactive oxygen species production exceeds the body's antioxidant defense capacity, cellular injury ensues — a mechanism central to aluminium-induced hepatotoxicity. Withania somnifera (Ashwagandha), an evergreen herb of the Solanaceae family widely cultivated in … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 6 Apr 2026 · 1,449 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Murraya paniculata Leaf Flour in Reducing Subclinical Mastitis in Dairy Goats Fed Date Pulp-Based DietsDwierra Evvyernie, Endah Yuniarti, Rika Zahera, Anuraga JayanegaraSubclinical mastitis is a major concern in dairy production, leading to economic losses and antibiotic dependence, which poses risks of milk residue contamination. As a natural alternative, orange jasmine (Murraya paniculata) leaves, rich in flavonoids, exhibit antimicrobial and anti-inflammatory properties. This study investigated the effects of incorporating date pulp and orange jasmine leaf flour (OLF) into the diets of lactating … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 21 Feb 2026 · 1,590 accessesView PDFCite