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Research ArticleOpen accessIn the abstractGilsonite Modified Asphalt for Use in Pavement ConstructionAliasghar Akbari Nasrekani, Mostafa Nakhaei, Koorosh Naderi et al.Properties such as durability and moisture resistance of asphalt concrete significantly improve pavement service life. When siliceous aggregate is used, then preventing moisture damage and stripping become distinctly required. Typically, stripping could be prevented by either using antistripping agents or by modifying the binders. The anti-stripping agent achieve its purpose by changing the aggregates' affinity for water through changing the … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 3 Apr 2018 · 9,380 accessesView PDFCite
EditorialOpen accessIn the abstractCommentary-How do we Improve Training for Receptor Research?Marilee Ann BenoreThis issue of the American Journal of Biochemistry and Biotechnology features articles about receptor-ligand interactions that are critical to the wellbeing of all living organisms. The importance of the field of receptor research is supported by the large number of articles published in journals, the numerous specialty journals, the international conferences and the percentage of legal drugs on the market … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 8 Dec 2015 · 8,056 accessesView PDFCite
Research ArticleOpen accessIn the abstractHigh-Yield Production of Bioactive Flatfish (Paralichthys olivaceus) Myostatin-1 Prodomain in Escherichia coliIl Shik Shin, Hyung-Joo Jin, Jeong Hwan Kim et al.Myostatin Propeptide (MstnPro), the N-terminal part of Mstn precursor molecule, binds to Mstn and suppress its activity. Mstn is a potent negative regulator of skeletal muscle growth in many animal species, thus MstnPro has a great potential to be used as an agent to enhance skeletal muscle growth in animal species. Bioactive fish Myostatin-1 Propeptide (Mstn1Pro) proteins were recently expressed … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 8,012 accessesView PDFCite
Research ArticleOpen accessIn the abstractModulation of the GABAA Receptor by Srif in Rat ThalamusFatiha Chigr, Mariama El Ouahli, Ghizlane Er-Raoui et al.Somatostatin has been reported to modulate GABAA receptor complex in many brain structures. This study was conducted to investigate somatostatin modulation of the GABAA receptor binding in several rat diencephalic structures, focusing primarily on the thalamus, as this structure plays important roles. Animals were assigned to control conditions. Changes in specific binding of GABAA receptor as labelled with [35S]t-Butylbicyclophosphorothionate (TBPS) … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 6,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 8,999 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Compounds Screening from Zingiberaceae Family as Influenza A/Swine Flu Virus Neuraminidase Inhibitor through Docking ApproachUsman Sumo Friend Tambunan, Fadilah, Arli Aditya ParikesitProblem statement: Influenza A/H1N1 is a disease caused by infection of influenza a virus subtype H1N1. It is a major health problem in tropical and subtropical countries. This virus constantly mutates and consequently will be developed into new drug-resistant strains. Approach: In this research, we have conducted docking study to screen bioactive compounds from Zingiberaceae family, which has a role … …OnLine Journal of Biological Sciences, Vol. 10, Issue 4 · 31 Dec 2010 · 8,616 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Temperature and Precipitation on Global Mangrove Rhizophora Species DistributionAroloye O. Numbere, Gerardo R. CamiloClimate change influences the distribution of mangroves towards tropical or temperate regions of the world. We hypothesized that Rhizophora species organized along complex spatial and temporal temperature and precipitation gradient. To determine the affinity of different mangroves with climatic parameters, the response of eight Rhizophora species to seven climatic parameters (i.e., annual mean temperature, annual precipitation, maximum temperature of warmest … …American Journal of Environmental Sciences, Vol. 13, Issue 5 · 5 Oct 2017 · 8,259 accessesView PDFCite
Research ArticleOpen accessIn the abstractReconceptualization of Glossalgia Issue, Solution ApproachesAlexei Valerievich Yumashev, Irina Mikhailovna Makeeva, Alexander Grigorievich Volkov et al.The article discusses current therapeutic trends in glossalgia treatment, clinical experimental justification of mesodiencephalon modulation as an effective physiotherapy method with regard to the above abnormality. The principal research method is a clinical experimental one. Major trends in glossalgia treatment have been marked out in the course of scientific search and analysis of theoretical data. Most common physiotherapy methods applied … …American Journal of Applied Sciences, Vol. 13, Issue 11 · 21 Nov 2016 · 7,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractDouble Application of Translocator Protein Ligands and RAW Cells Inflammatory MilieuMaria Staykova, Filomena Mattner, David Linares, Andrew KatsifisLigands targeting the translocator protein exhibit a variety of anti-inflammatory and neuroprotective properties. A double application of eight translocator protein ligands to activated murine macrophage-like cells changed to a different extent the levels of secreted reactive nitrogen intermediates, pro- and anti-inflammatory cytokines. To our knowledge this is the first report suggesting that multiple applications of different translocator protein ligands may … …American Journal of Immunology, Vol. 12, Issue 3 · 28 Aug 2016 · 6,942 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Biological Evaluation of 6-Hydroxy-4-Methyl-5,7-(Bis-p-ChlorophenylAzo) CoumarinDalal M. Ibrahim, Juliana Jumal, Farah Wahida Harun6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarinhas been synthesized and characterizedby CHN elemental analysis, FTIR, 1H-NMR-spectroscopy andmass-spectral data. Cytotoxic screening by MTT assay was carried out on the compoundagainst breast cancer cells. The overall results from preliminary screeningprogram revealed that the cell proliferation was highly inhibited by 6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarin with the value of 2.81%, at concentration of 30 µg mL-1 comparedwith the untreated control cells and also … …American Journal of Applied Sciences, Vol. 13, Issue 1 · 21 Dec 2015 · 7,670 accessesView PDFCite