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241 results for “In Vitro Study”

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Research ArticleOpen accessAll words, across the recordTetrastigma hemsleyanum Diels et Gilg Roots from Different Origins: Pharmacognostical Identification, Content Determination of Functional Composition and in vitro Antioxidant ActivityGuang Mei Li, Jian Ge, Yongli Zheng et al.Tetrastigma hemsleyanum Diels et Gilg (T. hemsleyanum) is a unique and rare Chinese medicinal herb mainly distributed in the south of the Yangtze River in China. In the present study, T. hemsleyanum roots from seven different sites in the south of the Yangtze River (Guangxi [Baise, Guilin, and Hechi], Hunan [Fenghuang], and Zhejiang [Hangzhou, Taizhou, and Wenzhou] provinces) were collected, … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 23 Feb 2023 · 5,722 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordInvestigation of the Contribution of Late Embryogenesis Abundant (LEA) K Peptide in Enhancing the Expression of Lipase from Sphingobacterium sp.: In vitro and in Silico StudiesIbrahim Muhammad et al.Sphingobacterium sp. AB3 lipase is a psychrophilic enzyme with optimal lipolytic activity at pH 7 and 15°C. The cold-adapted properties of the lipase render it suitable for various low-temperature industrial applications such as biodiesel production, detergent formulation, and non-thermal food processing. Recent studies have shown that co-expression of LEA K peptide with AB3 lipase resulted in enhanced protein expression in … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 21 Nov 2024 · 4,569 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordThrombophilic Genes Mutations in Women with Repeated In-Vitro Fertilization FailureNaglaa Fathy Al Husseini, Ahmad Y. Rezk, Mosad M. Odah et al.Problem statement: Thrombophilia has been recently implicated in early pregnancy loss and IVF implantation failure, by impairing the initial vascularization process occurring at implantation, which is necessary for a successful pregnancy. Approach: The aim of this study is to assess the presence possibility of mutation in thrombophilic genes [Factor V (FV) gene, Prothrombin (PT) gene and Methylenetetrahydrofolate Reductase (MTHFR) gene] … …Current Research in Medicine, Vol. 2, Issue 1 · 29 Mar 2011 · 7,662 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordIn vitro Antioxidant and Cytoprotective Potentials of Postbiotic ProbioMETA G55Xinyi Song, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimStudies have demonstrated the favorable beneficial impact of probiotic metabolites on the skin. However, the use of postbiotics for skincare is a relatively new field despite their high safety and stability, which guarantee a longer shelf life. The postbiotic ProbioMETA G55(G55) is a skincare raw material, but none of the studies have evaluated the antioxidant capacity of G55 in skin … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 7 Aug 2023 · 4,953 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordAssessment of the Annona muricata Leaf Ethanol Extract Effect on The Diameter of Pancreatic Islets in Alloxan-Induced MiceSyafira N. Dewi, Supri I. Handayani, Marini Stephanie et al.Diabetes mellitus is one of a non-communicable disease whose prevalence continues to increase from year to year in both developed and developing countries. In Indonesia, it is estimated that 12 million people aged ≥15 years old had diabetes mellitus in 2013. Treatment of diabetes mellitus by using plant extract has been reported to have good results. One of the plants … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 9 Mar 2020 · 8,061 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordComputer Aid Screening for Potential Antimalarial Choroquinone Compounds as Covid 19 Utilizing Computational Calculations and Molecular Docking StudyAsmaa Aboelnaga, Asmaa M. Fahim, Taghreed H. EL-SayedClick reaction of 4,7-dichloroquinoline (1) with thiosemicarbazide (2) to afford the corresponding 2-(7-chloroquinolin-4-yl)thiosemicarbazide (3) utilized ultrasonic irradiation which can cyclized easily with ethylacetoacetate to give the 3-(7-chloroquinolin-4-ylamino)-tetrahydro-6-methyl-2-thioxopyrimidin-4(1H)-one (4) via nucleophilic substitution reaction. The synthesized compounds was examined in vitro antimalarial activity with IC50 = 11.92, 25.37 μg/mL against chloroquinone drug. Furthermore, the theoretical investigation of most active compounds CQT and … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 30 Nov 2020 · 6,568 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordIn Vitro Biological Profiles and Chemical Contents of Ethanolic Nest Entrance Extracts of Thai Stingless Bees Tetrigona apicalisTouchkanin Jongjitvimol, Sathirapong Kraikongjit, Pussadee Paensuwan, Jirapas JongjitwimolTetrigona apicalis is a species of stingless bees found in Lower Northern Thailand. They normally construct their nest entrances as an external structure for protecting themselves from enemies. Their biological properties have not well characterized yet. The objectives of this study were to evaluate the antibacterial, antifungal and anti-proliferative activities of their nest entrances. Samples were collected from four provinces … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 2 Nov 2020 · 6,781 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordResponse of Different Agrobacterium Rhizogenes Strains for in vitro Hairy Root Induction and Accumulation of Rosmarinic Acid Production in Agastache RugosaWoo Tae Park, Thanislas Bastin Baskar, Sun Kyung Yeo et al.In this study a total of seven different Agrobacterium rhizogenes strains were evaluated for their ability to transform the plant Agastache rugosa and to produce the secondary metabolite rosmarinic acid. All the strains of A. rhizogenes i.e., 13333, 15834, A4, LBA9402, R1000, R1200 and R1601 strains tested here in this study, were able to induce hairy root formation in leaf … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 3 Sep 2017 · 7,866 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEnhancement Effect of BAP and Spent Mushroom Compost in Micro-Propagation of Sabah Snake GrassWan Nurul Hidayah Wan Anuar, Suat-Hian Tan, Siti Hamidah Radiyah Shiekh Mahmud et al.Medicinal plants which is Clinacantus nutans (C. nutans) that known as Sabah Snake Grass or Belalai Gajah can treat several diseases including cancer. In order to provide and grow this plant in large number for health and pharmaceutical industry, one of the solutions is through the plant tissue culture technique. In this experiment, C. nutans was cultured under controlled conditions … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 31 Oct 2019 · 8,193 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordInhibition Effect of Walnut Leaf Polysaccharide on HepG2 Cells in vitroShuqing Yang, Haifang Xiao, Shuyan Yu et al.In this study, the effect of Walnut Leaf Polysaccharides (WLP) on human liver tumor HepG2 cells was investigated. The results showed that WLP had dose-dependent and time-dependent inhibitory effects on HepG2 cell viability. Typical apoptosis characteristics were observed in WLP-treated HepG2 cells through 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethyl-benzimidazolyl-carbocyanine iodide (DAPI) staining and Acridine Orange (AO)/Ethidium Bromide (EB) dual staining. Meanwhile, significant decrease in Mitochondrial … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 4 · 29 Oct 2019 · 7,313 accessesView PDFCite