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Research ArticleOpen accessIn the abstractCLASSIFICATION OF MICROCALCIFICATION BASED ON WAVE ATOM TRANSFORMA. Rajesh, Mohan EllappanBreast cancer is a serious problem for women in the world. It is the most common form of cancer diagnosed in woman, with one in nine women expected to be diagnosed with some form of cancer in their life-time. It is second only to lung cancer in cancer related deaths. Statistics shows that the case of breast cancer in the … …Journal of Computer Science, Vol. 10, Issue 8 · 5 Apr 2014 · 6,517 accessesView PDFCite
Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Overview of Malaria ControlEmmanuel Chanda, Mulakwa Kamuliwo, Richard W. Steketee et al.Malaria remains a serious global public health problem and a leading cause of morbidity and mortality in sub Saharan Africa. In Zambia the disease is endemic with stable transmission, accounting for 40% of all out-patient attendances and is responsible for 20% deaths among children under five. Scaling up of scientifically proven high impact preventive, curative and supportive interventions and deploying … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Apr 2013 · 7,960 accessesView PDFCite
Research ArticleOpen accessIn the abstractConcentration-Effect, Incidence and Mechanism of Nevirapine HepatotoxicityAdikwu Elias, Brambaifa NelsonNevirapine is a dipyridozepinone non nucleoside reverse transcriptase inhibitor approved for use in HIV-infected patients. Its efficacy has been well demonstrated in numerous clinical trials. It has activity against HIV-1 but does not have significant activity against HIV-2 or other retroviruses. Nevirapine is used as one of the components of highly active antiretroviral therapy in HIV patients and in the … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 19 Apr 2013 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropharmacological Assessment of an Aqueous Bark Extract of Antiaris toxicaria (Pers.) Lesch. (Moraceae) in RodentsPriscilla K. Mante, Donatus W. Adongo, Kennedy K.E. Kukuia et al.Antiaris toxicaria is a plant traditionally used in Ghana for the treatment of various neurological conditions such as epilepsy and pain. This present study therefore seeks to screen for the neuropharmacological activities of the aqueous extract of Antiaris toxicaria (AAE) stem bark. The effect of Antiaris extract on pentobarbital-induced sleeping time, tail immersion test, spontaneous locomotor activity, motor coordination, PTZ-induced … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 4 · 27 Nov 2012 · 7,794 accessesView PDFCite
Research ArticleOpen accessIn the abstractPlasmodium Pre-Erythrocytic Stages: Biology, Whole Parasite Vaccines and Transgenic ModelsKota Arun Kumar, Satish MishraMalaria remains one of the world’s worst health problems, which causes 216 million new cases and approximately 655,000 deaths every year WHO World Malaria Report, 2011. Malaria transmission to the mammalian host is initiated through a mosquito bite that delivers sporozoites into the vertebrate host. The injected sporozoites are selectively targeted to liver which is the first obligatory step in … …American Journal of Immunology, Vol. 8, Issue 3 · 13 Sep 2012 · 8,263 accessesView PDFCite
Research ArticleOpen accessIn the abstractGanoderma Species Associated with Basal Stem Rot Disease of Oil PalmLing-Chie Wong, Choon-Fah J. Bong, A. S. IdrisProblem statement: Basal Stem Rot disease (BSR) is one of the most serious diseases that have been causing major losses in the oil palm industry in Southeast Asia, especially in Malaysia and Indonesia. Several species of Ganoderma have been reported pathogenic to oil palm, however, the diversity and differentiation of the Ganoderma species were not widely studied and the identity … …American Journal of Applied Sciences, Vol. 9, Issue 6 · 19 Mar 2012 · 9,631 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,430 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cardioprotective Diet in Acute Coronary SyndromeR. B. Singh, Suniti Dharwadkar, Fabien DeMeester et al.Problem statement: Nutritional factors appear to be quite important in the pathogenesis and prognosis among patients of Acute Myocardial Infarction (AMI) or Acute Coronary Syndrome (ACS). Increased consumption of proinflammatory foods; such as refined starches and sugar, trans fat, saturated fat and w-6 fatty acids may increase proinflammatory cytokines, oxidative stress and free fatty acids causing endothelial dysfunction. Approach: Columbus … …Current Research in Medicine, Vol. 2, Issue 2 · 15 Oct 2011 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,211 accessesView PDFCite