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Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Renoprotective Effects of Valsartan in Methotrexate-Induced Acute Kidney Injury in RatsDina KutbiMethotrexate (MTX) is a widely used chemotherapeutic agent known for its nephrotoxic effects, which can lead to acute kidney injury in hospitalized patients. However, the mechanism by which MTX induces nephrotoxicity is not entirely clear, but it is believed to involve oxidative stress and direct toxic effects on renal tubules. Valsartan, an angiotensin II receptor blocker, has been shown to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 4 May 2024 · 4,571 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptic Neuropathy: Characteristic Pathology for Identifying Drugs with Potential to Cause Mitochondrial ToxicityConnor Dyer, Katlyn Droke, Ugne Zekonyte, Mariana RoscaDeleterious effects on mitochondria are known to be frequently caused by prescription drugs, however, there is no standard and specific testing by pharmaceutical companies on these effects on mitochondria during drug development. The objective of this study is to determine if cases of optic neuropathy are related to drug-induced mitochondrial toxicity in a way that could be used to predict … …American Journal of Pharmacology and Toxicology, Vol. 18, Issue 1 · 19 Jan 2024 · 8,562 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Review ArticleOpen accessIn the abstractUse of Entomopathogenic Fungi as Biopesticides to Manage Insect Pest: A ReviewAnthony Emaru, Jane Gesimba Nyaanga, Saidi MwanarusiEntomopathogenic Fungi (EPF) biopesticides are more environmentally friendly and are an alternative to toxic synthetic chemicals. Due to EPF's pathogenic nature to various arthropod pests, it is thus considered a primary candidate for an integrated biological approach due to its numerous invaluable effects. However, an urgent need is to develop an environmentally safer, more sustainable, and practical approach to managing … …American Journal of Applied Sciences, Vol. 21, Issue 1 · 12 Jul 2024 · 8,015 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Exposure of Pesticides to Honeybees: A Global Threat to Food SecurityHalima Sadia, Pratik Raj Karki, Mansura Afroz et al.The pivotal role of honeybees as global pollinators underscores their significance in ecological and agricultural systems. However, the beekeeping industry faces a significant challenge due to the improper utilization of pesticides, resulting in adverse effects on honeybee populations. This comprehensive review endeavors to investigate the toxicity of pesticides to honeybees, examining the various routes of exposure. Furthermore, it aims to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 20 Jan 2024 · 6,058 accessesView PDFCite
Research ArticleOpen accessIn the abstractParacetamol: A Focus on DogsCharbel Fadel, Irene Sartini, Mario GiorgiParacetamol (APAP) is an aniline analgesic, antipyretic and non-narcotic. It is an essential drug, widely used in human medicine. In veterinary medicine it has an extra label use in many countries. It is used exclusively in some animals, including dogs. It has a mechanism of action similar to that of NSAIDs, as well as other unique characteristics. A variety of … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 4 · 2 Nov 2021 · 11,585 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Chichorium intybus Extract Against Renal Toxicity Induced by Magnetite Silver Nanoparticles in Male RatsDoha M. Beltagy, Ehab Tousson, Nabiha I Abdo, Batoul M. IzzularabMagnetite silver nanoparticles (Fe3O4/AgNPs) symbolize a new candidate in several industrial and biological products for their activities, simple preparation and low synthesis costs. Many studies recommended the usage of Fe3O4/AgNPs to overcome lacking biocompatibility of AgNPs inside the body. However, Fe3O4/AgNPs also has toxic effects on kidney tissues. In this study, AgNPs was synthesized on the surface of magnetic nanoparticles … …OnLine Journal of Biological Sciences, Vol. 21, Issue 3 · 15 Sep 2021 · 6,318 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Crassocephalum bauchiense Ethanolic Extract on Reproductive Parameters in Rabbit Does Exposed to Potassium DichromateChongsi Margaret Mary Momo, Manfo Tsague Faustin Pascal, Nyambi Pasima et al.The present study was undertaken to evaluate the effects of Hutch leaves Ethanolic Extract (EE) on reproductive parameters, toxicity biochemical markers and oxidative stress indicators in does exposed to Potassium Dichromate (PD). Thirty-six nulliparous sexually mature does of eight months; weighing 2.80-3.00 kg were divided into six groups of six animals, comparable in terms of Body Weight (BW). After mating, … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 2 · 19 May 2021 · 6,819 accessesView PDFCite