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29 results for “potential biomarkers”
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Research ArticleOpen accessIn the abstractDifferential Expression of Cellular and Exosomal MicroRNA Isolated from Oral Cancer Cells and their Resistance to ChemotherapyBrady Petersen, Carl Yu, Samuel Hutchings et al.MicroRNAs are abundant small non-coding RNA with a variety of known functions, including transcriptional activation and inhibition. Recent evidence has suggested that microRNA expression may influence the responsiveness of some cancers to chemotherapy, including liver and lung cancers. Some evidence has now suggested that specific microRNAs, such as miR-21, miR-155, and miR-375, may influence oral cancer responsiveness to chemotherapy – … …Current Research in Dentistry, Vol. 13, Issue 1 · 29 Jul 2022 · 5,906 accessesView PDFCite
Review ArticleOpen accessIn the abstractA Review of Technological Progression from Radiomics to Breathomics for Early Detection of Lung CancerFunmilayo S. Moninuola, Oluwadamilola Oshin, Emmanuel Adetiba et al.Lung Cancer (LC) is formed by an uncontrolled growth of abnormal cells in the lungs, which alters the body's metabolism. Early detection of LC is very important for a better survival rate and prognosis in patients and persons at risk of the disease. Traditional approaches to LC detection are less sensitive to cancerous cells at the early stage, are invasive … …Journal of Computer Science, Vol. 17, Issue 11 · 26 Nov 2021 · 6,264 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Vascular Endothelial Growth Factor (VEGF) on Dental Pulp Stem Cells (DPSC)Eric Mullins, Cale Forgues, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. Studies of DPSC differentiation have demonstrated the potential to form many tissue types, including neural, osteogenic and vascular precursors using cytokines and growth factors, such as Vascular Endothelial Growth Factor (VEGF). Eight previously isolated Dental Pulp Stem Cell (DPSC) … …Current Research in Medicine, Vol. 9, Issue 1 · 1 Jun 2019 · 13,835 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Identification of Oral Cancer Stem Cells (CSC) within Commercially Available Cell LinesRobert Chauncey, Kai Hatch, Toni Jilka et al.Previous studies have demonstrated some tumors develop or maintain a small sub-population of cells with stem cell-like properties. This Cancer Stem Cells (CSC) may exhibit differential properties that allow their escape from traditional radiation or chemotherapy treatments and may therefore be responsible for cancer recurrence. Few studies have explored this phenomenon among oral cancer cell lines, therefore the objective of … …Current Research in Dentistry, Vol. 9, Issue 1 · 2 Jun 2018 · 12,722 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,761 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractNovel Biomarkers in Determining Prostate Cancer Diagnosis and PrognosisZuzana Varchulova Novakova, Katarina Bevizova, Iveta GasparovaThe clinical behavior and molecular pathology of prostate cancer is highly variable. Current "traditional" prognostic markers cannot reliably distinguish the potentially life-threatening cancer from indolent cancer. Identification of additional new predictors of cancer aggressiveness is therefore urgently required. This communication is aimed at a brief review of new biomarkers in prostate cancer diagnostics and prognostics. Pubmed systematic search was performed … …OnLine Journal of Biological Sciences, Vol. 14, Issue 4 · 14 Jan 2015 · 6,905 accessesView PDFCite
Research ArticleOpen accessIn the abstractSerum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet BAhmad Taha Khalaf, Yan YuehuaAlthough it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying … …American Journal of Applied Sciences, Vol. 11, Issue 12 · 6 Jan 2015 · 6,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractToxicological Consequences of Di-N-Butyl-Phthalate (DBP) on Health of Nile Tilapia FingerlingsEhsan H. Abu Zeid, Al Shimaa A. KhalilPhthalic Acid Esters (PAEs) are mainly used in the plastics industry as adhesives and plasticizers. Di-n-Butyl Phthalate (DBP) is one of the important members in the family of PAEs was listed as environmental priority pollutants by the US Environmental Protection Agency. The objective of this study was to evaluate the toxicological consequences in Nile Tilapia Oreochromis niloticus L. fingerlings, exposed … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 8,469 accessesView PDFCite
EditorialOpen accessIn the abstractNanotechnology: Engineering Materials for a Better 21st CenturyMeng Qiao, Xiyun Liu, Lei ZhangToday, we are living in the midst of a technological revolution, where nanotechnology is demonstrating a greater commitment to make people’s everyday lives better. The aim of nanotechnology is to create new materials with desired properties by engineering their nanoscale structures and components. One of the most important impacts of nanotechnology is in medical diagnosis and treatment. Cardiovascular diseases such … …Current Research in Nanotechnology, Vol. 5, Issue 1 · 26 Nov 2014 · 8,743 accessesView PDFCite