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28 articles for “oxidative stress markers”
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Research ArticleOpen accessIn the abstractThe Role of Nf-Kappa and HDCA and Implication of Oxidative Stress in Airway Inflammation of Chronic Obstructive Pulmonary DiseaseGhada A. Abdallah, Nevine M. Abd-Elfattah, Hala M. Ghanem et al.Oxidative stress has been implicated in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD), due to its effect on proinflammatory gene transcription. Oxidants/antioxidants imbalance is responsible for disease development. The study was designed to assess oxidative stress and inflammation in COPD patients. The level of TNF-α and IL-8 in sputum and BAL were compared. NF-κB and HDAC were measured in … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 4 Dec 2014 · 6,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractREMEDIAL EFFECTS OF VITAMIN E AND L-ARGININE ON PERIPHERAL NEUROPATHY IN STREPTOZOTOCIN-INDUCED DIABETIC RATSIsmaeel Bin-Jaliah, Samah El-Attar, Eman F. Khaleel et al.It was shown that hyperglycemia in diabetic patients is the main factor of diabetic peripheral neuropathies. Various pathways related to oxidative stress, vascular defect and defective endothelium dependent relaxation have been implicated in the development of diabetic peripheral neuropathy. A substantial number of studies have shown that antioxidant treatment are promising therapeutics that can prevent or correct reduced motor nerve … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 23 Dec 2013 · 8,044 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Virgin Olive Oil (Olea europea. L) on Kidney Function Impairment and Oxidative Stress Induced by Mercuric Chloride in RatsYoucef Necib, Ahlem Bahi, Sakina Zerizer et al.The study was designed to investigate the possible protective role of virgin olive oil in mercuric chloride induced renal stress, by using biochemical approaches. The effects of virgin olive oil on mercuric chloride induced oxidative and renal stress were evaluated by serum creatinine, urea and uric acid levels, kidney tissue lipid peroxidation, GSH levels, GSH-Px and GST activities. Administration of … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 16,791 accessesView PDFCite
Research ArticleOpen accessIn the abstractHYPOGLYCEMIC, HEPATO-RENAL AND ANTIOXIDANT POTENTIAL EFFECTS OF CHAMOMILE RECUTITA FLOWERS ETHANOLIC EXTRACT IN STREPTOZOTOCIN-DIABETIC RATSHassan Al-Musa, Fahaid AL-HashemThis study was undertaken to evaluate the hypoglycemic and hepatorenal protective effect of ethanolic extract of Chamomile recutita flowers in streptozotocin-Diabetic Rats. Before the beginning of the experiments, acute and subacute studies were carried out in control animals first to investigate the LD50 of this extract. In the experimental design, adult male albino rats were divided into five groups: (1) … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 9 Dec 2013 · 8,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Thai Style Stretching Exercise on "Ruesi Dud Ton" on Physical Health and Oxidative Stress in Healthy VolunteerJintanaporn Wattanathorn, Tasanee Boonterm, Wipawee Thukhummee et al.Despite the health benefit reputation of Thai stretching exercise "Ruesi dud ton", no scientific evidence is available. Therefore, we aimed to determine the effect of Thai style stretching exercise on physical health and oxidative stress markers including Malondialdegyde (MDA) level and the activities of main scavenger enzymes including Superoxide Dismutase (SOD), Catalase (CAT) and Glutathione Peroxidase (GSH-Px). We had determined … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 22 Feb 2013 · 7,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa Oleifera Lam Mitigates Oxidative Damage and Brain Infarct Volume in Focal Cerebral IschemiaWoranan Kirisattayakul, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Problem statement: At present, the therapeutic outcome of cerebral ischemia is still not in the satisfaction level. Therefore, the preventive strategy is considered. Based on the protective effect against oxidative damage of Moringa oleifera Lam. Leaves extract, we hypothesized that this plant extract might protect against cerebral ischemia, one of the challenge problems nowadays. In order to test this hypothesis, … …American Journal of Applied Sciences, Vol. 9, Issue 9 · 3 Aug 2012 · 7,576 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa oleifera Leaves Extract Attenuates Neuropathic Pain Induced by Chronic Constriction InjuryJurairat Khongrum, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Problem statement: Neuropathic pain, a challenge of this decade, has been reported to be associated with the diversity conditions including diabetes. At present, there are no conventional analgesics that can effectively treat neuropathic pain with a satisfactory outcome. Due to the limitation of therapeutic efficacy, the searching for novel effective remedies in the management of neuropathic pain is required. Approach: … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 18 Jun 2012 · 17,253 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Functional Effect of Kaempferia Parviflora on Ischemic Stroke in RatsWathita Phachonpai, Sinthuporn Maharun, Terdthai Tong-Un et al.Problem statement: Oxidative stress has been implicated as important factors in the pathogenesis of cerebral ischemia-induced behavioral deficits particularly memory. Growing attention is being paid to traditional medicinal plants possessing antioxidant activity, as they have been proved therapeutically/prophylactically fruitful against stroke condition. Present study provides evidence of the neroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, against … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 2 · 16 Mar 2012 · 8,742 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiomarkers of Oxidative DNA Damage and Soluble Fas/Fas Ligand in Type 2 Diabetic PatientsMohamed H. Mahfouz, Ibrahim A. Emara, Ghada A. OmarProblem statement: Involvement of oxidative stress in the pathogenesis of diabetic complications has been proposed. 8-hydroxy-2'-deoxyguanosine (8-OHdG) has been reported to serve as a new sensitive biomarker of the oxidative DNA damage in vivo. Apoptosis via Fas/Fas Ligand (FasL) interactions has been proposed to be a major T-cell-mediated effector mechanism in autoimmune diabetes. This study was undertaken to investigate whether … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 3 Feb 2012 · 7,110 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of L-Carnitine and Cinnamon Extract Treatment on Lens Crystallins of Rats Fed High Fructose DietMohamed H. Mahfouz, Amany Abd El-Ghaffar, Mona A. Mohamed, Hala M. GhanemProblem statement: Rats fed high dietary fructose are documented to form an acquired model of insulin resistance; the present study aims to investigate possible changes in lens crystallins of rats fed high fructose diet and the effects of administration of each exogenous L-Carnitine (CA) and Cinnamon Extract (CE) on protein glycation, oxidative stress and redox homeostasis in this rat model. … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 3 Aug 2011 · 8,716 accessesView PDFCite