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40 articles for “multidrug resistant”

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Research ArticleOpen accessIn the keywordsOutcomes and Risk Factors Associated with Drug Resistant Tuberculosis in Rural Eastern Cape, South AfricaCarine Bokop Fotso, Sandeep D. Vasaikar, Teke ApalataWith the emergence of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) strains of Mycobacterium tuberculosis, Tuberculosis (TB) has become an even greater threat in South Africa (SA). The study sought to investigate the resistance pattern of anti-TB drugs in M. tuberculosis as well as to determine the associated risk factors and outcomes for MDR-TB and XDR-TB. A descriptive study was conducted … …American Journal of Infectious Diseases, Vol. 14, Issue 2 · 15 Aug 2018 · 9,536 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPrevalence and Antibiotic Sensitivity test of Salmonella Serovars from Enteric Fever Suspected Patients Visiting Alka Hospital, LalitpurKalpana Pandey, Vijay K. Sharma, Roshani MaharjanEnteric fever is still an important public health problem in developing countries including Nepal. A changing antibiotic susceptibility pattern of Salmonella Typhi and Salmonella Paratyphi A has increased to a great concern. To determine the prevalence and antibiotic sensitivity pattern of S. enteric serovars Typhi and Paratyphi from blood specimen in enteric fever suspected culture positive cases. A cross-sectional study … …Current Research in Microbiology, Vol. 6, Issue 2 · 30 Oct 2015 · 7,952 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,211 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence and Determinants of Antibiotic Use by the Elderly in Marrakech, MoroccoNaima Aoutil, Mohamed Cherkaoui, Mohamed BouskraouiAntibiotics are essential for the prevention and treatment of bacterial infections; however, their inappropriate use among elderly populations poses serious risks, including the emergence of multidrug-resistant organisms. Antimicrobial resistance has become a critical global public health challenge, with irrational antibiotic use being one of its primary drivers. In Morocco, data on antibiotic use among older adults remain scarce, particularly regarding … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 13 Apr 2026 · 1,365 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy of Ageratum conyzoides L. (Asteraceae) Phytochemical Composition as Quorum-sensing Inhibitors to Combat Antibiotic-resistant Bacterial InfectionsEli Compaoré, Lassané Ouedraogo, Ablassé Rouamba et al.The rise of antibiotic-resistant bacterial infections has intensified the search for plant-derived quorum-sensing (QS) inhibitors as alternative therapeutic strategies. Ageratum conyzoides L. has a long history of traditional use as an antimicrobial agent against multidrug-resistant pathogens, yet the phytochemical basis of its QS-inhibitory activity remains incompletely characterized. This study aimed to investigate the phytochemical composition of A. conyzoides and evaluate … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,772 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of Diagnostic Tests for Fosfomycin Resistance Detection in Clinically Significant EnterobacteralesSantoshi Maruti Naik, Biranthabail Dhanashree, Himani KotianMultidrug resistance in Enterobacterales has triggered interest in old antibiotics like fosfomycin. Various methods to determine fosfomycin resistance are time-consuming and yield unpredictable results. Hence, the study was undertaken to compare the rapid fosfomycin NP test with the recommended agar dilution test and few other tests. In this cross-sectional, time-bound, prospective study, Enterobacterales (N = 110) were tested for their … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 21 Nov 2025 · 2,113 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Evaluation of Synergistic Antibacterial Effects in Blended Essential Oil against Gram-Positive and Gram-Negative PathogensMin-Gi Kwon, Jae Kyung KimThe rising emergence of multidrug-resistant bacteria has heightened the search for novel antibiotic agents. Essential Oils (EOs) are complex combinations of volatile organic compounds generated by plants, with many exhibiting significant antimicrobial properties. This study evaluates the antibacterial movement of single and blended EOs against representative gram-positive bacteria Staphylococcus aureus and Methicillin-Resistant S. aureus (MRSA) and gram-negative bacteria Escherichia coli … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 7 Jul 2025 · 5,481 accessesView PDFCite
Research ArticleOpen accessIn the abstractWound Healing Activity of Chlorogenic Acid in Diabetic Rats is Mediated Through Antibacterial, Antioxidant, and Proliferative EffectsAbdullah Abdulrahman Al-Ghanayem, Mohammed Sanad Alhussaini, AbdulRahman Abdulla Ibrahim Alyahya et al.Chlorogenic acid is known to have antibacterial action against a number of pathogens. This study provides insights into the potentiality of chlorogenic acid in the treatment of chronic infection in wounds. The anti-infective and healing effect of chlorogenic acid in infected wounds was evaluated using diabetic rats. Antibacterial activity of chlorogenic acid against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Multidrug-Resistant (MDR) … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 21 Jan 2024 · 6,154 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence and Genotypic Analysis and Antibiotic Resistance of Salmonella Species Isolated from Imported and Freshly Slaughtered ChickenWael K. Elfeil, Mahmoud E. Ezzat, Amira Fathi et al.Salmonellosis is a bacterial disease caused by different types of Salmonella species and associated with clinical disease in both human, birds and livestock species. Salmonellosis associated with severe economic impacts either from losses in poultry farm due to pathological picture losses, cost of medication, condemnation in slaughterhouse or zoonotic important. This study focused on the prevalence of Salmonellae in imported … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 2 · 28 May 2020 · 6,986 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Diversity and Drug Resistance of Mycobacterium tuberculosis Complex Isolates and Nontuberculous Mycobacteria Identification from Presumptive Tuberculosis Cases in Oaxaca, MexicoNakamura-Lopez Yuko, Valencia-Carmona Oscar Daniel, Martinez-Cruz Perla Monica et al.Tuberculosis (TB) is a re-emerging health problem worldwide. In Mexico, information about genetic diversity and drug resistance of Mycobacterium Tuberculosis complex (MTBc) is limited. Samples from 463 Presumptive TB cases were tested for TB by smear, culture and PCR, from which 19.2% were identify as MTBc and 16% as nontuberculous mycobacteria. MTBc isolates were characterized by Large Sequence Polymorphisms (LSPs), … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 9 Feb 2020 · 7,159 accessesView PDFCite