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Research ArticleOpen accessIn the keywordsPreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,397 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDiagnostic Value of Serum and Cerebrospinal Fluid Procalcitonin in Differentiation Bacterial from Aseptic MeningitisZhinous Bayat Makoo, Hamid Reza Soltani, Akbar Hasani et al.Problem statement: Acute bacterial meningitis is one of the most important causes of medical emergency diseases, which can cause high mortality and morbidity rates. Early antibiotic therapy is life saving in bacterial meningitis. One of the most common etiologies of acute meningitis is viral. Differentiation between bacterial and Aseptic meningitis is mandatory, which leads to avoid useless administration of antibiotics. … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 12,078 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of Vitamin A on Growth Performance, Antioxidant Status and Blood Constituents in Lactating Grey GoatWeiren Yang, Ping Wang, Yuanqiang Jing et al.Problem statement: It is regarded that vitamin A protects cells from damage by radicals which are believed to contribute to certain chronic diseases and regulates immune function of animals by protection of mucosal epithelium acting as the first defense barrier. All these properties of vitamin A may be attributable to its antioxidant activity. This study was to evaluate the effects … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 4 · 27 Dec 2010 · 7,674 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPathophysiology of Adipocyte Defects and Dyslipidemia in HIV Lipodystrophy: New Evidence from Metabolic and Molecular StudiesAshok Balasubramanyam, Rajagopal V. Sekhar, Farook Jahoor et al.Despite a burgeoning mass of descriptive information regarding the epidemiology, clinical features, body composition changes, hormonal alterations and dyslipidemic patterns in patients with HIV lipodystrophy syndrome (HLS), the specific biochemical pathways that are dysregulated in the condition and the molecular mechanisms that lead to their dysfunction, remain relatively unexplored. In this paper, we review studies that detail the metabolic basis … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,608 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,095 accessesView PDFCite
Research ArticleOpen accessIn the abstractsuPAR as an Inflammatory and Preclinical Atherosclerotic Marker in Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Neelam Manjunath Pawar et al.The mechanistic link between inflammation and atherosclerosis highlights the critical role of immune modulation in cardiovascular disease. The soluble urokinase plasminogen activator receptor (suPAR), an immune-derived factor, has recently emerged as a non-specific inflammatory marker across chronic diseases and infections. All cells within the atherosclerotic arterial wall can express uPAR and release urokinase, which plays a key role in the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 30 Mar 2026 · 1,122 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy of Murraya paniculata Leaf Flour in Reducing Subclinical Mastitis in Dairy Goats Fed Date Pulp-Based DietsDwierra Evvyernie, Endah Yuniarti, Rika Zahera, Anuraga JayanegaraSubclinical mastitis is a major concern in dairy production, leading to economic losses and antibiotic dependence, which poses risks of milk residue contamination. As a natural alternative, orange jasmine (Murraya paniculata) leaves, rich in flavonoids, exhibit antimicrobial and anti-inflammatory properties. This study investigated the effects of incorporating date pulp and orange jasmine leaf flour (OLF) into the diets of lactating … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 21 Feb 2026 · 1,590 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Vitamin B12 as an Anti-atherogenic and Anti-inflammatory Agent in Apparently Healthy Adults With Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Sowndarya Kollampare, Neelam Manjunath PawarVitamin B12 deficiency is associated with metabolic changes like methyl malonic acidemia and hyperhomocystinemia eventually leading to atherosclerosis. Dyslipidemia and vitamin D (vit D) deficiency are independent risk factors of CVD. This study aims to explore the interrelationship between inflammatory markers, adverse lipid profile and vitamin B12 in hypovitaminosis D. Since, atherosclerosis is an inflammatory condition we have investigated CRP … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 11 Jul 2025 · 3,326 accessesView PDFCite
Research ArticleOpen accessIn the abstractHaemato-Biochemical Indices of Red Sokoto Goats Fed Various Levels of Earthworm Meal-Based DietsMoshood Adewale Belewu, Ling Shing Wong et al.Blood is essential to life and it is vital for the transportation of oxygen from the lungs to every cell of the body for metabolism purposes. Hence, blood samples were collected from thirty (30) healthy Red Sokoto goats fed an earthworm meal-based diet with ten goats per treatment constituting a replicate in a Completely Randomized design model to evaluate the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 3 Dec 2024 · 4,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of Fig Leaf (Ficus carica L.) as Immunomodulatory Agent in vitro and in SilicoAnita Dewi, Fitri Rahmayanti, Haidar Bagir et al.Natural remedies are increasingly being used as alternatives to conventional medicine, and their popularity is growing. The fig plant (Ficus carica L.), which is known to contain secondary metabolites such as alkaloids, flavonoids, phenolics, terpenoids, steroids, and saponins, has the potential to act as an immunomodulator. The purpose of this study was to determine the content of flavonoid compounds based … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 19 Jan 2023 · 6,232 accessesView PDFCite