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204 articles for “liver”
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Research ArticleOpen accessEvery word in the titleAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,791 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Leptospirosis on the Concentrations of Streptomycin in Liver and Kidneys of PigsLabrini V. Athanasiou, Vassilios Papatsiros, George Valiakos et al.Leptospirosis is a re-emerging infectious disease with zoonotic potential. Pigs are reservoir hosts of the pathogen and streptomycin is among the antibiotics proposed to eliminate leptospiral infection. The purpose of this study was to determine streptomycin concentrations and the possible effect of the presence of Leptospira in the liver and kidneys on drug distribution. Six pigs with leptospirosis and six … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 28 Mar 2013 · 7,485 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProtection of Terminalia belerica Roxb. Against Iron Overload Induced Liver Toxicity: An Account of Its Reducing and Iron Chelating CapacityBibhabasu Hazra, Rhitajit Sarkar, Nripendranath MandalExcess iron deposition in the liver catalyses the production of Reactive Oxygen Species (ROS) which in turn initiate oxidative damage of protein and nucleic acids leading to several human diseases. The fruits of Terminalia Belerica Roxb. (TB) has been most commonly used not only in stimulating gastrointestinal health, but also in treatment of various hepatic disorders. The present study was … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 3 · 20 Nov 2012 · 7,989 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCytotoxicity Studies of Superparamagnetic Iron Oxide Nanoparticles in Macrophage and Liver CellsAroonsri Priprem, Pramote Mahakunakorn, Chunpen Thomas, Ian ThomasSuperparamagnetic Iron Oxide Nanoparticles (SPIONs) prepared by simplified coprecipitation were attractive as MRI contrast agents and drug carriers which could internally be manipulated under the influence of an external magnetic field and also cancer treatment due to additional hyperthermia effects. Problem statement: Macrophage and liver cells are potentially exposed to internal SPIONs, thus used for this cytotoxic tests for safety … …Current Research in Nanotechnology, Vol. 1, Issue 2 · 22 Jun 2011 · 11,624 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Citrullus colocynthis Pulp Extract on the Liver of Diabetic Rats a Light and Scanning Electron Microscopic StudyMohammad Khalil, Gamal Mohamed, Mohammad Dallak et al.Problem statement: The goal of the current investigation was to clarify the effects of Citrullus colocynthis pulp extract on the structure of the liver of diabetic rats at both light and scanning electron microscopic levels. Approach: Forty-eight adult male albino rats were equally allocated into four groups: Group1: control, Group 2: Citrullus colocynthis-treated, Group 3: diabetic rats and Group4: diabetic … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 3 · 30 Sep 2010 · 9,478 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleChange in Growth Performance and Liver Function Enzymes of Broiler Chickens Challenged with Infectious Bursal Disease Virus to Dietary Supplementation of Methionine and ThreonineElham Maroufyan, Azhar Kasim, Seyed Reza Hashemi et al.Problem statement: The aim of this study was to verify the effects of methionine and threonine supplementations higher than the NRC recommendation on growth performance, liver function enzymes, blood parameters and immune tissues of broiler chickens challenged with infectious bursal disease. Approach: A total of 450 day-old male broiler chicks were assigned to nine groups. Chickens were fed by three … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 9,469 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCamel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino RatsFahaid Al-HashemProblem statement: Aluminum chloride (AlCl3) is commonly used in daily life but it can be potentially toxic. Therefore, the present study was carried out to investigate the protective effects of camel’s milk against aluminum-induced biochemical alterations and oxidative stress in the liver and kidney of white albino rats. Approach: White albino male rats (230-250 g) were divided into three groups … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 10,367 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvidences of Apoptosis in Hepatitis C Virus-Infected Hepatocytes and Peripheral Blood Monocuclear Cells in the Absence of Liver InjuryViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Understanding the mechanism of Hepatitis C Virus (HCV) pathogenesis is an important part of HCV research. In this study, the presence of apoptosis in HCV-infected liver and Peripheral Blood Mononuclear Cells (PBMC) from patients positive for anti-HCV antibodies and negative for serum HCV-RNA was investigated. The samples obtained from 21 patients were studied by in situ Hybridization (ISH), Immunofluorescence, TUNEL … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,975 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSelenium Enriched Peanut Protein Alleviates Alcohol-Induced Liver Damage in Mice by Modulating the Composition of the Gut MicrobiotaLin Gao, Jiawei Yuan, Yuhuan Cheng et al.Alcohol Use Disorder (AUD) is one of leading external causes of mortality. Selenium-enriched Peanut Protein (SePP) is a type of Se compound present in Se-enriched plants. Our previous studies showed that SePP possesses potential therapeutic properties and could alleviate alcohol-induced AML-12 cytotoxicity. It spurred us to determine the underlying mechanisms and roles of SePP on gut microbiota. Here, ICR mice … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 23 Dec 2021 · 6,230 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effects of Costus Root Aqueous Extract against Schistosomiasis, Liver Damage and Oxidants in Mouse Models of Schistosoma mansoni InfectionAreej Jameel M. AlghabbanSchistosomiasis is one of the major human parasitic diseases in many developing countries that causing chronic ill health in humans. The present work aimed to study the possible curative role of Costus (Saussurea lappa) root extract against Schistosoma mansoni infection induced liver toxicity, cytokines, oxidative stress and DNA damage in mice. 40 adult male micewere divided into four groups (G1, … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 15 Apr 2021 · 6,409 accessesView PDFCite