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129 articles for “in vivo”
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Research ArticleOpen accessEvery word in the titleFACILE SYNTHESIS OF IN-VIVO INSECTICIDAL AND ANTIMICROBIAL EVALUATION OF BIS HETEROCYCLIC MOIETY FROM PET WASTEAsmaa Mahmoud Fahim, El Sayed Mohamed Yakout, Galal Abd ElMohein NawwarRecycling of Plastic Solid Waste (PSW) using green tool such as solar energy which used for degradation of plastic solid bottles (PET) to afford terepthalic acid which estrified using butanol/H2SO4 to afford dibutyl terephthalate as a starting material which has been chemically modified to yield new bis (1,2,4-triazole-3-thiol) 5, 1,3,4-oxadiazole 6, 8, 15, 1,3-thiazolidine 9, 1 H-pyrazole 10, 11 and … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 21 Aug 2014 · 7,373 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,196 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 8,999 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Vitro and In Vivo Anticancer Activity of Bacoside A from Whole Plant of Bacopa Monnieiri (Linn)N. S. Prakash, R. Sundaram, S. K. MitraProblem statement: Natural products have long been a fertile source of cure for cancer, which is projected to become the major cause of death in this century. Major classes of anticancer compounds include alkaloids, terpenoids, flavonoids and lignans. We have chosen terpenoids (bacosides) because terpenoids like taxol are currently being used in cancer chemotherapy. The anticancer activity of Bacoside A … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 1 · 7 Jun 2011 · 9,663 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory and In vivo Antiplasmodial Activities of Propolis ExtractsSyamsudin, Rita Marleta Dewi, KusmardiProblem statement: Malaria caused by various species of prozoan parasites, Plasmodium. The exact mechanism of humoral immunity in eliminating Plasmodium is not completely understood. However, an antimalarial antibody is strongly suspected to play important role in immunity. The purpose of this research was to evaluate the immunomodulator and antiplasmodial activities of Indonesian propolis extracts. Approach: Thirty male BALB/c mice weighing … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,801 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn vivo, Acute, Normo-hypoglycemic, Antihyperglycemic, Insulinotropic Actions of Orally Administered Ethanol Extract of Citrullus colocynthis (L.) Schrab PulpMahmoud Al-Khateeb, Mohammad Dallak, Fahaid Al-Hashem et al.Problem statement: Citrullus colocynthis (L.) Schrab (cucurbitaceae family) (Handal) is a fruit commonly known as bitter apple or bitter cucumber. Traditionally, Citrullus colocynthis has been used for the treatment of diabetes. In particular, the acute effect and rout of administration of ethanol extract of the seedless pulp in vivo remains untested. We investigated the effect of different routs of administration … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,306 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn vitro and In vivo Anti-Microbial Effects of Nigella sativa Linn. Seed Extracts Against Clinical Isolates from Skin Wound InfectionsMariam A. Abu-Al-BasalcProblem statement: The developing microbial resistance to the existing anti-microbial agents has become a real challenge and a serious problem facing patients suffering from skin infections. Seeds of Nigella sativa have been used for a long time in folk medicine for the treatment of such infections. Production of new potent agents is urgently needed, especially for hospitals and health centers. … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 8,924 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn vitro and In vivo Antioxidant Activity of Aphanamixis polystachya BarkAlluri V. Krishnaraju, Chirravuri V. Rao, Tayi V.N. Rao et al.Problem statement: Free radical stress leads to tissue injury and progression of disease conditions such as arthritis, hemorrhagic shock, atherosclerosis, diabetes, hepatic injury, aging and ischemia, reperfusion injury of many tissues, gastritis, tumor promotion, neurodegenerative diseases and carcinogenesis. Safer antioxidants suitable for long term use are needed to prevent or stop the progression of free radical mediated disorders. Approach: Many … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,734 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleReactive Nitrogen Intermediates Production by Macrophages of Mycobacterium bovis-Infected Goats and Supplemented with Dyhidroxyvitamin D3 in vivoAurora Martinez-Romero, Jose Luis Ortega-Sanchez, Jose Ramon Hernandez-Salgado et al.Problem statement: Tuberculosis (TB) remains one of the world's major health problems. To evaluate in vivo indices of cellular sensitization, antigen-induced Reactive Nitrogen Intermediates (RNI) responses by blood mononuclear cells from Mycobacterium bovis BCG-infected goats supplemented with 1, 25 dyhidroxyvitamin D3 [1, 25-(OH)2D3]. Approach: An experimental, longitudinal and comparative study was planned. Twelve animals of goat cattle 20-to 24-month-old sannen … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 1 · 31 Mar 2009 · 7,615 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAccumulation of Cholesterol Esters in ex vivo Lymphocytes from Scrapie-susceptible Sheep and in Scrapie-infected Mouse Neuroblastoma Cell LinesAlessandra Pani, Claudia Norfo, Claudia Abete et al.Our studies on the role of cholesterol homeostasis in the pathogenesis of scrapie in sheep, revealed abnormal accumulation of cholesterol esters in brains and in ex vivo skin fibroblasts from genetically scrapie-susceptible, as compared to sheep with resistant genotype. We now report that PBMCs isolated from scrapie-susceptible sheep, as well as mouse neuroblastoma cell lines persistently infected with two different … …American Journal of Infectious Diseases, Vol. 3, Issue 3 · 30 Sep 2007 · 6,955 accessesView PDFCite