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100 articles for “genome”
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Research ArticleOpen accessEvery word in the titleBayesian Exploration of Multilocus Interactions on the Genome-Wide ScaleIvan Kozyryev, Jing ZhangProblem statement: Recent technological and scientific advances propelled the field of Genome-Wide Association Study (GWAS), which promises to be instrumental in linking many common complex diseases to their genetic origin. While so far such large-scale surveys have been moderately successful in identifying disease related genetic variants, much of disease heritability is still not accounted for by the discovered loci. There … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 2 Jul 2012 · 7,401 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenome Sequence Analysis: A SurveyHassan Mathkour, Muneer AhmadProblem statement: Sequence analysis problems are NP hard and need optimal solutions. Interesting problems include duplicate sequence detection, sequence matching by relevance, sequence analysis using approximate comparison in general or using tools i.e., Matlab and multi-lingual sequence analysis. The usefulness of these operations is highlighted and future expectations are described. Approach: This study described the concepts, tools, methodologies, algorithms being … …Journal of Computer Science, Vol. 5, Issue 9 · 30 Sep 2009 · 6,830 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of the Cytogenetic Status, Genome Instability, and Adaptive Potential of the Kazakh Tobet DogOksana Cherednichenko, Anastassiya Pilyugina, Dinara Azizbekova et al.In recent years, interest in indigenous dog breeds has increased. The Tobet is a unique breed of Kazakh livestock guardian dogs adapted to nomadic pastoralism that developed over thousands of years across Central Asia and Turkestan. Currently, the Tobet breed faces critical endangerment. Its conservation and sustainable breeding require thorough analysis of hereditary characteristics, genome stability, and adaptive potential. In … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 4 · 19 Feb 2026 · 1,891 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleGenome-Wide Association Study of Single Nucleotide Polymorphisms with Milk Traits in Red Gorbatov CattleMarina Ivanovna Selionova, Grigorii Sergeyevich Shekhovtsev, Ivan Petrovich Prokhorov et al.In order to preserve the gene pool of the Red Gorbatov breed, it is necessary to use a set of genomic analysis tools that allows more efficient planning in obtaining individuals who meet the economic requirements of dairy farming. The aim of the work was to identify candidate genes associated with milk production traits in Red Gorbatov cattle using a … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 4 · 12 Oct 2024 · 4,736 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffectiveness of the Use of Genetic Markers of Meat Productivity in the Kazakh White-Headed Breed Identified Using Genome-Wide Association StudyIndira Beishova, Askar Nametov, Alzhan Shamshidin et al.The study aimed to determine the effectiveness of the use of genetic markers in cattle of the Kazakh white-headed breed identified using a genome-wide association study. The object of the study was the livestock of 790 Kazakh white-headed bulls bred in breeding farms of the Republic of Kazakhstan. The study adheres to rigorous ethical standards, with all procedures approved by … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 25 Jun 2024 · 5,023 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleHigh-Order Interactions in Rheumatoid Arthritis Detected by Bayesian Method using Genome-Wide Association Studies DataJing Zhang, Zheyang Wu, Chao Gao, Michael Q. ZhangProblem statement: In order to reveal the missing genetic component of Rheumatoid Arthritis (RA) susceptibility, we carried out a genome-wide high-order epistatic interaction study for RA. Approach: A powerful Bayesian strategy was applied to analyze the data of Genome-Wide Association Studies (GWAS) from the Welcome Trust Case Control Consortium (WTCCC), where 319 high-order interactions were found across the whole genome … …Current Research in Medicine, Vol. 3, Issue 1 · 30 Mar 2012 · 8,379 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Nested PCRs targeting the BI and SAG2 Genes For Detection of Toxoplasma gondii Genome in Aqueous Humor From HIV Positive Toxoplasma Retinochoroiditis Patients in a Tertiary Eye HospitalB. Mahalakshmi, K.L. Therese, R. Kirthika et al.Abstract: Problem statement: To evaluate nPCR targeting B1 gene (primer set 1) with 3 other nPCRs targeting B1 gene (primer set 2), 3' end of SAG2 and 5' end of SAG2 gene, for detection of Toxoplasma gondii (T. gondii) genome on AH from HIV positive TRC patients. Approach: DNA extracted from AH of 12 TRC patients and 12 controls (patients … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Dec 2010 · 6,886 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlecDNA Microarray Genome Image Processing Using Fixed Spot PositionBasim Alhadidi, Hussam Nawwaf Fakhouri, Omar S. AlMousaComplementary DNA (cDNA) microarray is one of the most recent and important technology for exploring the genome. cDNA microarray Image analysis aims to measure the intensity for each spot in the scanned image and this intensity represents the amount of a specific gene in the studied cell. This paper presents a new algorithm that achieves an automated way for applying … …American Journal of Applied Sciences, Vol. 3, Issue 2 · 28 Feb 2006 · 7,291 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparative Functional Analysis of the Basic Helix-Loop-Helix Proteins in the Clawed Frogs' Genomes With Common Essential Pathways and Enriched Gene Ontology TermsWuyi LiuThe international Gene Ontology (GO) and pathway databases were used to functionally analyze the clawed frogs' Basic Helix-Loop-Helix (bHLH) transcription factors of Xenopus tropicalis and Xenopus laevis in a updated genome-wide survey. There were 41 GO terms and one pathway significantly enriched for Xenopus tropicalis, whereas there were 45 GO terms and 3 pathways significantly enriched for Xenopus laevis. Among … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 1 · 28 Mar 2019 · 8,490 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMining, Isolation and Identification of Siderophore Synthesis Gene from Brevibacillus brevis GZDF3Miaomiao Sheng, Huake Jia, Xiaomai Tao et al.Objective of this paper is to excavate the siderophore synthesis gene from Brevibacillus brevis GZDF3 and verify its type and antibacterial effects. The method is using genome mining technology to analyze the siderophore synthesis genes and the phylogenetic tree of each synthesis gene was constructed separately. Iron free medium was utilized to induce the synthesis of siderophore and CAS liquid … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 28 Aug 2018 · 10,606 accessesView PDFCite