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72 articles for “drug resistant”
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Research ArticleOpen accessEvery word in the titleRelation between Macroscopic Binding Constant and the Anticancer Efficacy of the Bovine Serum Albumin-Quercetin Complex against Drug-Sensitive and Drug-Resistant CellsWinit Choiprasert, Chatchanok Loetchutinat, Nathupakorn Dechsupa, Samlee MankhetkornProblem statement: We have previously analyzed the interaction of BSA with flavonoids by using FRET. In this study, the role of BSA on increasing in solubility and on carrying the quercetin derivatives thus enhanced their anticancer efficacy against drug-sensitive and drug-resistant cells were conducted. Approach: The macroscopic (KD) and microscopic (kd) binding constant of the complexation and the cellular partition … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 1 · 27 May 2011 · 8,296 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,216 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdentification of Clonal Clusters of Klebsiella pneumoniae Isolates from Chennai by Extended Spectrum Beta Lactamase Genotyping and Antibiotic Resistance Phenotyping AnalysisC. Kamatchi, H. Magesh, Uma Sekhar, Rama VaidyanathanProblem statement: An increased resistance to antibiotics has been reported in Klebsiella pneumoniae, an opportunistic gram negative pathogen belonging to Entrobacteraceae due to the evolution and spread of plasmid encoded extended spectrum beta lactamases and other genes conferring cross-resistance to other antibiotics. This is of concern due to the increasing cost of antibiotic treatment and the spread of multidrug resistance … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,958 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Diversity of Isolated Mycobacterial Cultures in the Republic of Kazakhstan: Implications for Diagnostics and TreatmentAssiya Borsynbayeva, Kairat Turgenbayev, Gulzhauhar Sarsenova et al.The study of mycobacterial morphology in the Republic of Kazakhstan is relevant due to the increasing burden of tuberculosis and other mycobacterial diseases. The aim of this study was to comprehensively describe the morphological characteristics of different mycobacterial species identified in Kazakhstan, which will help to improve diagnostic methods and develop new approaches to treatment. Comparative and cross-cultural analyses were … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Dec 2025 · 2,205 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Evaluation of Synergistic Antibacterial Effects in Blended Essential Oil against Gram-Positive and Gram-Negative PathogensMin-Gi Kwon, Jae Kyung KimThe rising emergence of multidrug-resistant bacteria has heightened the search for novel antibiotic agents. Essential Oils (EOs) are complex combinations of volatile organic compounds generated by plants, with many exhibiting significant antimicrobial properties. This study evaluates the antibacterial movement of single and blended EOs against representative gram-positive bacteria Staphylococcus aureus and Methicillin-Resistant S. aureus (MRSA) and gram-negative bacteria Escherichia coli … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 7 Jul 2025 · 5,485 accessesView PDFCite
Research ArticleOpen accessIn the abstractVirtual Screening of CPP Conjugated Peptide as QcrB BCC Protein Inhibitors of Mycobacterium tuberculosis BacteriaMuhammad Ihsan Muttaqin, Manaman Huang, Usman Sumo Friend TambunanTuberculosis is a global leading cause of death, just below COVID-19 and ranked above HIV. This disease is caused by a pathogen called Mycobacterium tuberculosis, which spreads easily through the air and is known to remain latent in most people's bodies, about a quarter of the world's population. The current problems with TB also include two main concerns: The official … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 14 Mar 2024 · 5,523 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsolation and Characterization of Superior Symbiotic Bacterial Isolates from the Oenggae Sea with Potential as AntibacterialLukas Pardosi, Adelya Irawan Manalu, Charles Venirius LisnahanSponges are one of the marine biota that have a symbiotic relationship with bacteria which can produce secondary metabolites as antimicrobials. The main aim of this research was to isolate and identify bacteria that had potential as antibacterials against multi-drug resistant test bacteria. The sponsor samples used in this research were Stylissa massa, Salvador Dali, and Angelas sp. The methods … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 26 Mar 2024 · 5,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractColiforms Diversity and Antibiotic Resistance in Kazakhstan CheeseAnar Kuzeubayeva, Altay Ussenbayev, Ali Aydin et al.Coliform bacteria contaminate dairy products and pose public health concerns including food poisoning and toxemia. We aimed to determine the species diversity of coliforms and to evaluate the resistance to antibiotics of E. coli in various types of cheese sold by local producers in Kazakhstan. We collected 197 samples from different cheeses sold by producers in the Kostanay (n = … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 2 · 22 Feb 2024 · 6,000 accessesView PDFCite
Research ArticleOpen accessIn the abstractImplementation of Antimicrobial Stewardship Program During COVID-19 Era: Cost Effectiveness and Mortality RatesSafaa Alkhiami, Anass Qasem, Hussein Mohamed Hussein, Ali AbdallaThe growing spread of antimicrobial resistance is a major problem on a global level that has provoked several health and government organizations to call for action to counteract the problem. The frequent misuse of antibiotics is prevalent within hospital settings, especially during the COVID-19 era. The introduction of antibiotic stewardship initiatives has demonstrated the capability to decrease both unwarranted antibiotic … …American Journal of Infectious Diseases, Vol. 19, Issue 4 · 30 Jan 2024 · 6,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractResistance to Antibacterial Agents in Escherichia coli Isolated from Domestic Cats and Dogs in the Northern Region of the Republic of KazakhstanAnara Yeleussizova, Yuliya Aleshina, Anara Mendybayeva et al.The widespread use of antimicrobial agents for pets in veterinary practice has led to the emergence and spread of drug resistance not only in pathogenic but also in opportunistic bacteria. The study aims to evaluate the profile of resistance to antibacterial agents in Escherichia coli strains isolated from domestic cats and dogs, as well as to look into the determinants … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 3 · 2 Aug 2023 · 5,529 accessesView PDFCite