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Research ArticleOpen accessIn the abstractIoT-Integrated CNN Deep Learning for Automated Breast Cancer Detection and DiagnosisYamini Kalva, R. Ganesh Babu, Sindhu V. et al.Breast cancer continues to be a primary cause of death in women, requiring prompt and accurate diagnosis to enhance treatment results. Traditional diagnostic techniques depend on manual assessment, which leads to possible misclassification, significant inter-observer variability, and delays in decision-making. Current deep learning models, including CNNs, frequently experience feature loss, gradient declining and restricted adaptability to real-time data. To overcome … …Journal of Computer Science, Vol. 22, Issue 4 · 30 Mar 2026 · 1,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comprehensive Review of Medical Image Denoising: Techniques, Challenges, Applications and Future DirectionsMohit Sharma, Ayush Dogra, Anita Gupta et al.The concept of noise reduction in medical images plays a vital role in improving image quality and accuracy associated with diagnosis, and facilitating reliable automated analysis. This survey presents a structured overview of medical image denoising, beginning with foundational definitions and noise models for modalities such as MRI and CT. We critically evaluate persistent gaps, including the limited generalizability of … …Journal of Computer Science, Vol. 22, Issue 3 · 28 Mar 2026 · 1,861 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdvancing Stroke Lesion Segmentation With U-Net Variants: Classical, Transfer Learning, and MRI Sequence-Specific Customized ApproachesSonia Flora Panesar, Amit P. GanatraIschemic stroke, caused by restricted cerebral blood flow, is a leading cause of death and disability worldwide. Accurate segmentation of stroke lesions in MRI is essential for timely diagnosis but remains labor-intensive when done manually. This study presents a comparative evaluation of three U-Net variants for automated ischemic stroke lesion segmentation using the ISLES 2022 dataset: (1) Classical U-Net with … …Journal of Computer Science, Vol. 22, Issue 2 · 27 Feb 2026 · 1,797 accessesView PDFCite
Literature ReviewOpen accessIn the abstractPotential Therapies for Mitochondrial Diseases Caused by mtDNA MutationsAnastasia V. Poznyak, Nikolay A. Orekhov, Dmitry Felixovich Beloyartsev et al.Mitochondrial diseases, caused by mutations in mitochondrial DNA (mtDNA), present significant genetic and clinical complexities that challenge accurate diagnosis and treatment. This review examines the critical molecular mechanisms underlying these disorders, particularly the role of heteroplasmy, where mixtures of mutated and normal mtDNA influence disease severity, and the nuclear-mitochondrial DNA interactions that compound diagnostic and therapeutic challenges. The threshold effect, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,750 accessesView PDFCite
Research ArticleOpen accessIn the abstractCuckoo Search Optimized Random Forest for Breast Cancer PrognosisPrasad S. Sase, Debabrata Swain, Shailesh KumarBreast cancer remains a major global health concern due to its high mortality rate, particularly when diagnosis occurs at an advanced stage. Accurate and early differentiation between benign and malignant tumors is therefore critical for improving patient outcomes. Conventional diagnostic practices largely depend on manual assessment and clinical expertise, which may lead to subjective variability in decision-making. To overcome this … …Journal of Computer Science, Vol. 22, Issue 1 · 31 Jan 2026 · 2,107 accessesView PDFCite
Case ReportOpen accessIn the abstractA Case Report of Severe Malaria Due to Plasmodium falciparum Malaria Complicated by Symmetrical Peripheral Gangrene (SPG) at the Matlaboul Fawzaini National Hospital Center, Touba, SenegalJules Yindoni Zande, Ndeye Fatou Ngom et al.Malaria remains a major public health problem worldwide, particularly in Africa. Symmetrical Peripheral Gangrene (SPG) is a distal ischemic lesion affecting at least two extremities in the absence of proximal arterial obstruction and vasculitis. It is a rare and severe clinical entity. Its association with malaria is rare, with approximately 27 cases reported worldwide, mostly in Asia. A 15-year-old male … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 22 Jan 2026 · 2,811 accessesView PDFCite
Research ArticleOpen accessIn the abstractPerformance Analysis of Modified Enhancement Method for Dental Images - Towards the Effective Detection of Dental DisordersKrishnaveni R, Sudarmani RDental health maintenance is essential for overall physiological well-being, and X-ray imaging remains a fundamental diagnostic tool for comprehensive dental examination. While direct clinical observation by dentists is primary, computer-aided diagnostic tools serve as valuable secondary readers, enhancing diagnostic accuracy and efficiency. This study proposes and evaluates the Gaussian CLAHE Enhancement (GCE) method, which combines Gaussian filtering (GF) with Contrast … …Journal of Computer Science, Vol. 21, Issue 11 · 18 Dec 2025 · 1,723 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptiCNN: Local thresholding segmentation and CNN with SVM Approach for Diabetic Retinopathy Detection and Classification of Fundus ImagesAnju Mishra, Mrinal Pandey, Laxman SinghDiabetic Retinopathy (DR) is a progressive eye disease that can lead to vision loss and blindness if left untreated. Ophthalmologists diagnose DR using medical imaging modalities such as fundus photography and optical coherence tomography (OCT); however, manual interpretation of these images is time-consuming and subject to inter-observer variability. While DR is irreversible, vision loss can be prevented through early detection … …Journal of Computer Science, Vol. 21, Issue 10 · 15 Dec 2025 · 2,162 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis of Binary Patterns Pyramid and Gabor Filters for Machine Learning-Based Nail Disease DetectionJagadeeswari Boopalan, Maruthu Perumal SabtharishiNail diseases, including Onychomycosis and Psoriasis, are common conditions that pose diagnostic challenges due to subtle clinical presentations and reliance on invasive methods. This study investigates the effectiveness of Binary Patterns Pyramid Filter (BPPF) and Gabor Filter (GF) as feature extraction techniques for machine learning-based nail disease detection, addressing three categories: Healthy, Onychomycosis, and Psoriasis. Using a dataset of 1,466 … …Journal of Computer Science, Vol. 21, Issue 8 · 2 Oct 2025 · 2,183 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis on Prediction of Chronic KidneyDisease by various Machine Learning ModelsNikhil Verma, Tripti Sharma, Bobbinpreet Kaur, Ayush DograChronic Kidney Disease (CKD) is a prevalent global healthconcern, which is affecting a number of people in the whole world. Earlydetection & precise checking of CKD are really important for essentialsupervision & intervention to prevent disease progression and associatedcomplications. Machine learning (ML) models have emerged as favourabletools for CKD detection due to their ability to analyse complex data patternsand provide … …Journal of Computer Science, Vol. 21, Issue 6 · 24 May 2025 · 5,947 accessesView PDFCite