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115 articles for “biological activity”
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Research ArticleOpen accessIn the keywordsStudy of Chemical Composition of Extract from Beta Vulgaris Seeds and its Cytotoxic ActivityAiman Konkabayeva, Margarita Ishmuratova, Gulmira Tykezhanova et al.Nowadays, a variety of plants is being investigated with the aim of developing new medicines with improved properties and expanding the range of efficient and safe preparations. Modern studies of representatives of the family Amaranthaceae (Beta vulgaris) have revealed medicinal properties in plants that were used previously only as food. Many medicinal properties are due to the presence of betalains … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 27 May 2021 · 6,220 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTheoretically Predicted Descriptors Based Quantitative Structure Activity Relationship Study of the Activity of Acridines Against B-16 MelanomaBahjat A. Saeed, Rita S. Elias, Sadiq M-H. Ismael, Kawkab A. HussainProblem statement: The probability of success and reducing time and coast in drug discovery process could be increased on the basis of QSAR techniques. The study involves the QSAR investigation of 20 bioactive acridines that have activity against Approach: Molecular descriptors, total energy, van der Waals volume, molecular volume, HOMO energy, HOMO-LUMO energy gap, polarizability, refractivity, bond angle of C8-N9-C2 … …American Journal of Applied Sciences, Vol. 8, Issue 8 · 18 Jul 2011 · 7,689 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSynthesis, Characterization and Biological Activities of Organotin (IV) Methylcyclohexyldithiocarbamate CompoundsNormah Awang, Ibrahim Baba, Bohari M. Yamin et al.Problem statement: The growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. Approach: Novel organotin compounds with the molecular formula RmSn[S2CN(CH3)(C6H11)]4-m (where m = 2, R = CH3, C2H5; m … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 9,210 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSynthesis and Characterization of Organotin(IV) Complexes Derived of 3-(Dimethylamino)benzoic Acid: Cytotoxic Assay on Human Liver Carcinoma Cells (HepG2)Yip-Foo Win, Siang-Guan Teoh, Tengku-Sifzizul Tengku-Muhammad et al.Problem statement: Many studies have been carried out on organotin(IV) complexes derivative of carboxylate anions. However, the synthesis and characterization as well as the cytotoxic assay of organotin(IV) carboxylate derived of 3-(dimethylamino)benzoic acid have not been studied. Approach: Organotin(IV) carboxylate complexes derivative of 3-(dimethylamino)benzoic acid, 3-[N(CH3)2]C6H4COOH have been successfully synthesized. Two types of diorganotin(IV) complexes, [{3-[N(CH3)2]C6H4COO(R)2Sn}2O]2 dimer (R = methyl … …American Journal of Applied Sciences, Vol. 7, Issue 3 · 31 Mar 2010 · 8,310 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBiocontrol of Winter Wheat Root Rot by Rhizosphere Microorganisms in KazakhstanNurlan Kuldybayev, Amankeldy Sadanov, Aigerim Qairatova et al.Root rot remains one of the most significant diseases of winter wheat (Triticum aestivum L.) in Kazakhstan, resulting in substantial yield losses. This study aimed to isolate and identify rhizosphere microorganisms associated with winter wheat and evaluate their antagonistic activity against root rot pathogens in the Almaty region of Kazakhstan. In total, seven bacterial and fungal isolates, belonging to the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 25 Aug 2026 · 933 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSeed Treatment-Based Biocontrol of Tomato Damping off Using Plant Essential Oil and Green Silver NanoparticlesLaila Reklaoui, Zine El Abidine Bzazou Elouazzani, El Touhami Tayebi Ouazzani et al.The fungal pathogen Rhizoctonia solani is a major causal agent of damping-off in tomato plants, leading to severe yield losses worldwide. Conventional fungicides, while effective, raise concerns regarding environmental safety and human health, highlighting the urgent need for sustainable alternatives. In this study, we report for the first time the use of Origanum compactum essential oil to biosynthesize silver nanoparticles … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 2 Jun 2026 · 1,298 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAnticancer Activities of Some New Synthesized Thiazolo[3,2-a]Pyrido[4,3-d]Pyrimidine DerivativesAshraf M. Mohamed, Abdel-Galil E. Amr, Musaed A. Alsharari et al.Problem statement: This study describes the synthesis and anticancer activities of a new series of thiazolo[3,2-a]pyrimidines derivatives (2-7) using 3,5-bisarylmethylene-1-methyl-4- piperidone and 4-aryl-8-arylmethelene-6-methylpyrido[4,3-d]pyrimidine-2(1H)thiones as a starting materials. Approach: The antitumor activities of the newly synthesized compounds 4-7 were evaluated utilizing 60 different human tumor cell lines, representing leukemia, melanoma, lung, colon, brain, ovary, breast and prostate as well as kidney. … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 2 · 23 Aug 2011 · 10,087 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Organic Ameliorants on Grey Soil FertilityAsanbay Tagaev, Amandyk Kostakov, Sabir MakhmadzhanovThe study aimed to assess the effectiveness of organic-biological ameliorants for restoring the fertility of light grey soils in the Turkestan region of Kazakhstan, which are characterised by low humus content (0.8-1.1%) and high alkalinity (pH 7.9-8.3). The field experiment was conducted on an area of 2304 m2 using four treatment options: control (variant 1 only mineral fertilisers) and three … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 15 Sep 2026 · 693 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntegrated Monitoring of Endocrine-Disrupting Chemicals: Analytical Chemistry and Biological Assessment ApproachesChangjin Li, Jing Huo, Zijun Dou et al.Endocrine-Disrupting Chemicals (EDCs) in aquatic environments pose significant threats to ecosystems and human health. These compounds interfere with hormonal regulation at low concentrations and have non-monotonic dose-response relationships, posing challenges to conventional risk assessment. This review systematically compares current EDC monitoring methods, including instrumental chemical analysis and receptor-based biological detection systems, to evaluate sensitivity thresholds, sample throughput, and mechanistic selectivity … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 3 Jul 2026 · 1,081 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Foliar Bio-Based Fertilization on Spring Wheat (Triticum Aestivum L.) in Reconciling Productivity and Alleviation of Environmental Concerns Under Semi-Arid ConditionsGani Stybayev, Raushan Ramazanova, Kelvin Harrison Diri et al.A two-year randomized field trial was conducted to evaluate the effects of foliar bio-based fertilization on the growth, productivity, grain quality, and soil health of spring wheat (Triticum aestivum L.) under semi-arid conditions in Northern Kazakhstan. Four treatments were compared: T0 (100 kg Ammophos, mineral fertilizer control), T1 (50 kg N14P23 + biotreatment), T2 (25 kg N14P23 + biotreatment), and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,526 accessesView PDFCite