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19 articles for “bilirubin”
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Research ArticleOpen accessIn the abstractGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,499 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Prophylactic and Therapeutic Effects of Silymarin on Diazepam-Induced Hepatotoxicity in CatsBahman Mosallanejad, Reza Avizeh, Hossien NajafzadehProblem statement: Diazepam is commonly administered for seizure control and appetite stimulant in cats. Cats may develop acute fatal hepatic necrosis after receiving oral diazepam for several days. The aim of this study was to detect the protective action of silymarin on diazepam-induced hepatotoxicity in cats. Approach: About 25 healthy cats were randomly allotted to five equal groups. Animals in … …American Journal of Applied Sciences, Vol. 8, Issue 9 · 29 Jul 2011 · 7,430 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute and Sub-Acute Toxicological Assessment of Aqueous Leaf Extract of Bryophyllum Pinnatum (Lam.) in Sprague-Dawley RatsRaymond Iduojemu Ozolua, Sylvester Eshiotseme Idogun, Glory Eshiagiamhe TafamelProblem statement: The aqueous leaf extract of Bryophyllum pinnatum has been reported to possess antihypertensive, antiinflammatory, antimicrobial, antidiabetic and antiulcer properties among others. Being readily available and easy to cultivate, the use of the plant in herbal medicine has been on the increase. Although there are few toxicological reports on the extract, these have not been sufficiently extensive. We therefore … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 3 · 30 Sep 2010 · 9,385 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatotoxicity Due to Histamine Trifluoro-Methyl Toluidide, Amthamine, R-(-)-α-Methyl Histamine and Clobenpropit (H1R-H4R-Agonists, Respectively) in Rabbit Experimental ModelTrivendra Tripathi, Aijaz Ahmed Khan, Mohammad Shahid et al.Problem statement: Since in vivo studies looking for toxicological impact of histamine receptors-agonists in experimental models are fragmentary, the present study was designed to delineate the histopathological and biochemical changes in livers of rabbits treated with histamine receptors (H1R-H4R)-agonists. Approach: The cohort comprised of six groups (Group I control and Group II-VI treated) containing five rabbits each. Control-group received vehicle … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 8,905 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical Changes in Wistar Rats on Oral Doses of Mistletoe (Loranthus micranthus)D. O. Edem, I. F. UsohProblem statement: To evaluate the effects of the water extract of the leaves of mistletoe (Loranthus micranthus) (traditionally used antidiabetic and antihypertensive) in male albino Wistar rats. Approach: The animals were divided into 4 groups (n = 6). Water extract of L. micranthus leaves was administered in graded doses of 0, 275, 551 and 827 mg kg-1 body weight (wt) … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 8,547 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects against Aluminum Chloride-Induced Toxicity in the Liver and Kidney of White Albino RatsFahaid Al-HashemProblem statement: Aluminum chloride (AlCl3) is commonly used in daily life but it can be potentially toxic. Therefore, the present study was carried out to investigate the protective effects of camel’s milk against aluminum-induced biochemical alterations and oxidative stress in the liver and kidney of white albino rats. Approach: White albino male rats (230-250 g) were divided into three groups … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 10,376 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatoprotective Activity of Aqueous Ethanolic Extract of Chamomile capitula in Paracetamol Intoxicated Albino RatsAjay k. Gupta, Neelam MisraHepatoprotective activity of aqueous ethanolic extract of Chamomile recutita capitula against paracetamol induced hepatic damage in albino rats was observed. In the present study the effect of aqueous ethanolic extract of Chamomile recutita capitula on blood and liver glutathione, Na+ K+- ATPase activity, serum marker enzymes, serum bilirubin, glycogen and thiobarbutiric acid reactive substances against paracetamol induced damage in rats … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 18,953 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Air Pollution and Smoking on Cadmium Concentration in Human Blood and Correlation with Biochemical ParametersL. Zeneli, H. Paçarizi, N. M. Daci et al.Problem statement: The study described the research of the effects that the environment pollution and smoking have in cadmium concentration in human blood, as well as in the correlation between cadmium and the biochemical parameters. Approach: In a comparative study of cadmium concentration in blood of human population of two different environments in Kosovo, one nearby Kosovo Thermo Power Plants … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 2 · 30 Jun 2009 · 28,204 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of pollution on lead and cadmium concentration and correlation with biochemical parameters in blood of human population nearby Kosovo thermo power plantsEugene Oks, N.M. Daci, M.N. Daci-Ajvazi, H. PaçariziThis study describes an investigation of lead and cadmium pollution of Kosovo environment as a result of outflow from the coal processing industry. In a comparative study of lead and cadmium concentration in blood of human population of two different environments in Kosovo, one nearby Kosovo Thermo Power Plants, (Obiliq) a highly polluted environment and the other that is considered … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,196 accessesView PDFCite