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Research ArticleOpen accessIn the abstractNovel Production of Two New Nonpolyenic Antifungal Macrolide Derivatives by Streptomyces Z26 Isolated from Moroccan Rhizospheric SoilAhmed Nafis, Brahim Oubaha, Najoua Elhidar et al.The aim of our study was to screen Moroccan actinomycete isolates able to produce nonpolyenic antifungal metabolites in order to contribute to limiting the problem of fungal infections emergence in particular mycotic diseases and to discover known antifungal families, especially nonpolyenic drugs. 480 isolates were tested against 5clinically pathogenic Candida species. Several methods have been used to study the polyenic … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 8 Mar 2018 · 8,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractCastor Oil Based Epoxy/Clay Nanocomposite for Advanced ApplicationsAditi Saikia, Niranjan KarakBio-based hyperbranched and linear epoxy resins were synthesized from monoglyceride of Ricinus communis oil. The nanocomposites of these hyperbranched and linear epoxies with 1, 2 and 3 wt% of OMMT were also fabricated. The structures of the resins and their nanocomposites were analyzed by FTIR, NMR, XRD, SEM and TEM. The studies of performance characteristics of poly(amido amine) cured thermosetting … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 1 · 29 Dec 2015 · 8,359 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis and Biological Evaluation of 6-Hydroxy-4-Methyl-5,7-(Bis-p-ChlorophenylAzo) CoumarinDalal M. Ibrahim, Juliana Jumal, Farah Wahida Harun6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarinhas been synthesized and characterizedby CHN elemental analysis, FTIR, 1H-NMR-spectroscopy andmass-spectral data. Cytotoxic screening by MTT assay was carried out on the compoundagainst breast cancer cells. The overall results from preliminary screeningprogram revealed that the cell proliferation was highly inhibited by 6-hydroxy-4-methyl-5,7-(bis-p-chlorophenylazo)coumarin with the value of 2.81%, at concentration of 30 µg mL-1 comparedwith the untreated control cells and also … …American Journal of Applied Sciences, Vol. 13, Issue 1 · 21 Dec 2015 · 7,670 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Model for Resolving Flow Parameters for MRI-Neuroimaging ApplicationMoses E. Emetere, M.L. AkinyemiThe functionality of recent neuroimaging using the MRI machine has generated errors which are peculiar to all kinds of MRI processes. Though hardwares are used to complement the MRI process, the problems are not completely solved due to its fundamental errors. The fundamental error is in the exclusion of molecular interaction in the ab-initio Bloch NMR. A new mathematical concept … …American Journal of Applied Sciences, Vol. 12, Issue 9 · 29 Sep 2015 · 6,724 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis of Well-Defined Vinyl End-Functional Polystyrene Using Multifunctional Initiator by Atom Transfer Radical PolymerizationSamiul Islam Chowdhury, Roushown Ali, Tariqul HasanAtom Transfer Radical Polymerization (ATRP) has proven to be a powerful technique to obtain polymers with narrow polydispersities and controlled molecular weight. It also offers control over chain-ends. N-allyl-2-bromopropinamide (ABPN) was synthesized by one step reaction which involved on amidification of 2-bromo-propionyl bromide with allyl amine. 1H NMR has confirmed the structure of the ABPN. The well-defined polystyrene was synthesized … …American Journal of Applied Sciences, Vol. 12, Issue 8 · 13 Sep 2015 · 7,048 accessesView PDFCite
Research ArticleOpen accessIn the abstractTotal Synthesis of Endangered Frog Alkaloid ’Epibatidine’, A Potent Analgesic of the FutureN.R. Dhatrak, M.G. Kulkarni’Epibatidine’ is a nicotinic alkaloid’, was first discovered in the skin of neotropical poisonous frog, ’Epipedobates tricolor’ found in Ecuador. John Daly in 1974 first isolated a trace quantity of this alkaloid by scarifying several frogs. With the evolution of NMR techniques the structure of this alkaloid was reported in 1992. An year after, Nobel Laureate Prof. E.J. Corey, devised … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 17,112 accessesView PDFCite
Research ArticleOpen accessIn the abstractA HIGH B1 FIELD HOMOGENEITY GENERATION USING FREE ELEMENT ELLIPTICAL FOUR-COIL SYSTEMSidi M. Ahmed Ghaly, Sulaiman S. Al-SowayanDesign and testing of a prototype probe with high B1 magnetic field homogeneity that can be used for MRI is presented. It consists of four coaxial separately tuned rings of wire in a symmetric arrangement on an ellipsoidal surface. Compared to Helmholtz pair, which presents 2nd-order homogeneity, an improvement in field homogeneity is achieved, while preserving the simplicity of implementation. … …American Journal of Applied Sciences, Vol. 11, Issue 4 · 28 Jan 2014 · 7,019 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification and Mode of Action of Antibacterial Components from Melastoma malabathricum Linn LeavesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to assess the antibacterial activity of the methanol extract of Melastoma Malabathricum Leaves (MMML), active fraction of M. Malabathricum Leaves (ML5) and isolated kaempferol-3-O-(2",6"-di-O-p-trans-coumaroyl)-β-glucopyranoside (Kf) and to describe the preliminary mode of action against Gram-positive and Gram-negative bacteria. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) to afford M. malabathricum Leaves fractions (ML1-ML6) of … …American Journal of Infectious Diseases, Vol. 9, Issue 2 · 18 Jun 2013 · 12,621 accessesView PDFCite
Research ArticleOpen accessIn the abstract(+)-Syringaresinol Lignan from New Species Magnolia ThailandicaWisit Monthong, Siripit Pitchuanchom, Narong Nuntasaen, Wilart PompimonProblem statement: Magnolia, an ancient genus, is a large genus of about 210 flowering plant species in the subfamily Magnolioideae of the family Magnoliaceae. Having evolved before bees appeared, the flowers developed to encourage pollination by beetles. Members of this family are rich in a wide variety of biological active compounds including lignans. Magnolia thailandica, a new species for Thailand … …American Journal of Applied Sciences, Vol. 8, Issue 12 · 11 Oct 2011 · 9,283 accessesView PDFCite