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28 articles for “Pro-Inflammatory Cytokine”

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Research ArticleOpen accessIn the abstractHumoral and Cellular Effects of Stress-An Extensive Model SystemMazal Shimon-Hophy, Ramy R. AvtalionThe influence of stress on the immune system of the common carp (Cyprinus carpio) was studied by measuring leukocytes levels using flow cytometry and mRNA immune components by real time qPCR. Acute and chronic oxidative stresses were generated by different regimes of exposure of carp to environmental air. In acute stress, induced by single air exposure, the pro-inflammatory cytokines (IL1β, … …American Journal of Immunology, Vol. 13, Issue 2 · 18 Apr 2017 · 6,728 accessesView PDFCite
Review ArticleOpen accessIn the abstractPromising Effects of Beta-Glucans on Metabolism and on the Immune Responses: Review ArticleViviam de Oliveira Silva, Natália Oliveira de Moura, Larissa Jahnel Rodrigues de Oliveira et al.A public health issue, Diabetes mellitus, affects millions of people around the globe. Ingestion of foods with a low glycemic index - fiber-rich meals-such as beta-glucans, is increasing as an important alternative for diabetes control. These compounds act reducing parameters such as blood glucose, cholesterol and triglycerides, by decreasing the absorption of glucose and lipids by enterocytes and eventually promote … …American Journal of Immunology, Vol. 13, Issue 1 · 29 Mar 2017 · 12,689 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of a Mushroom (Coriolus versicolor) Based Probiotic on Goat HealthKingsley Ekwemalor, Emmanuel Asiamah, Sarah Adjei-Fremah, Mulumebet WorkuMaintenance of an adequate immune response is essential to goat health. CorPet biomass is a mushroom (Coriolus versicolor) based probiotic used as an immune-stimulant in man, horses and small animals. Fifteen BoerXSpanish goats were used in a crossover design to evaluate the effect of a commercial mushroom based probiotic across two periods on resilience of goats to gastrointestinal parasites in … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 4 Oct 2016 · 7,925 accessesView PDFCite
Research ArticleOpen accessIn the abstractDouble Application of Translocator Protein Ligands and RAW Cells Inflammatory MilieuMaria Staykova, Filomena Mattner, David Linares, Andrew KatsifisLigands targeting the translocator protein exhibit a variety of anti-inflammatory and neuroprotective properties. A double application of eight translocator protein ligands to activated murine macrophage-like cells changed to a different extent the levels of secreted reactive nitrogen intermediates, pro- and anti-inflammatory cytokines. To our knowledge this is the first report suggesting that multiple applications of different translocator protein ligands may … …American Journal of Immunology, Vol. 12, Issue 3 · 28 Aug 2016 · 6,946 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Duality of AIM2 Inflammasome: A Focus on its Role in Autoimmunity and Skin DiseasesMiriam CanaveseUnderstanding the inflammasome biology is one of the most exciting challenges in immuno-pharmacology. The role of the inflammasomes has been recognized in the host defense mechanism against invading pathogens and in the development of several conditions, such as cancer, auto-inflammatory, autoimmune, metabolic and neurodegenerative disorders. DNA recognition by the cells is a crucial immunological step leading to the initiation of … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 1 · 23 Apr 2016 · 7,376 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of Cytokines and Transcription Factors in Periodontitis: A Review of Cellular and Molecular MechanismsAnne Carolina Eleutério Leite, Valéria Martins de Araújo Carneiro, Júlia Faria Nunes et al.Periodontal Diseases (PD) are characterized by pathological manifestation of host immune response to bacterial infection at the tooth/gingival interface. Evidences points periodontitis as a risk factor for pathological systemic conditions, such as, cardiovascular diseases and diabetes. The identification of host factors that determine their susceptibility to immune subversion can provide useful information in the pathogenesis of periodontitis. Protective acute inflammatory … …American Journal of Immunology, Vol. 11, Issue 4 · 9 Dec 2015 · 7,809 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Properties of Kaurenoic Acid on Macrophages of BALB/c in VitroJuliana Aparecida Macri, Suelen Santos da Silva, Milena Menegazzo Miranda et al.Kaurenoic acid has been displaying anti-inflammatory effect described in different models. However, the per se immunomodulatory effects of kaurenoic acid remain to be investigated. Thus, the immunomodulatory and antioxidant effects of kaurenoic acid were investigated in vitro on peritoneal macrophages from BALB/c mice. Kaurenoic acid induced per se the production of pro-inflammatory cytokines such as TNFα, IL-1β and IFN-γ while … …American Journal of Immunology, Vol. 10, Issue 4 · 16 Feb 2015 · 7,885 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibition of Interleukin-6 Expression by Curcumin in Rat Vascular Smooth Muscle Explants In VitroYanti, Stephanie, Yuliani et al.In atherosclerotic plaques, infectious agents from microbes may release Lipopolysaccharide (LPS) and heat shock proteins that can stimulate the production of mediators, i.e., pro-inflammatory cytokines, by vascular endothelial cells and Smooth Muscle Cells (SMCs). The elevated level of Interleukin-6 (IL-6) is strongly associated with the development of atherosclerosis. Here, we investigated whether curcumin isolated from the rhizome of Curcuma longa … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 15 Dec 2014 · 6,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractMORINGA TEA BLOCKS ACUTE LUNG INFLAMMATION INDUCED BY SWINE CONFINEMENT DUST THROUGH A MECHANISM INVOLVING TNF-α EXPRESSION, C-JUN N-TERMINAL KINASE ACTIVATION AND NEUTROPHIL REGULATIONMykea Mcknight, Jabria Allen, Jenora T. Waterman et al.Plant based products represent a promising alternative to conventional treatments for inflammation. Moringa oleifera Lam is a tree rich in proteins, vitamins, minerals and a variety of phytochemcals with health benefits. Among the reported health benefits are antioxidant and anti-inflammatory properties. The purpose of this study was to investigate whether tea brewed from dried Moringa leaves would abrogate inflammation in … …American Journal of Immunology, Vol. 10, Issue 2 · 8 May 2014 · 11,603 accessesView PDFCite