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31 results for “Mycobacterium tuberculosis”
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Research ArticleOpen accessIn the keywordsDesign, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular AgentsMehul M. Patel, Mahesh T. ChhabriyaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Although many active antitubercular agents have since been developed, drug resistance will continue to be a problem. Therefore, there is a clear … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 3 Nov 2011 · 7,430 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA 30 Year Old Man with Fever and Indolent Soft Tissue MassesWissam Zaeeter, Ashwin Jathavedam, Rosalyn StahlAbstract: Problem statement: Multifocal Skeletal Tuberculosis (MSTB) is a rare presentation of skeletal tuberculosis. The indolent nature of this condition often leads to delayed or missed diagnosis, sometimes with devastating consequences for the patient. In order to provide meaningful clinical information and to highlight pitfalls in diagnosis of MFST, we present a case of MSTB. A review of this condition … …American Journal of Infectious Diseases, Vol. 6, Issue 3 · 30 Sep 2010 · 7,713 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffect of Antioxidant Vitamins C and E Supplementation on its Plasma Levels and on Lipid Profile in Pulmonary Tuberculosis PatientsM. Madhavi, P. Samudram, A. Hemanth Kumar, Lalitha VictorProblem statement: Patients with active pulmonary Tuberculosis (TB) are malnourished as indicated by reductions in lean mass, anthropometric indices and micronutrient status. Supplementation with vitamins may prove to be beneficial. Limited information is available on the supplementation of vitamin C and E in pulmonary TB patients. Hence, the present study was undertaken to address the question whether any benefit could … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,684 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAnalysis of Interferon-Gamma Release Assay Results for Latent Tuberculosis Infection Diagnosis at a Referral Clinical Laboratory in South KoreaTae Soung Kim, Ga Yeon Kim, Young Ki Lee, Jae Kyung KimThe world health organization states that individuals with Latent Tuberculosis Infection (LTBI) are infected with Tuberculosis (TB) bacteria but do not show symptoms of active disease. However, they are at possibility of developing vigorous TB and potentially transmitting the illness to others. In 2018, South Korea reported a 14.8% positivity rate in LTBI screening, with higher rates observed among older … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 25 Oct 2023 · 6,033 accessesView PDFCite
Review ArticleOpen accessIn the keywordsScope and Perspectives of New TB Drugs and VaccinesJaishree Meena, Laxman S. MeenaTuberculosis remains a major threatening infectious disease claiming millions of lives every year; hence increasing the global burden of TB disease. Co-infection with human immuno-deficiency virus and emergence of multi-drug resistant tuberculosis, extremely drug resistant tuberculosis and totally drug resistant tuberculosis enhances deadly effect of tuberculosis. To eliminate TB disease from human population several partnerships are working together like Stop … …American Journal of Infectious Diseases, Vol. 11, Issue 3 · 10 Sep 2015 · 7,943 accessesView PDFCite
Research ArticleOpen accessIn the abstractRisk Factors for Bovine Tuberculosis Transmission in Burkina Faso’s Cattle HerdsArouna Zoungrana, Pingdwende Albert Patrick Vokouma, Badjibassa Akounda et al.Bovine tuberculosis is a zoonotic disease, primarily caused by Mycobacterium bovis, that poses a serious threat to both human and animal health. Understanding the risk factors that contribute to its spread is critical for developing effective prevention and control strategies. This cross-sectional study investigated risk factors associated with bovine tuberculosis in cattle herds in Burkina Faso. A structured survey questionnaire … …American Journal of Animal and Veterinary Sciences, Vol. 21, Issue 1 · 11 Apr 2026 · 1,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Diversity of Isolated Mycobacterial Cultures in the Republic of Kazakhstan: Implications for Diagnostics and TreatmentAssiya Borsynbayeva, Kairat Turgenbayev, Gulzhauhar Sarsenova et al.The study of mycobacterial morphology in the Republic of Kazakhstan is relevant due to the increasing burden of tuberculosis and other mycobacterial diseases. The aim of this study was to comprehensively describe the morphological characteristics of different mycobacterial species identified in Kazakhstan, which will help to improve diagnostic methods and develop new approaches to treatment. Comparative and cross-cultural analyses were … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Dec 2025 · 2,203 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe European Wild Boar (Sus scrofa) as a Reservoir of Tuberculosis: Ecological Drivers and Management ImplicationsGiovanna Liguori, Renato Lombardi, Fabio Castagna et al.Bovine tuberculosis (bTB), an infectious disease primarily caused by Mycobacterium bovis and other members of the Mycobacterium tuberculosis complex, represents a significant challenge to both animal and public health. Despite successful control programs in numerous regions, the presence of wildlife reservoirs, notably wild boar (Sus scrofa), impedes complete eradication and sustains disease propagation. bTB prevalence varies across Europe, with higher … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 16 Nov 2025 · 2,621 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional CultureHo Keun Choi, Ga Yeon Kim, Tae Soung Kim, Jae Kyung KimDefining the molecular mechanisms underlying the dormant state of Mycobacterium tuberculosis (MTB) is essential for developing more effective treatments for tuberculosis (TB) infection. We investigated the positivity and resistance rates of TB tests on 6,174 samples referred to a single hospital. Of these, 342 cases (5.5%) were confirmed as positive by acid-fast bacilli staining, 243 cases (71.1%) were detected as … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 5 Dec 2024 · 4,206 accessesView PDFCite
Review ArticleOpen accessIn the abstractBioprospection of Endophytic Bacteria Isolated from Mangrove Ecosystems and their Potential Biotechnological ApplicationsAlfian Mubaraq, Mariani Sembiring et al.The unique mangrove ecosystem hosts a variety of microorganism activities, including the crucial role of endophytic bacteria. Microorganisms found in mangrove forests play an important role in maintaining the biosphere by uniting various living beings and can be vital for future biotechnological applications. The use of microorganisms in the field of biotechnology is prevalent for producing antimicrobials against pathogenic bacteria … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 Aug 2024 · 4,996 accessesView PDFCite