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65 articles for “Mechanism of Action”
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Short CommunicationsOpen accessIn the abstractCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Approach to a Self-Organizing Federation of MQTT BrokersNicolas Kolling Ribas, Marco Aurélio SpohnIn the Publish/Subscribe (PS) communication paradigm clients producing content (i.e., publishers) send it to a broker, which relays the content to consumers (i.e., subscribers). Communication can happen asynchronously, leaving all the hurdles to the server/broker. MQ Telemetry Transport (MQTT) is the most used P/S protocol in designing IoT applications. The usual MQTT scenario comprises a single broker, making it a … …Journal of Computer Science, Vol. 18, Issue 7 · 29 Jul 2022 · 6,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractCheating Detection in Examinations Using Improved YOLOv8 with Attention MechanismYan Zuo, Soo See Chai, Kok Luong GohExaminations are among the most widely used and effective methods for assessing knowledge mastery, both domestically and internationally, and are extensively used in various talent-selection processes. Currently, offline exam venues usually rely on on-site manual invigilation combined with exam-monitoring videos to further strengthen invigilation efforts. However, this invigilation method not only utilizes large amounts of human and material costs but … …Journal of Computer Science, Vol. 20, Issue 12 · 6 Nov 2024 · 6,253 accessesView PDFCite
Research ArticleOpen accessIn the abstractThermodynamic Inference of the Antioxidant Process of Malic Acid and Its Structural AnalogsHan Wu, Wenhao Dong et al.Two structural analogs of Malic Acid (MA), 2-isopropylmalic Acid (2-IPMA), and 3-isopropylmalic Acid (3-IPMA) were recently identified and separated from wine. Although they have been shown to have antioxidant activity, the mechanism of their actions is still unclear. Antioxidant activities of 2-IPMA and MA were tested through DPPH, ABTS, and PTIO methods and the antioxidant-related thermodynamic properties were evaluated using … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 30 Oct 2024 · 4,824 accessesView PDFCite
Research ArticleOpen accessIn the abstractParacetamol: A Focus on DogsCharbel Fadel, Irene Sartini, Mario GiorgiParacetamol (APAP) is an aniline analgesic, antipyretic and non-narcotic. It is an essential drug, widely used in human medicine. In veterinary medicine it has an extra label use in many countries. It is used exclusively in some animals, including dogs. It has a mechanism of action similar to that of NSAIDs, as well as other unique characteristics. A variety of … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 4 · 2 Nov 2021 · 11,585 accessesView PDFCite
Research ArticleOpen accessIn the abstractFault-Tolerant Control of a Nonlinear Uncertain System: A Neural Network-Based Passive Approaches and Comparative Study with State-of-the-Art Control ApproachesSejal K. Raval, Himanshukumar Rajendrabhai Patel, Vipul A. ShahThis article suggests passive methods for designing Fault-Tolerant Control (FTC) for nonlinear uncertain systems with actuator and leak faults. To anticipate the Fault-Tolerant Control (FTC) action to overcome the actuator and leak faults, two-layer Feed-Forward Back-Propagation Neural Network (FFBPNN) and two-layer Cascade Forward Neural Network (CFNN) have been used, it will also tolerate external process additive disturbances. We employ the … …Journal of Computer Science, Vol. 17, Issue 7 · 3 Aug 2021 · 6,736 accessesView PDFCite
Review ArticleOpen accessIn the abstractDisinfection of Water using Supported Titanium Dioxide PhotocatalystsShamkumar Pandurang Deshmukh, Dattatray Krishna Dalavi, Yuvaraj Mohan HungeTiO2 based photocatalyst has potential material for disinfection of harmful pathogens as well as removal of organic compounds. The formation of reactive oxygen species is a key part for overall process but aggregation and band gap constraint explore a new dimension to use of support for propounding its physicochemical properties. Therefore, the modification of TiO2 using various support alters photocatalytic … …American Journal of Engineering and Applied Sciences, Vol. 13, Issue 4 · 28 Dec 2020 · 7,261 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Action of Bovine Cartilage on Tumor Cells In Vitro And In VivoArax Tanelian, Alexander M. AbdelnoorIn an earlier study we had investigated the effect of Bovine Cartilage (BC) on mouse melanoma cells. In pursuant to this study BC anti-tumor activity in vitro against several human tumor cell lines was evaluated, mechanism by which BC induces tumor cell death was studied and its immunogenicity was assessed. Five mice received Intraperitoneal (IP) injection of BC once every … …American Journal of Immunology, Vol. 14, Issue 1 · 23 Jan 2018 · 9,664 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractDynamics of Buses - Part IIIRelly Victoria Virgil Petrescu, Raffaella Aversa, Gheorghe Frăţilă et al.Dynamics, or dynamic processes, is the part of mechanics dealing with the study of processes trying to describe as real as possible the movement of a body, element, mechanism, car, etc., also taking into account the action of the forces on the respective system with their influence on the actual movement of system. The present paper aims to present the … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 20 Apr 2018 · 8,454 accessesView PDFCite