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288 articles for “Immune”

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Research ArticleOpen accessEvery word in the titleActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,780 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleRole of Galphaq Containing Protein in Immune RegulationYuan Liu, Lu Gan, Guixiu ShiG proteins, one of the most important transmembrane signal transducers, contain four subfamilies. Gαq is the α subunit of Gq protein subfamily. The Gαq containing protein initially attracted attention for its physiological significance is in cardiovascular system. In recent years, its role in immune regulation has been indicated. Studies domenstrated that Gαq plays crucial role in regulating both innate and … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,417 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAdaptation to High Grain Diets Proceeds Through Minimal Immune System Stimulation and Differences in Extracellular Matrix Protein Expression in A Model of Subacute Ruminal Acidosis in Non-lactating Dairy CowsB. W. McBride, O. AlZahal, M. A. Steele, L. DionissopoulosProblem statement: Subacute Ruminal Acidosis (SARA) is a metabolic disorder affecting approximately 20% of all dairy cattle in North America. Although the presence of SARA has been described for some time, the etiology of the disorder remains uncertain. For example, many animals diagnosed with SARA seem to remodel and adapt their epithelium to accommodate the stresses imposed by SARA, but … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 2 · 25 Jul 2012 · 8,118 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUnique Characteristic Features of Mycobacterium Tuberculosis in Relation to Immune SystemRajni, Laxman S. MeenaProblem statement: Tuberculosis is a leading global mortality factor which has not been effectively controlled, with 1.7 million deaths per year and 8.9 million new cases. Aerobic microbe Mycobacterium Tuberculosis H37Rv (MTB) is the causative agent of tuberculosis. Approach: It is unique among prokaryotes due to its exceptional features contributing to its survival within the hostile environment of macrophages. Results: … …American Journal of Immunology, Vol. 7, Issue 1 · 16 Aug 2011 · 17,211 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Artificial Immune System with Artificial Neural Network for Predicting Bombay Stock Exchange TrendsM. Gunasekaran, K. S. RamaswamiProblem statement: The purpose of this study is to develop an artificial immune system for recognizing stock market trends and predict upward and downward directions of stock market. This study compared two prediction models, an Artificial Immune System (AIS) and Artificial Neural Network (ANN) for predicting the future index value, trend of Indian stock market and discovers the best prediction … …Journal of Computer Science, Vol. 7, Issue 7 · 28 Jun 2011 · 7,075 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Efficient and Effective Immune Based ClassifierShahram Golzari, Shyamala Doraisamy, Md Nasir Sulaiman, Nur Izura UdzirProblem statement: Artificial Immune Recognition System (AIRS) is most popular and effective immune inspired classifier. Resource competition is one stage of AIRS. Resource competition is done based on the number of allocated resources. AIRS uses a linear method to allocate resources. The linear resource allocation increases the training time of classifier. Approach: In this study, a new nonlinear resource allocation … …Journal of Computer Science, Vol. 7, Issue 2 · 25 Feb 2011 · 7,768 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Salmonella enteritidis Outer Membrane Proteins and Lipopolysaccharide Profiles with the Detection of Immune Dominant ProteinsA. Maripandi, Ali A. Al-SalamahProblem statement: Salmonella infection is a serious medical and veterinary problem world-wide and causes great concern in the human health and food safety. Salmonella enteritidis outer membrane proteins and lipopolysaccharide play important role in the virulence and immunological properties of bacteria. Prophylaxis of enterobacterial infection has proven difficult to achieve. Vaccination is an effective tool for the prevention of Salmonella … …American Journal of Immunology, Vol. 6, Issue 1 · 21 Jun 2010 · 9,147 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Effect of Methionine and Threonine Supplementations on Immune Responses of Broiler Chickens Challenged with Infectious Bursal DiseaseElham Maroufyan, Azhar Kasim, Seyed Reza Hashemi et al.Problem statement: The aim of this study was conducted to determine the effects of supplementing methionine and threonine higher than the National Research Council (NRC) recommendation in the diets on immune responses of broiler chickens challenged with Infectious Bursal Disease (IBD). Approach: A total of 450 day-old male broiler chicks were assigned to one of the nine dietary treatments. Three … …American Journal of Applied Sciences, Vol. 7, Issue 1 · 31 Jan 2010 · 8,844 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCancer Chemotherapy and Immune RegulationJohn Barrett, Katarina Le BlancProblem statement: Chemotherapeutic drugs have been used to treat malignancy for over 50 years, but the potential of cytotoxic agents to suppress immunity and interfere with Immunosurveillance (IS) of cancer has been largely ignored. Assuming that the immune control of the cancer had a priori already failed, the effect was not considered to have a major impact on treatment outcome. … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 40,663 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleγ-Aninobutyric acid (GABA) suppresses antigen-specific immune responses in ovalbumin γ(OVA)-immunized BALB/c miceTohru Sakai, Hiroko Okada, Mitsuo Kise et al.γ-Aminobutruic acid (GABA) is known to be a ubiquitous inhibitory neurotransmitter in the central nervous system. Furthermore, recent studies have shown that GABA modulates cardiovascular and respiratory functions. In this study, we examined the effect of GABA on antigen (Ag)-specific immune responses and elucidated the mechanisms underlying those effects in ovalbumin (OVA)-immunized BALB/c mice. OVA-specific proliferative responses were decreased in … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,501 accessesView PDFCite