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34 articles for “IFN-γ”
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Literature ReviewOpen accessIn the abstractFundamental Questions about γδT CellsMoulay Yassine Belghali, Saadia Ba-M’hamed, Mouna Khouchani, Brahim AdmouγδT cells is a minor subgroup of T lymphocytes expressing γδ-T Cell Receptor (TCR), with many subsets, dominated by Vδ2 and Vδ1. γδT cells recognize antigens independently of the context of MHC class I, MHC class II, or CD1 presenting molecules. However, this recognition requires the expression of the transmembrane Butyrophilin proteins by the presenting cells. Their activation is controlled … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 15 Dec 2020 · 6,382 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunologic Aspect of Mice (Mus musculus) Dental Caries Induced by Streptococcus mutansSri MurwaniDental caries (tooth decay), cavities or caries is a breakdown of teeth due to activities of bacteria acid producing in the presence of fermentable carbohydrates. The most responsible bacteria for dental cavities are Streptococcus mutans. Dental shape, saliva pH, normal flora, diets were suggested as predisposition factors for dental plaque and caries. The aim of this research was to study … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 28 Mar 2017 · 8,123 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of Cytokines and Transcription Factors in Periodontitis: A Review of Cellular and Molecular MechanismsAnne Carolina Eleutério Leite, Valéria Martins de Araújo Carneiro, Júlia Faria Nunes et al.Periodontal Diseases (PD) are characterized by pathological manifestation of host immune response to bacterial infection at the tooth/gingival interface. Evidences points periodontitis as a risk factor for pathological systemic conditions, such as, cardiovascular diseases and diabetes. The identification of host factors that determine their susceptibility to immune subversion can provide useful information in the pathogenesis of periodontitis. Protective acute inflammatory … …American Journal of Immunology, Vol. 11, Issue 4 · 9 Dec 2015 · 7,807 accessesView PDFCite
Research ArticleOpen accessIn the abstractCD2 Shown to Facilitate CD4+ Cell Differentiation during Visceral Leishmaniasis, a Receptor Based StudySukrat Sinha, Shanthy Sundaram, Sanjiva Bimal et al.This study addressed the role of CD2 on CD4+ T helper cells in relation to the TCRVα1 and CD70 in two groups of BALB/c mice viz control and infected (1×107 L. donovani promastigotes). The results showed with the downregulation of CD2 expression there is a pronounced decrease of TCRVα1 and CD70 on CD4+ cells in mice. An insight into the … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 28 Nov 2015 · 7,828 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Affecting the Response to Interferon Alpha Therapy in Egyptian HCV PatientsNaglaa F. Alhusseini, Fathy M. Serry, Ashraf A. Kadry, Heba KhairyHepatitis C Virus (HCV) infection is one of the main causes of chronic liver disease worldwide. Egypt has the highest prevalence of Hepatitis C Virus (HCV) in the world, estimated nationally at 14.7%. knowledge of the predictors of Sustained Viral Response (SVR) to Pegylated Interferon (PEG-INF) and Ribavirin (RBV) therapy in patients with chronic hepatitis C is crucial for selecting … …American Journal of Immunology, Vol. 11, Issue 3 · 30 Sep 2015 · 6,619 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Potential of VipAlbumin® to Chronic Inflammation in Type 2 Diabetes Mellitus Balb/C Mice ModelDinia Rizqi Dwijayanti, M. Sasmito Djati, Mansur Ibrahim, Muhaimin Rifa’iDiabetes Mellitus (DM) is one of diseases which have increasing number of sufferers every year. Almost all DM patients are type 2 DM. One of the causes of type 2 DM is a chronic inflammation due to an increase of circulating proinflammatory cytokines such as TNF-α, IFN-γ and IL-6. VipAlbumin® from snakehead fish extract is expected to be useful as … …American Journal of Immunology, Vol. 11, Issue 2 · 13 Jul 2015 · 7,612 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Properties of Kaurenoic Acid on Macrophages of BALB/c in VitroJuliana Aparecida Macri, Suelen Santos da Silva, Milena Menegazzo Miranda et al.Kaurenoic acid has been displaying anti-inflammatory effect described in different models. However, the per se immunomodulatory effects of kaurenoic acid remain to be investigated. Thus, the immunomodulatory and antioxidant effects of kaurenoic acid were investigated in vitro on peritoneal macrophages from BALB/c mice. Kaurenoic acid induced per se the production of pro-inflammatory cytokines such as TNFα, IL-1β and IFN-γ while … …American Journal of Immunology, Vol. 10, Issue 4 · 16 Feb 2015 · 7,883 accessesView PDFCite
Research ArticleOpen accessIn the abstractDEVELOPMENT OF THE INNATE IMMUNE RESPONSE AND INFLUENCE OF COLOSTRUM SUCKLING IN CALVESViviani Gomes, Camila Costa Baccili, Vinicius Alvim Passos Baldacim et al.Bovine colostrum contains immune factors, like leukocytes and cytokines that are absorbed by the intestinal mucosa of the neonate, however, not much is known about the function of some of these components in the active immune response of calves. The aim of this study was to determine the influence of colostrum intake and development of the innate immune response of … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 2 · 14 Apr 2014 · 7,475 accessesView PDFCite
Research ArticleOpen accessIn the abstractASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Factors of Colostrum and Human Milk Exhibits a Day-Night VariationNubia Andrade Silva, Adenilda Cristina Honorio-Franca, Fernanda Regina Giachini et al.The aim of this study was to determine the chronobiological variations of cytokines (IFN-γ, TGF-β) and hormones (melatonin and cortisol). The sample was collected from 42 mothers at three stages of maturity-day 3 (colostrum), day 10 (transitional milk) and day 30 (mature milk) postpartum, at two times of day: diurnal (12:00 h) and nocturnal (24:00 h), resulting a total of … …American Journal of Immunology, Vol. 9, Issue 2 · 25 Jun 2013 · 8,186 accessesView PDFCite