54 articles for “IC50”

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Research ArticleOpen accessIn the abstractAntioxidant and Antibacterial Properties of Essential Oils from Citrus reticulata cv. Shatangju Peel for the Preservation of Chilled PorkYao Dong, Xintong Zou, Hongli Zhou et al.Citrus reticulata cv. Shatangju peel essential oil (CrspEo), with three major components D-limonene (88.15%), γ-terpinene (4.59%) and β-myrcene (2.62%), possessed antioxidant activities with DPPH and ABTS+ radical scavenging with the IC50 (concentration of CrspEo scavenging 50% of radical) of 9.87±0.12% and 0.48±0.02%, respectively. Meanwhile, CrspEo showed antimicrobial activity in suppressing the growth of Bacillus pumilus, Bacillus subtilis, Candida albicans, Escherichia … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 3 · 31 Jul 2024 · 4,748 accessesView PDF Cite

Research ArticleOpen accessIn the abstractUltrasound-Assisted Enzymatic Extraction of Polysaccharides from Waste Corn Bract: Process Optimization, Characterization, Antioxidant and Anti-Diabetic PotentialsYihui Liu, Yayi Li, Na Niu et al.Corn bract is the main agricultural waste of corn production and processing. Little information is focused on its value-added utilization. In the present study, the Ultrasound-Assisted Enzymatic Extraction (UAEE) was used for the first time to extract Corn Bract Polysaccharides (CBPs). The optimum conditions of UAEE for CBPs extraction were: Cellulase amount of 0.7%, enzymolysis for 58 min, and ultrasound … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 2 · 28 Jun 2022 · 6,126 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOptimization of Ultrasonic-Assisted Total Flavonoids Extraction from Flower of Albizia Julibrissin Durazz. by Response Surface Methodology for Characterization of Chemical Profile and Evaluation of Antioxidant and Tyrosinase Inhibitory ActivitiesYijie Cheng, Yuwen Zhang, Hanzhang Sun et al.To investigate the flavonoids in flower of Albizia julibrissin (‘He Huan Hua’ in Chinese), the ultrasonic-assisted extraction of total flavonoids from ‘He Huan Hua’ was optimized by response surface methodology and the chemical profile was characterized by HPLC- QTOF-MS/MS. What’s more, the antioxidant and tyrosinase inhibitory activities of ‘He Huan Hua’ were also evaluated in this study. The extraction time, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 14 Mar 2022 · 6,733 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCrude Extract of Blue-Green Pigment Derived from the Marine Bacterium Pseudomonas aeruginosa P1.S9 has Antibacterial, Antioxidant, and Cytotoxic ActivitiesAris Tri Wahyudi, Rahmah Nursari, Widya Esti Purwaningtyas et al.Pigment derived from marine bacteria is one of the alternative sources of natural products characterized by beneficial functions for pharmaceutical purposes. This study aimed to evaluate the antimicrobial, antioxidant and cytotoxic activities of the marine bacterium Pseudomonas aeruginosa P1. S9 crude pigment extract and identify its chemical content. Crude pigment extract of this bacterium showed promising antibacterial activities against Pseudomonas … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 4 Mar 2022 · 6,994 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,955 accessesView PDF Cite

Short CommunicationsOpen accessIn the abstractCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDF Cite

Research ArticleOpen accessIn the abstractOptimization of Purification Technology and Antioxidant Activity of Total Flavonoids from Sea Buckthorn LeavesJiale Shan, Yang Liu, Pu Zhao et al.China is rich in sea buckthorn (Hippophae rhamnoides L.)resources and a large amount of sea buckthorn fruit is used to extract oil andjuice every year. However, Sea Buckthorn Leaves (SBL), which are full offlavonoids, are discarded as waste. To make full use of resources and turn waste into valuables, theoptimal purification process of flavonoids from SBL was studied and theantioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 27 Aug 2022 · 6,073 accessesView PDF Cite

Research ArticleOpen accessIn the abstractPotency of Pepsin Soluble Collagen from Indonesian Local Goat Skin as an AntioxidantRina Wahyuningsih, Rusman, Nurliyani et al.Pepsin Soluble Collagen (PSC) hydrolyses is derived from the collagen extraction process from Indonesia local goat skin (Kacang) was carried out in some previous studies. This study is considering the first research used the collagen from the goat skin as an antioxidant compound. The main purpose of study were to investigate antioxidant activity of PSC hydrolysis after pepsin treatment. The … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 3 · 22 Aug 2021 · 7,516 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA Meat-Derived Lactic Acid Bacteria, Lactobacillus plantarum IIA, Expresses a Functional Parvulin-Like Protein with Unique Structural PropertyCahyo Budiman, Irma Isnafia Arief, Fernandes Opook, Muhammad YusufThe genome sequence of a Lactic Acid Bacterium (LAB) Lactobacillus plantarum IIA contains a single gene encoding a parvulin-like protein (Par-LpIIA). This protein belongs to Peptidyl Prolyl cis-trans Isomerase (PPIase) family proteins that catalyze a slow cis-trans isomerization of cis prolyl bond during protein folding. This study aims to provide molecular and biochemical evidences of the existence of Par-LpIIA in … …OnLine Journal of Biological Sciences, Vol. 21, Issue 1 · 26 Feb 2021 · 7,023 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSafe Ulvan Silver Nanoparticles Composite Films for Active Food PackagingHadear Hanie AminProtecting food from the corruption caused by different microbes is a big problem, as we need safe methods for food packaging. In this study, Ulvan (U), edible sulfated polysaccharide extracted from Ulva lactuca, was mediated for the first time non-toxic biosynthesized silver nanoparticles (Ag-NPs) to produce new and safe bio-nanocomposite films called (U/Ag-NPs) films for active food packaging. Ulvan was … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 28 Jan 2021 · 7,740 accessesView PDF Cite