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81 articles for “Flavonoid”
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Research ArticleOpen accessEvery word in the titleOptimization of Cellulase-Assisted Extraction of Total Flavonoids from Corn Bract and Evaluation of Antioxidant and Antibacterial AactivitiesYang Zhang, Jing Lu, Leijie Ben et al.Corn bract is a corn-based agricultural waste material that distributed worldwide. In present work, response surface methodology was applied to optimize the cellulase-assisted extraction of Total Flavonoids from Corn Bract (TFCB), the in vitro antioxidant and antibacterial as well as the in vivo antioxidant activities of TFCB were investigated. Results showed that the optimal conditions for TFCB extraction were as … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 2 · 18 May 2019 · 8,501 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleResponse Surface Optimized Ultrasonic Assisted Extraction of Total Flavonoids from Walnut Leaves and In Vitro Antibacterial ActivitiesYuanda Song, Aydin Berenjian, Han Wu et al.In this paper, the optimum extraction conditions of total flavonoids extracted from walnut leaves subjected to Ultrasonic Assisted Extraction (UAE) were optimized by Response Surface Methodology (RSM). The mathematical model showed the high coefficient of measurement (R2 = 0.9938) which indicated that this model could be used to guide the response surface methodology. The optimum extraction parameters for extracting flavonoids … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 24 Oct 2017 · 7,825 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,398 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,184 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleOptimization of Ultrasonic-Assisted Total Flavonoids Extraction from Flower of Albizia Julibrissin Durazz. by Response Surface Methodology for Characterization of Chemical Profile and Evaluation of Antioxidant and Tyrosinase Inhibitory ActivitiesYijie Cheng, Yuwen Zhang, Hanzhang Sun et al.To investigate the flavonoids in flower of Albizia julibrissin (‘He Huan Hua’ in Chinese), the ultrasonic-assisted extraction of total flavonoids from ‘He Huan Hua’ was optimized by response surface methodology and the chemical profile was characterized by HPLC- QTOF-MS/MS. What’s more, the antioxidant and tyrosinase inhibitory activities of ‘He Huan Hua’ were also evaluated in this study. The extraction time, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 14 Mar 2022 · 6,733 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Polarity of Organic Solvents in Coriander Seed Powder (Coriandrum Sativum) Extract is Dependent on their Content of Beta-Carotene, Total Phenolics, Flavonoids, Antioxidants, and Antibacterial PropertiesUcop Haroen, Syafwan, Agus Budiansyah, Kiki KurniawanAttempts to develop alternative antibiotics from herbal plants, especially those originating from spice plants that contain active compounds, are crucial to improve livestock health and support the growth of livestock to reach their genetic potential. This study aims to examine the effects of utilizing different solvent polarities on the solubility of coriander seed secondary metabolite chemicals, which are associated with … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 3 · 6 Nov 2025 · 2,332 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy of Ageratum conyzoides L. (Asteraceae) Phytochemical Composition as Quorum-sensing Inhibitors to Combat Antibiotic-resistant Bacterial InfectionsEli Compaoré, Lassané Ouedraogo, Ablassé Rouamba et al.The rise of antibiotic-resistant bacterial infections has intensified the search for plant-derived quorum-sensing (QS) inhibitors as alternative therapeutic strategies. Ageratum conyzoides L. has a long history of traditional use as an antimicrobial agent against multidrug-resistant pathogens, yet the phytochemical basis of its QS-inhibitory activity remains incompletely characterized. This study aimed to investigate the phytochemical composition of A. conyzoides and evaluate … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,772 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPotential of Fig Leaf (Ficus carica L.) as Immunomodulatory Agent in vitro and in SilicoAnita Dewi, Fitri Rahmayanti, Haidar Bagir et al.Natural remedies are increasingly being used as alternatives to conventional medicine, and their popularity is growing. The fig plant (Ficus carica L.), which is known to contain secondary metabolites such as alkaloids, flavonoids, phenolics, terpenoids, steroids, and saponins, has the potential to act as an immunomodulator. The purpose of this study was to determine the content of flavonoid compounds based … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 19 Jan 2023 · 6,232 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn silico Analysis of 4CL Family in Scutellaria baicalensis through Biocomputational Tools and ServersGuoming Li, Xiaozhong Lan, Xiaorong Shui et al.The gene sequences of 4-coumarate:coenzyme A ligase (4CL) family of Scutellaria baicalensis came from the GenBank Database. With help of some bioinformatics tools such as Vector NTI Suite 8, ProtParam and SWISS-MODEL and so on, a series of biological information of their nucleic acid sequences and amino acid sequences were predicted and analyzed and the results were revealed as following: … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 1 · 15 Feb 2017 · 7,864 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEXTRACTION OF QUERCETIN FROM POLYGONUM HYDROPIPER L. BY SUBCRITICAL WATERA. V. Lekar, S. N. Borisenko, E. V. Vetrova et al.The new method of quercetin extraction from Polygonum hydropiper L. by subcritical water was developed. High performance liquid chromatography was used for identification and quantification of flavonoids in the extract. The new method is environmentally friendly and more effective (7.6-times) than traditional flavonoids extraction methods using expensive and toxic organic solvents. …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 1 · 23 Nov 2013 · 8,612 accessesView PDFCite