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59 results for “Experimental Rats”
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Research ArticleOpen accessIn the abstractAlcohol Intubation and Synergistic Effect of Folic Acid and Egg Yolk Powder Solution on Alcohol Dehydrogenase [ADH] Class I Gene Expression and Single Nucleotide Polymorphism Frequency in Parent and Prenatal Alcohol Exposed Wistar RatsAdejoke Olukayode Obajuluwa, Oluyinka Ajibola Iyiola, Joseph Akintade Morakinyo et al.Point mutation detections in alcohol metabolizing genes could unravel molecular targets of gestational alcohol and epigenetic remodeling capacity of maternal nutrition, which underscores growth and health endpoints in Pre­natal Alcohol Exposed (PAE) fetuses. gene expression was assayed using sequenced target and internal control gene primers in a two-step thermal cycling process from isolated RNA in purely bred alcohol male and … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 22 Nov 2023 · 4,857 accessesView PDFCite
Research ArticleOpen accessIn the abstractAttempts to Stimulate Immunology Responses by Intramuscular and Intraperitoneal Delivery of EPS-Adjuvanted Mannheimiosis VaccineGhaith Hussein Mansour, Laith Abdul Razzak, Hassan Ibrahim Sheikh, Mohd Effendy Abd WahidThis study was conducted on 48 male Sprague Dawley rats to determine the immunological responses of experimental adjuvanted vaccines of Mannheimia haemolytica A2 (M. haemolytica A2) injection and to observe their protection level upon live M. haemolytica A2 challenge. Forty-eight clinically healthy Sprague Dawley rats were divided into four groups; Groups 1 and 2 were vaccinated intramuscularly and intraperitoneally, respectively, … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 4 · 22 Dec 2022 · 5,352 accessesView PDFCite
Research ArticleOpen accessIn the abstractCopper (I)-Nicotinate Promotes Gene Expression of CYPs that Produce M1 and Q1 in Aflatoxicosed RatsMohammed Salah, Laila Mostafa, Tahia H. Saleem et al.Aflatoxin-contaminated food poses a serious risk to both human and animal health. Copper (1)-nicotinate (Cu+-nicotinate) complex potentiated the prophylactic effect against chronic aflatoxicosis in the experimental animals through the synthesis of less toxic metabolites M1 and Q1 which are easily excreted in urine. To investigate the action of the safety Cu+-nicotinate complex on gene expression of Cytochrome 450 (CYP450) system, … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 28 Jan 2020 · 8,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Nutritional Quality of Some Wild Edible Plants in Central Cross River, NigeriaObi-Abang Magdalene, Margaret Akpana Agiang, Victor Eshu Okpashi, Godwin Eneji EgbungAccording to the Nigerian National Population Commission 2006, the population of the nation was conservatively estimated to be over one hundred and seventy million. The challenge of nutritional quality to feed an increasing national population places a higher demand on poorly grown conventional plants. Thus the need to incorporate wild edible plants to bridge the extended gap between the conventional … …American Journal of Applied Sciences, Vol. 15, Issue 6 · 11 May 2018 · 8,139 accessesView PDFCite
InvestigationOpen accessIn the abstractDevelopment of Genetic Constructions for Exctocytosis ControlIrina Nikolaevna Dominova, Vitaly Anvarovich Kasymov, Ekaterina Vladimirovna Silina et al.A fragment of the research project devoted to the development of genetic control of exocytosis is presented in the work, which can further ensure the success of targeted therapy of various diseases, including neurodegenerative ones. For the purpose of specific transfection of intracellular cascades in astrocytes in vivo, we have developed an experimental sample of the reagent kit. The latter … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 29 Jan 2018 · 7,310 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreventive Effect of Marsileacrenata Leaves and Stalks Juices Against Urolithiasis Showed by Improving of Kidney FunctionSri MurwaniNowadays urolithiasisis still as a major problem in pet animals, particularly for dogs and cats. Urolithiasisis caused by formation of crystals in the urinary tract that inhibit the process of urination. It is frequently as an impact of dry food given regularly, keeping animals in a place so that the movement of the animal becomes restricted, lack of water intake, … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 10 Feb 2016 · 9,305 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Galactomannan Extracted from Iraqi Lycium barbarum L. Fruits against Alloxan-Induced Diabetes in RatsAdnan J.M. Al-FartosyLycium barbarum L. (Solanaceae) is widely used in Iraqi Ayurvedic medicine for the treatment of diabetes mellitus. The present investigation was done to evaluate the effects of polysaccharide (galactomannan) from Lycium barbarum L. Fruits (GLBF) on serum blood glucose, serum lipid profile and lipid peroxidation and antioxidant defence system in liver and kidney of alloxan-induced diabetic rats. GLBF was found … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 15 Dec 2014 · 7,653 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Long Term Cadmium Chloride Exposure on Testicular Functions in Male Albino RatsRania Abdel Rahman Elgawish, Mohamed Elshabrawy GhanemThis study was carried out to investigate the adverse effects of different doses of Cadmium Chloride (CdCl2) on reproductive functions in male rats. Forty male albino rats weighted 100-130 g were equally divided into 4 groups. The control group received distilled water throughout the experimental period, while the three treated groups received 5, 50 and 100 ppm of CdCl2 in … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 10 Dec 2014 · 8,302 accessesView PDFCite
Research ArticleOpen accessIn the abstractCastration and Passive Avoidance Learning Alter the Distribution of N-Methyl D-Aspartate ReceptorSeyed Hassan Mirzaei, Mahnaz Taherianfard, Mina Tadjali, Mahbobeh KohkaloyehIn neurophysiological studies on learning and memory, L-glutamate receptors especially N-Methyl, D-Aspartate glutamate (NMDA) receptors have a major role in different aspect of the learning and memory. Two sites of mammalian brain that show high density of these receptors are CA1 region of hippocampus and Purkinje cell layer of cerebellum. Twenty four Sprague-Dawley rats were used in 4 groups: Control … …Neuroscience International, Vol. 4, Issue 2 · 1 Apr 2014 · 6,773 accessesView PDFCite
Research ArticleOpen accessIn the abstractREMEDIAL EFFECTS OF VITAMIN E AND L-ARGININE ON PERIPHERAL NEUROPATHY IN STREPTOZOTOCIN-INDUCED DIABETIC RATSIsmaeel Bin-Jaliah, Samah El-Attar, Eman F. Khaleel et al.It was shown that hyperglycemia in diabetic patients is the main factor of diabetic peripheral neuropathies. Various pathways related to oxidative stress, vascular defect and defective endothelium dependent relaxation have been implicated in the development of diabetic peripheral neuropathy. A substantial number of studies have shown that antioxidant treatment are promising therapeutics that can prevent or correct reduced motor nerve … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 23 Dec 2013 · 8,041 accessesView PDFCite