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97 articles for “Dose Dependent”

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Research ArticleOpen accessIn the abstractAccumulation and Effect of Manganese on Chloroplasts and Antioxidant Responses in Arabidopsis ThalianaJun Xing, Xue Yang, Cailing YuanIn this study, 5-day-old seedlings of Arabidopsis thaliana were exposed to 0, 0.5, and 1.0 mmol/L MnCl₂ for 6 days by using three independent biological replicates. The results indicated that Mn content in roots exhibited a dose-dependent increase with rising external Mn supply. The elevated Mn levels led to significant reductions in the nutrient content of K, Ca, Na, and … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 18 Jul 2026 · 836 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeed Treatment-Based Biocontrol of Tomato Damping off Using Plant Essential Oil and Green Silver NanoparticlesLaila Reklaoui, Zine El Abidine Bzazou Elouazzani, El Touhami Tayebi Ouazzani et al.The fungal pathogen Rhizoctonia solani is a major causal agent of damping-off in tomato plants, leading to severe yield losses worldwide. Conventional fungicides, while effective, raise concerns regarding environmental safety and human health, highlighting the urgent need for sustainable alternatives. In this study, we report for the first time the use of Origanum compactum essential oil to biosynthesize silver nanoparticles … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 2 Jun 2026 · 1,304 accessesView PDFCite
Research ArticleOpen accessIn the abstractThiosemicarbazide Induces Partial Myoclonic, Generalized Tonic-Clonic and Status Epilepticus Seizures Depending on the Dose in the RatAnwar Satef, Sofia El Amoury, Soumaya El Ganouni et al.The present study aimed to characterize the seizures produced by injections of Thiosemicarbazide (TSC), a glutamic acid decarboxylase inhibitor. It aimed also to evaluate the anticonvulsant effect of the antiseizure medications Phenobarbital (PHB), Valproate (VPA), and Phenytoin (PNT) and of the antipsychotics Chlorpromazine (CPZ) and Haloperidol (HAL) as well as the antidepressant SSRI, Fluoxetine (FXT). Male Wistar rats received TSC … …Neuroscience International, Vol. 13, Issue 1 · 4 Mar 2023 · 10,309 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhytochemical Composition, Antibacterial, and Antioxidant Properties of Foeniculum vulgare Essential OilSaif M. Dmour, Saqr Abushattal, Sultan Ayesh Mohammed Saghir et al.This study intended to inspect the phytochemical composition and bioactivity of Fennel (Foeniculum vulgare) Seed Essential Oil (FSEO) from Jordan. The EO was extracted via hydrodistillation from air-dried samples with 4.42% (v/w) yield. Twenty compounds, constituting around 98.5% of the EO were identified using Gas Chromatography-Mass Spectrometry (GC-MS). Estragole (47.15%) and Anethole (36.2%), appeared as predominant oxygenated monoterpenes compounds in … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 1 Aug 2025 · 4,640 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeparation, Purification and Anti-aging Activity of Tobacco PolysaccharidesMengyue Huang, Jingwu Song, Shuaishuai Chang et al.To separate tobacco polysaccharides and investigate their antioxidant and anti-aging properties, crude tobacco polysaccharides were extracted from raw tobacco using hot water, followed by purification through DEAE-52 cellulose column chromatography. The molecular weight and monosaccharide composition of the isolated polysaccharides were analyzed using HPGPC and HPLC. The antioxidant activities of these tobacco polysaccharides were tested using DPPH, ABTS, hydroxyl radicals … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 15 Jan 2025 · 5,108 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Preparation Procedures of Phlorizin-Zn (Ⅱ) Complex and Its Antioxidant Activity Study in vitroYuqing Zhang, Yaping Li, Guorui Yang et al.Flavonoid metal complexes possess more effective antioxidant properties than flavonoids. However, the preparation of the phlorizin-Zn (Ⅱ) complex and its antioxidant activity has not been reported. In this research, the preparation procedures of the phlorizin-Zn (Ⅱ) complex were enhanced using by single factor test and Response Surface Methodology (RSM). The optimal preparation procedures of the phlorizin-Zn (II) complex were as … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 3 Apr 2024 · 4,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic and Acute Effect of Tramadol Intoxication on Some Immunological ParametersLoveday Udu Zebedee, Zaccheus Awortu Jeremiah, Nyebuchi Jonathan, Eni-Yimini Solomon AgoroTramadol intoxication is rapidly on the increase in Nigeria with unestablished short-term and long-term effects. The study was aimed at elucidating the dose-dependent effect of acute or chronic tramadol intoxication on some immunological parameters using male rats (Rattus norvegicus). A total of fifty adult rats were used for the study as indicated by Mead's Resource Equation. The study consisted of … …American Journal of Immunology, Vol. 17, Issue 1 · 24 Apr 2021 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibitory Effect of Crude Walnut Leaf Polysaccharides on Oxidative Damage of Proteins and Proliferation of SGC-7901 CellsShuqing Yang, Zhike Xie, Shuyan Yu et al.In this paper, we studied the inhibitory effect of crude Walnut Leaf Polysaccharides (WLP) on free radical-induced oxidative damage of proteins and anti-proliferation activity on human Gastric Cancer cells (SGC-7901). The oxidative degradation of Bovine Serum Albumin (BSA), mouse brain proteins (MBP) and Mouse Liver Proteins (MLP) induced by hydroxyl radical and alcoxyl radical was analyzed by Sodium Dodecyl Sulfate-Polyacrylamide … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 26 Apr 2020 · 7,061 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Cinnamomum cassia Stem-Bark Extracts on the Synthesis and Secretion of Insulin in RIN-m5F CellsAnanias Hodi Kgopa, Sebolaishi Doris Makhubela, Motetelo Alfred Mogale, Leshweni Jerry ShaiCinnamomum cassia (C. cassia) crude stem-bark extracts possess some hypoglycemic properties through inhibiting the uptake of glucose by the intestines and/or enhancing insulin sensitivity. To further investigate the mechanism through which the hypoglycemic effect is exerted, this research explored the influence of the extracts of the crude stem-bark of C. cassia, with various polarities, on particular aspects of glucose consumption … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 5 Apr 2022 · 5,788 accessesView PDFCite
Research ArticleOpen accessIn the abstractCrude Extract of Blue-Green Pigment Derived from the Marine Bacterium Pseudomonas aeruginosa P1.S9 has Antibacterial, Antioxidant, and Cytotoxic ActivitiesAris Tri Wahyudi, Rahmah Nursari, Widya Esti Purwaningtyas et al.Pigment derived from marine bacteria is one of the alternative sources of natural products characterized by beneficial functions for pharmaceutical purposes. This study aimed to evaluate the antimicrobial, antioxidant and cytotoxic activities of the marine bacterium Pseudomonas aeruginosa P1. S9 crude pigment extract and identify its chemical content. Crude pigment extract of this bacterium showed promising antibacterial activities against Pseudomonas … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 4 Mar 2022 · 6,998 accessesView PDFCite