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75 articles for “Disease Progression”
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Research ArticleOpen accessIn the abstractPost-COVID Impact Analysis and Effective Recommendation Solutions Over Risk Prediction Using Hybrid ModelBoddeti Jaggan Mohan Ravi Kumar, P. V. G. D. Prasad Reddy, G SrinivasThe COVID-19 pandemic (2019-2022) resulted in significant global mortality, largely attributed to the virus's unpredictable pathophysiology, rapid disease progression affecting multiple organ systems, and initial lack of effective treatments. This study systematically examines post-COVID-19 complications across major organ systems, including respiratory dysfunction, cardiovascular complications, renal disorders, musculoskeletal pain, gastrointestinal disturbances, neurological sequelae, alopecia, endocrine and metabolic dysregulation, and mental health … …Journal of Computer Science, Vol. 21, Issue 11 · 23 Dec 2025 · 1,643 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Vertical Stacking-Based Ensemble Deep Learning Model for Early Diagnosis of Alzheimer's Disease Using Multimodal MRI ScansParvatham Niranjan Kumar, Lakshmana Phaneendra MaguluriEarly detection of Alzheimer's Disease (AD) is crucial for timely interventions that can slow disease progression, enhance quality of life, and assist with future planning. Convolutional Neural Networks (CNNs) are an efficient method for processing image-based data. In this work, we used CNN-based deep learning models to extract structural information from structural MRI (sMRI) and brain neuron connectivity patterns from … …Journal of Computer Science, Vol. 21, Issue 6 · 14 Jun 2025 · 3,099 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Analysis on Prediction of Chronic KidneyDisease by various Machine Learning ModelsNikhil Verma, Tripti Sharma, Bobbinpreet Kaur, Ayush DograChronic Kidney Disease (CKD) is a prevalent global healthconcern, which is affecting a number of people in the whole world. Earlydetection & precise checking of CKD are really important for essentialsupervision & intervention to prevent disease progression and associatedcomplications. Machine learning (ML) models have emerged as favourabletools for CKD detection due to their ability to analyse complex data patternsand provide … …Journal of Computer Science, Vol. 21, Issue 6 · 24 May 2025 · 5,939 accessesView PDFCite
Literature ReviewOpen accessIn the abstractUnraveling Sterile Inflammation in Atherosclerosis: Mechanisms, Implications and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Atherosclerosis, a leading factor in the development of cardiovascular diseases, is a complex and multifaceted condition with inflammation emerging as a pivotal determinant of its pathogenesis. This review comprehensively investigates the role of sterile inflammation in atherosclerosis and deliberates on potential therapeutic interventions targeting this underlying mechanism. Despite advancements in the understanding of atherosclerosis, diagnosing, preventing, and choosing effective treatment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 4 Mar 2025 · 3,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Research Progress on Peanut Disease and Insect Pest Control Based on VOS ViewerPing Dong, Fei Peng, Yizhe Zhang et al.Peanut cultivation spans across more than 100 countries globally as a vital oilseed crop. Nevertheless, the menace of pests and diseases poses a threat to peanut yield and quality, consequently impeding economic prosperity. To delve into the current research landscape concerning peanut disease and pest control, this study adopts a bibliometric methodology and employs a VOS viewer for multidimensional visualization … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 5 Nov 2024 · 4,034 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Effect of Main Heat Shock Proteins on AtherosclerosisAnastasia Vladimirovna Poznyak, Alexey V. Churov et al.Atherosclerosis is a multifaceted disease characterized by complex pathogenesis involving diverse mechanisms. In recent years, the autoimmune nature of atherosclerosis has gained significant attention, emphasizing the indispensable role of the immune system in its initiation and progression. Heat Shock Proteins (HSPs) are vital for cellular functionality, facilitating cellular adaptation to environmental changes and survival under adverse conditions. Notably, various HSP … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 3 Oct 2024 · 4,354 accessesView PDFCite
Review ArticleOpen accessIn the abstractCirculating Immune Complexes as an Important Link between Inflammation and Lipid Alterations in AtherosclerosisAnastasia Vladimirovna Poznyak, Nikolay Alexandrovich Orekhov, Vasily Nikolaevich Sukhorukov et al.This review article rigorously investigates the emerging facets of atherosclerosis pathogenesis through an exhaustive examination of the existing data on the intricate interplay between lipid metabolism disorders and inflammation. A primary objective of this study is to thoroughly explore the role of Circulating Immune Complexes (CIC) as a pivotal indicator of this multifaceted interaction. The focus of this review centers … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 14 Aug 2024 · 3,926 accessesView PDFCite
Review ArticleOpen accessIn the abstractVLDL in Atherosclerosis: Variety of Mechanistic ImplicationsAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Very-Low-Density Lipoprotein (VLDL) particles play a pivotal role as precursors for Intermediate-Density Lipoprotein (IDL) and eventually transform into Low-Density Lipoprotein (LDL). These particles have been categorized based on size and particle charge. Various types of VLDL impact diverse physiological processes in the human body. The accumulation of VLDL, along with other triglyceride-rich lipoproteins, significantly contributes to the development of atherosclerotic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 29 Jul 2024 · 4,308 accessesView PDFCite
Research ArticleOpen accessIn the abstractMMP-9 is a Potential Prognostic Marker of Left Ventricular Remodeling in Patients with Coronary Artery DiseaseMikhail Aleksandrovich Popov, Anastasia Vladimirovna Poznyak, Dmitry Valerievich Shumakov et al.Matrix Metalloproteinase-9 (MMP-9) emerges as a promising prognostic marker for assessing left ventricular remodeling in patients with coronary artery disease, particularly in the context of Ischemic Heart Disease (IHD) complicated by left ventricular aneurysm. In this study, we conducted two parallel investigations to explore the prognostic significance of MMP-9 in patients with multivessel coronary artery disease undergoing left ventricular reconstruction … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 11 Jul 2024 · 4,310 accessesView PDFCite
Review ArticleOpen accessIn the abstractOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,675 accessesView PDFCite