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Research ArticleOpen accessIn the abstractA General Strategy to Enhance Upconversion luminescence in Rare-Earth-Ion-Doped Oxide NanocrystalsGuanying Chen, Lei XuWe report a general strategy to enhance upconversion luminescence from rare-earth-doped oxide nanocrystals through tailoring the local crystal filed around rare earth ions. We show that upconversion luminescence from oxide nanocrystals of various host lattice (Y2O3, Gd2O3 and ZnO) and of diverse rare-earth-ions (such as Er3+, Yb3+/Er3+, Yb3+/Ho3+ and Yb3+/Tm3+) was enhanced by orders of magnitude through an introduction of … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 1 · 18 Feb 2016 · 7,741 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Hypoxia-Inducible Factor-1α Signaling Pathway and its Relation to Cancer and ImmunologyBruno R.B. Pires, Andre L. Mencalha, Gerson M. Ferreira et al.Hypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is present in all metazoans from early embryonic development throughout adult life. It plays a major roles in the different stress responses that are triggered by low Oxygen (O2) levels and its expression is associated with cell survival. HIF-1 is a heterodimer protein that comprises the subunits HIF-1α and HIF-1β. The … …American Journal of Immunology, Vol. 10, Issue 4 · 17 Jan 2015 · 8,485 accessesView PDFCite
Research ArticleOpen accessIn the abstractPREDICTION OF GLIOMA USING GENETIC OPTIMIZED NEURAL NETWORKS. Karpagam, S. GowriNeural networks are a computational paradigm model of the human brain that has become popular in recent years. We have tried to address the problem of Glioma by creating a more accurate classifier which can act as an expert assistant to medical practitioners. Brain stem gliomas are now recognized as a heterogenous group of tumors. In this study proposed a … …Journal of Computer Science, Vol. 9, Issue 11 · 1 Oct 2013 · 6,697 accessesView PDFCite
Research ArticleOpen accessIn the abstractGAUSSIAN MIXTURE MODEL BASED CLASSIFICATION OF MICROCALCIFICATION IN MAMMOGRAMS USING DYADIC WAVELET TRANSFORMSuman Mishra, Hariharan RanganathanBreast cancer is a serious health related issue for women in the world. Cancer detected at premature stages has a higher probability of being cured, whereas at advanced stages chances of survival are bleak. Screening programs aid in detecting potential breast cancer at early stages of the disease. Among the various screening programs, mammography is the proven standard for screening … …Journal of Computer Science, Vol. 9, Issue 10 · 5 Sep 2013 · 6,873 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Mechanisms in Hepatitis C Virus-Associated Hepatocellular Carcinoma: A Potential New Link Between Stem Cells, Virology and CancerQinghua Feng, Sajida Hassan, Trina Das et al.Recent studies suggest that epigenetic mechanisms are not only essential for the dynamic transcriptional regulation in embryonic and somatic stem cells, but are also actively involved in tumorigenesis: genes important for pluripotency are epigenetically regulated and aberrant epigenetic changes have been detected in virtually all human malignancies studied, including Hepatocellular Carcinoma (HCC). Infection with Hepatitis C Virus (HCV) is a … …Current Research in Medicine, Vol. 4, Issue 1 · 12 Mar 2013 · 8,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractCancerous Immunoglobulins and CA215: Implications in Cancer ImmunologyGregory LeeImmunoglobulins are typically expressed by B cells in our normal immune system. However, certain normal human tissues, such as hyperplastic epithelial cells, cells of the immunologically privileged sites and the majority of cancer cells, have also been found to be sites of immunoglobulin production. Current research is lacking in regards to the differential immunoglobulin expression, the underling mechanisms of action … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Sep 2012 · 8,946 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrornas are Not That Small to IgnoreSanjeev Kumar Srivastava, Sonal Somvanshi, Vivek Pratap SinghMicroRNAs (miRNAs) are small, noncoding RNA molecule that negatively regulates gene expression by causing either degradation or translational inhibition of their target mRNAs. These miRNAs are key regulators of various biological processes such as differentiation, maturation and maintenance of immune homeostasis. Furthermore, deregulated expression of miRNA has now been shown to regulate several disease processes by regulating tumorigenesis, angiogenesis, apoptosis … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 8,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross Validation Evaluation for Breast Cancer Prediction Using Multilayer Perceptron Neural NetworksShirin A. Mojarad, Satnam S. Dlay, Wai L. Woo, Gajanan V. SherbetProblem statement: The presence of metastasis in the regional lymph nodes is the most important factor in predicting prognosis in breast cancer. Many biomarkers have been identified that appear to relate to the aggressive behaviour of cancer. However, the nonlinear relation of these markers to nodal status and also the existence of complex interaction between markers have prohibited an accurate … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 4 · 20 Feb 2012 · 7,703 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impact of Air Pollution on Human Health: Focusing on the Rudnyi Altay Industrial AreaVitaliy G. Salnikov, Marat A. KaratayevProblem statement: Air pollution in Kazakhstan is significant environmental problem. The air pollution level of cities and industrial centers remains rather high. The highest level of air pollution is registered in Ridder, Ust-Kamenogorsk, Almaty, Zyryanovsk, Aktau, Atyrau, Shymkent, Taraz, Petropavlovsk and Temirtau. The enterprises of the Rudnyi Altay, Pavlodar Oblast and enterprises of oil and gas complex in West-Kazakhstan, Atyrau … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 21 Jul 2011 · 10,451 accessesView PDFCite