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1,656 results for “LU/LC Change”
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Research ArticleOpen accessIn the abstractImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,245 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effects of Chinese Traditional Processing Method on Components in Semen Sinapis AlbaeLifang Liu, Hui Zhou, Suqin Sun et al.Techniques of infrared (IR) spectrophotometry, High Performance Liquid Chromatography (HPLC) and HPLC-mass spectrometry are employed in this study to reveal the changes of the components in Semen sinapis Albae during the Chinese traditional processing. While the degradation of proteins and polysaccarides can be observed, sinapine in this drug can be known to decompose immediately after 15 mins during processing. A … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 6,810 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Reversible Method of Epiphysiodesis-An Experimental Study in RabbitsMahmood Karimi-Mobarakeh, Reza Malekpour-Afshar, Nozar Nakhaee et al.Lower limb discrepancy and angular deformities are among the most common orthopedic problems in pediatrics. All methods for correction of these deformities are irreversible and the epiphyseal growth plate is arrested. Current study describes a new reversible method of epiphysiodesis. At the first step, we decided to examine angular deformity of the knee. Seven New Zealand white female rabbits with … …American Journal of Applied Sciences, Vol. 2, Issue 6 · 30 Jun 2005 · 7,204 accessesView PDFCite
Research ArticleOpen accessIn the abstractIncreasing the Strength of Standard Involute Gear Teeth with Novel Circular Root Fillet DesignV. Spitas, Th. Costopoulos, C. SpitasIn this study the idea of spur gear teeth with circular instead of the standard trochoidal root fillet is introduced and investigated numerically using BEM. The strength of these new teeth is studied in comparison with the standard design by discretizing the tooth boundary using isoparametric Boundary Elements. In order to facilitate the analysis the teeth are treated as non-dimensional … …American Journal of Applied Sciences, Vol. 2, Issue 6 · 30 Jun 2005 · 7,586 accessesView PDFCite
Research ArticleOpen accessIn the abstractSupporting the Josephson Interpretation of Low Energy Nuclear Reactions and Stabilization of Nuclear WasteF. Osman, H. Hora, X. Z. Li et al.Brian Josephson appealed at the meeting of the Nobel Laureates July 2004 against the ignorance of physicist to the phenomenon of cold fusion. Though there are good reasons against many publications on this topic but not for all what was reported. It seems to be indicated to summarize the following serious, reproducible and confirmed observations on the reactions of protons … …American Journal of Applied Sciences, Vol. 2, Issue 6 · 30 Jun 2005 · 7,162 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Study for Allocating Resources in Research and Development Programs by Integrated Subjective and Objective Decision MethodChun-Chu LiuA decision model is developed to help managers select the most appropriate sequences of plans for product Research and Development (R and D) projects that have strict constraints on budget, time, and resources. In recent years, many organizations have changed from a discipline orientation to a focus on integrated programs and related outcomes. For decision-maker of these high-profile R and … …American Journal of Applied Sciences, Vol. 2, Issue 5 · 31 May 2005 · 7,268 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of the Mass Transfer Process in Oil SpillFabián Betancourt, Arturo Palacio, Alejandro RodriguezA revision of the models used to study the behavior of the mass loss processes associated with petroleum spills on water and to compare those models with experimental data. The processes of mass transfer studied in this work are evaporating, dissolution, vertical dispersion, emulsification and the changes of properties associated with these. The comparison of the estimations with the field … …American Journal of Applied Sciences, Vol. 2, Issue 5 · 31 May 2005 · 7,502 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Evolution of Today's Health Care EconomyEldo E. Frezza, Maurizio Chiriva-InternatiThe health care economy has fluctuated in the last 30 years. One of the contributing factors has been the reimbursement schemes used by hospitals and physicians, which has had a considerable impact on the behavior and performance of the health care market. Unlike health care markets in other countries, the U.S. has a multi-payer system. These third-party payers include the … …Journal of Social Sciences, Vol. 1, Issue 1 · 31 Mar 2005 · 6,655 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign and Analysis of a Smart Multi Purpose Electronic Nose SystemMahmoud Z. Iskandarani, Nidal F. ShilbayehAn electronic nose system for multi application purposes is designed and tested. Our hardware design allows various types of sensors to be used for different applications. The system is capable of being interfaced to both analog and digital instruments with special filtering devices that isolate the system from surrounding signals. The design of the system is distinguished through the use … …Journal of Computer Science, Vol. 1, Issue 1 · 31 Mar 2005 · 6,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractInteraction of a C-terminal Truncated Hepatitis C Virus Core Protein with Plasmid DNA Vaccine Leads to in vitro Assembly of Heterogeneous Virus-like ParticlesNelson Acosta-Rivero, Joanna Poutou, Alexis Mussachio et al.Recently, it has been shown that HCV core proteins (HCcAg) with C-terminal deletions assemble in vitro into virus-like particles (VLPs) in the presence of structured RNA molecules. Results presented in this work showed that a truncated HCcAg variant covering the first 120 aa (HCcAg.120) with a 32 aa N-terminal fusion peptide (6xHistag-XpressTMepitope) interacts with plasmid DNA vaccine. Interestingly, the buoyant … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,754 accessesView PDFCite