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175 articles for “Susceptibility”
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Research ArticleOpen accessIn the abstractMelanoma-Associated Suppression of the Dendritic Cell Lines DC2.4 and JawsiiKristian Michael Hargadon, Yonathan Tarekegne Ararso, Osric Anthony Forrest, Chad Mason HarteDendritic cells function as potent regulators of both innate and adaptive immunity to tumors and the regulatory activities of these cells are tightly linked to their maturation and activation status. Despite the critical role played by dendritic cells in the induction of anti-tumor immune responses, the number of dendritic cells that can be isolated from experimental animals is limiting and … …American Journal of Immunology, Vol. 8, Issue 4 · 3 Nov 2012 · 9,567 accessesView PDFCite
Research ArticleOpen accessIn the abstractCell-Based Therapies in the Prevention of Solid Organ Transplant RejectionAdrian E. Morelli, Sherrie J. DivitoProblem statement: Organ transplantation is a life-saving and increasingly common procedure, as it often serves as the only treatment available for end-stage organ disease. Although the constant development of new and more effective immunosuppressive drugs has revolutionized the prevention and treatment of acute graft rejection, these drugs have significant toxicity, greatly increase patient susceptibility to neoplasms and infection and exert … …American Journal of Immunology, Vol. 8, Issue 2 · 26 Jul 2012 · 7,418 accessesView PDFCite
Research ArticleOpen accessIn the abstractHigh-Order Interactions in Rheumatoid Arthritis Detected by Bayesian Method using Genome-Wide Association Studies DataJing Zhang, Zheyang Wu, Chao Gao, Michael Q. ZhangProblem statement: In order to reveal the missing genetic component of Rheumatoid Arthritis (RA) susceptibility, we carried out a genome-wide high-order epistatic interaction study for RA. Approach: A powerful Bayesian strategy was applied to analyze the data of Genome-Wide Association Studies (GWAS) from the Welcome Trust Case Control Consortium (WTCCC), where 319 high-order interactions were found across the whole genome … …Current Research in Medicine, Vol. 3, Issue 1 · 30 Mar 2012 · 8,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractNew Lines of Chickpea Against Fusarium Oxysporum f. sp. Ciceris WiltRosa Marina Arvayo-Ortiz, Martin Esqueda, Evelia Acedo-Felix et al.Problem statement: In Mexico, 70 and 20% of chickpea is produced in Sinaloa and Sonora, respectively. In Sonora wilting by Fusarium Oxysporum f. sp. Ciceris (FOC) causes losses of up to 60%, while in other parts of the world ranged from 12-15% annually. The aim of this study was to evaluate the resistance of new lines of chickpea obtained through … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 7,555 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Polymorphisms in the Fat Mass and Obesity-Associated Gene Confers Risk of Obesity in Iraqi PopulationShatha Ramadhanzaidan, Faris Abd Al Kareem, Lujain Anwar AlkhazrajyProblem statement: Obesity is strongly influenced by genetic factors, with an estimated heritability of 60% BMI. Genetic susceptibility to the common form of obesity appears to be polygenic. Although theoretical analyses emphasized the power of genetic association study in common polygenic diseases, the search for genes conferring the risk of obesity has thus far not been very successful. Approach: In … …American Journal of Infectious Diseases, Vol. 7, Issue 2 · 21 Sep 2011 · 7,624 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuppression of Salicylic Acid-Mediated Plant Defense Responses During Initial Infection of Dyer's Woad by Puccinia thlaspeosBradley R. Kropp, Elizabeth ThomasProblem statement: Puccinia thlaspeos is a microcyclic rust pathogen that is being investigated as a potential biocontrol agent of the noxious weed, dyer’s woad (Isatis tinctoria). Although, the initial events in the colonization of dyer’s woad by the rust pathogen has been elucidated using scanning electron microscopy and PCR, little is known regarding the susceptibility response of this plant to … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 3 · 4 Aug 2011 · 8,035 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of organic wax on bitumen characteristicsArafat Suleiman Yero, Mohd Rosli HaininStatement problem: The study investigated effect of organic wax Sasobit wax (S) on the characteristics of bitumen 80/100-penetration grade. The consistency of bitumen is measure of its susceptibility to temperature change and resistance to flow which affects ability and resistance to deformation of the mixture. Approach: This study reviewed the bitumen modification process in relation to Warm Mix Asphalt (WMA) … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 2 · 13 Jul 2011 · 8,021 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntimicrobial Pattern and Clonal Dissemination of Extended-Spectrum Beta-Lactamase Producing Klebsiella Spp IsolatesSobhan Ghafourian, Nourkhoda Sadeghifard, Zamberi bin Sekawi et al.Problem statement: Gram-negative pathogens harboring ESBLs have caused numerous outbreaks of infections and are becoming an increasing therapeutic problem in many countries. The incidence of ESBL-producing strains among clinical isolates has been steadily increasing over the past years resulting in limitations of therapeutic option. The focus of this study was to examine the molecular epidemiology of ESBL-producing Klebsiella spp, investigate … …American Journal of Infectious Diseases, Vol. 6, Issue 4 · 31 Dec 2010 · 7,900 accessesView PDFCite
Research ArticleOpen accessIn the abstractField Assessment of Anthracnose Disease Response for the Sorghum Germplasm Collection from the Mopti RegionJ. E. ErpeldingProblem statement: Sorghum anthracnose (Colletotrichum sublineolum) is a highly variable pathogen and new sources of host plant resistance are required for the development of resistant sorghum varieties. Germplasm collections are an important source of host plant resistance and screening germplasm will be essential to identify new sources of resistance. Approach: The sorghum (Sorghum bicolor) collection from the Mopti region of … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,217 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Municipal Solid Waste Compost on the Growth and Production of Vegetable CropsA.E. Ghaly, F.N. AlkoaikProblem statement: MSW has traditionally been dealt with thorough the practice of land filling and incineration. However, deleterious environmental impacts have promoted municipalities in Canada to recycle non-putrescible wastes and compost the putrescible ones. This study aimed at evaluating the effect of MSW compost on the growth and production of three vegetable crops (potatoes, corn and squash). Approach: Each crop … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,799 accessesView PDFCite