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158 results for “genetic analysis”
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Research ArticleOpen accessIn the abstractModern Metaheuristic with Multi-Objective Formulation for the Variable Selection ProblemLauro Cassio Martins de Paula, Anderson da Silva Soares, Telma Woerle Soares et al.The development of efficient algorithms for variable selection becomes important to deal with large and complex datasets. Most works in quantitative chemical analysis have used Genetic Algorithms (GAs) as a reference method to select variables. On the other hand, new advances in metaheuristic techniques provide novel possibilities in this task Moreover, the application of Multi-Objective Optimization (MOO) may significantly contribute … …Journal of Computer Science, Vol. 13, Issue 11 · 20 Nov 2017 · 7,661 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Integrative Approach to the Study of Individuality of Subjects of Educational Activity in the Ontogeny from the Positions of Sex and GenderLubov Vladimirovna MishchenkoScientists are trying to study the peculiarities of men and women by adding biological and social components of the human, however since gender is not the natural givenness, but a social construct assuming self-awareness and self-determination, the connections between these components will be refracted through a variety of conditions. The purpose of the article is an integrative study of non-linear … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 27 May 2016 · 7,329 accessesView PDFCite
EditorialOpen accessIn the abstractVisceral Pain: Basic Research Concepts and Therapeutic InterventionsVictor V. ChabanThe accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors … …International Journal of Research in Nursing, Vol. 6, Issue 2 · 26 Aug 2015 · 7,148 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of miRNAs in Introns and Cis-Regulatory Regions of Genes of the Somatotropic Axis in MammalsTatiana Shkurat, Dmitry Romanov, Evgeny Pshenichnyy et al.To understand the role of microRNA in genetic control of animal growth mechanisms, we performed bioinformatic analysis of the localization of microRNAs in introns and cis-regulatory regions of the somatotropic axis genes-GH1, GHRH, SST and IGF1 in Homo sapiens, Macaca mulatta, Pan troglodytes, Pongo abelii, Gorilla gorilla, Ovis aries, Bos Taurus, Loxodonta Africana, Oryctolagus cuniculus, Canis lupus, Rattus norvegicus and … …American Journal of Applied Sciences, Vol. 12, Issue 1 · 26 Jan 2015 · 7,015 accessesView PDFCite
Research ArticleOpen accessIn the abstractMOLECULAR CHARACTERIZATION ON THE BASIS OF HA, NA AND M GENE REVEALED CHANGES IN CRITICAL AMINO ACID POSITIONS OF INFLUENZA A (H3N2) VIRUS CIRCULATING IN INDIA DURING 2011-2013Sachin Kumar, Shashi Khare, Bano Saidullah et al.Influenza a (H1N1) virus is responsible for acute respiratory infection in human, which occasionally causes epidemic and rarely a pandemic. Full length DNA sequencing of HA, NA and M gene of H3N2 virus from year 2011-2013 was performed for determination of the circulating strains in India along with monitoring status of various mutations associated with drug resistance and virulence. Genetic … …American Journal of Infectious Diseases, Vol. 10, Issue 3 · 18 Oct 2014 · 6,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractA NAPIN PROMOTER ACTIVATES GENE EXPRESSION IN DEVELOPING SEEDS OF LESQUERELLA FENDLERIGrace Q. Chen, Jiann-Tsyh LinLesquerella fendleri produces industrial useful Hydroxy Fatty Acids (HFA) in seed oil. To improve oil and HFA of L. fendleri, it is desirable to use of seed-specific promoters to control the expression of target genes by genetic engineering. A seed-specific promoter fragment, -397 to -1 of a napin gene (PnapA) from Brassic napus was isolated by PCR and constructed to … …OnLine Journal of Biological Sciences, Vol. 12, Issue 3 · 18 Sep 2012 · 7,890 accessesView PDFCite
Research ArticleOpen accessIn the abstractTransformation of Lesquerella Fendleri with the New Binary Vector pGPro4-35SGrace Q. Chen, Roger Thilmony, Jiann-Tsyh LinProblem statement: Crop genetic engineering requires the use of various promoters to control the expression of introduced transgenes. Some of the binary vectors currently available for promoter characterization in dicotyledonous plants have pitfalls due to their construction, such as containing a selectable marker cassette with enhancer sequences that can potentially interfere with the expression specificity of nearby promoters. Also, many … …OnLine Journal of Biological Sciences, Vol. 11, Issue 3 · 19 Jan 2012 · 7,425 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Prospective Evaluation of Antihypertensive Medications Safety and Efficacy in United Arab Emirates Private HospitalsMuaed Jamal Alomar, Claire Caroline StrauchProblem statement: Hypertension is one of the most important risk factors for heart and cardiovascular diseases in the United Arab Emirates (UAE). Evaluation of the safety and efficacy of antihypertensive medications in UAE private hospitals is important. The importance arises because of the high prevalence of hypertension in this multicultural region. This study evaluated the use of antihypertensive medications among … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 8,312 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing the Applicability of Landslide Databases for Hazard Management Using Objective and Subjective Models: Australian Geoinformatic CaseM. OwneghProblem statement: In order to assess the applicability of Australian landslide databases as a hazard management support system, current hard and soft literature and data sources were screened. This assessment resulted in the selection of four main data bases including national landslide database (A), Peril Aus ІІ (B), the Cities project (C) and analytical study of Fell (D). Approach: In … …Current Research in Geoscience, Vol. 1, Issue 1 · 30 Jun 2010 · 10,352 accessesView PDFCite
Research ArticleOpen accessIn the abstractTarget Identification in Ory S1 Pollen Protein Allergen from Oryza sativa in the Course of Construction of Hypoallergenic VaccinesRuchi Sharma, A. K. SinghProblem statement: Recombinant-based approaches are mostly focused on genetic modification of allergens to produce molecules with reduced allergenic activity and conserved antigenicity, such as hypoallergens. Recombinant allergens represent promising tools for diagnosis and therapy of type I allergy. This approach was probably feasible with every allergen with known amino acid sequence. Approach: The primary aim of this study was to … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,438 accessesView PDFCite