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Research ArticleOpen accessIn the abstractProtective Effect of Enicostemma littorale Blume on Rat Model of Diabetic NeuropathyNiraj Mukundray Bhatt, Suparna Barua, Sarita GuptaProblem statement: Poor glycemic control and oxidative stress is implicated as a common pathway in the development of diabetic neuropathy. Approach: In the present study, we investigated the protective effects of Enicostemma littorale Blume (EL) (2.5 g kg-1), a hypoglycemic and antioxidant herbal medicine in alloxan-induced diabetic neuropathy in male Charles foster rats. Results: Tail flick latency in hot immersion … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 7,838 accessesView PDFCite
Research ArticleOpen accessIn the abstractVoltage-Gated Channels as Causative Agents for EpilepsiesMutasem Abuhamed, Xiao Bo, Kun Xia et al.Problem statement: Epilepsy is a common neurological disorder that afflicts 1-2% of the general population worldwide. It encompasses a variety of disorders with seizures. Approach: Idiopathic epilepsies were defined as a heterogeneous group of seizure disorders that show no underlying cause .Voltage-gated ion channels defect were recognized etiology of epilepsy in the central nervous system. The aim of this article … …American Journal of Immunology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,959 accessesView PDFCite
Research ArticleOpen accessIn the abstractFeatures in Tubercular Meningoencephalitis Diagnosis: 18 Childhood CasesP. Di Carlo, D. Cabibi, A. Casuccio et al.The aim of this research is to illustrate clinical and instrumental features of central nervous system tuberculosis (CNS-TB) in childhood in order to allow prompt diagnosis and adequate patient management. TB remains one of the most important communicable diseases and represents a major global health problem. Although pulmonary TB tends to be the most common form of the disease, the … …American Journal of Infectious Diseases, Vol. 4, Issue 3 · 30 Sep 2008 · 6,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpairment of Retrograde Neuronal Transport in Cardiac Vagal Motoneurons in Streptozotocin-Induced Diabetic Rats: A Wheat Ger Agglutinin-Horseradish Peroxidase Neurohistochemical studyA. Odekunle, C.M. PhillipsCentral projections of vagal motoneurons to the heart were studied in diabetic rats using Wheat germ Agglutinin-Horseradish peroxidase (WGA-HRP). Experimental rats were rendered diabetic by intraperitoneal injection of streptozotocin in citrate buffer. The diabetic rats were maintained in a stable diabetic state by daily injection of insulin for 24 weeks. Age-matched control rats were injected intraperitoneally with citrate buffer not … …OnLine Journal of Biological Sciences, Vol. 8, Issue 2 · 30 Jun 2008 · 6,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractBridging from Cells to Cognition in Autism Pathophysiology: Biological Pathways to Defective Brain Function and PlasticityMatthew P. Anderson, Brian S. Hooker, Martha R. HerbertWe review evidence to support a model where the disease process underlying autism may begin when an in utero or early postnatal environmental, infectious, seizure, or autoimmune insult triggers an immune response that increases reactive oxygen species (ROS) production in the brain that leads to DNA damage (nuclear and mitochondrial) and metabolic enzyme blockade and that these inflammatory and oxidative … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 17,455 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalysis of Speech Processing Strategies in Cochlear ImplantsKouachi Rouiha, Djedou Bachir, Bouchaala AliCochlear implants can restore partial hearing to profoundly deaf people; the main function of these prostheses is to electrically stimulate the auditory nerve using an electrode array inserted in the cochlea. The acoustic signal is picked up by a microphone and analyzed. Then the extracted parameters of the signal are coded to generate electrical signals reconstituting the original signal. Currently … …Journal of Computer Science, Vol. 4, Issue 5 · 31 May 2008 · 6,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Triggers for Intervention in Aging, Disease and TraumaJoan Smith SonnebornHormesis refers to the ability of a chemical or physical agent to condition the physiological state of an organism to tolerate stress with low doses of otherwise harmful agents. Evolutionary evidence shows that the survival and longevity of species hinge on their optimal ability to resist stress challenge. Hormesis is a potent strategy to stimulate latent repair processes to tolerate … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,895 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relationship Between Location and Prognosis in Brain-Stem TumorsN. Fayed, P. J. Modrego, J. EirasThe objective of this study was to establish a correlation between histopathology and radiological characteristics as well as location of brain stem tumors. Results of therapy were also analysed in relation to the radiological characteristics. Forty four patients were evaluated from a clinical and neuroradiological viewpoint (CT and MRI). In 14 of them we ruled out a surgical therapy. However … …OnLine Journal of Biological Sciences, Vol. 7, Issue 2 · 31 Dec 2007 · 6,839 accessesView PDFCite
Research ArticleOpen accessIn the abstractHIV-1 Infection and Central Monoamine NeurotransmittersAdarsh M. Kumar, J. B. Fernandez, Irina Borodowsky et al.Human immunodeficiency virus type 1 (HIV-1) enters the central nervous system (CNS) shortly after infection and gets localized in different brain regions, leading to various types of neuropathological problems. It has been hypothesized that HIV-1 infection mediated neuropathogenesis may also adversely affect the activity of the central monoamine neurotransmitters systems, such as dopamine (DA), and 5-hydroxytryptamine (5-HT, serotonin), resulting in … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,491 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Canadian Regulations and Remediation Methods for Diesel Oil Contaminated SoilsD. G. Rushton, A E. Ghaly, K. MartinellDiesel fuel released into the environment can contaminate ground water, degrade potable water supplies and cause the collapse of fisheries. They are toxic to both animals and humans and can affect the liver, lungs, kidneys, and nervous system leading to cancer as well as immunological and reproductive effects. The objectives of this study were to review current Canadian regulations pertaining … …American Journal of Applied Sciences, Vol. 4, Issue 7 · 31 Jul 2007 · 8,758 accessesView PDFCite