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159 results for “Fusion”
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Research ArticleOpen accessIn the abstractIs RNA Binding in the Rossmann Fold Essential for GAPDH Intranuclear Functions?Natalia Krynetskaia, Manali Phadke, Evgeny KrynetskiyIn addition to its prominent enzymatic activity, GAPDH is an enigmatic component of multiple unrelated biochemical entities. In this study, we explored a series of mutated GAPDH and fusion EGFP-GAPDH polypeptides and compared nuclear accumulation, intranuclear mobility and RNA binding properties of the wild type and variant GAPDH proteins. Our results revealed that RNA binding to T99I-mutated GAPDH with non-functional … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 14 Jun 2016 · 7,662 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeurophysiological Mechanisms of Rapidity Quality Development in Female Students Going in for Basketball and Volleyball at Sports ClubsAngelina Shakhanova, Aida Cheuzheva, Ekaterina Kalnaya, Tatiana PetrovaUsing the “NS-Pshykho Test” certified software package (Ivanovo, Russia), we studied the measurements of Simple Hand-Eye Response time (SHER), tapping test frequency, time of Reaction To Moving Object (RMO), Critical Flicker Fusion Frequency (CFFF) in female students going and not going in for sports (volleyball, basketball) at sports clubs. The basis of neuromotor state is formed by variants of classical … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 17 May 2016 · 7,608 accessesView PDFCite
Research ArticleOpen accessIn the abstractMolecular Characterization of Vaccine-Derived Mutants of Avian Metapneumoviruses Isolated from Turkeys in EgyptAbdel-Satar Arafa, Wessam Mady, Ahmed Hussein et al.Avian metapneumovirus (aMPV) causes acute respiratory infection in turkeys with sudden onset and rapid spread in the infected flocks. Vaccinated flocks frequently showed clinical signs typical like the non-vaccinated flocks in Egypt, this situation suggests a virulent vaccine virus was circulating in the field. Oropharyngeal and nasal sinus swabs were collected from 100 turkeys from 10 commercial farms with mild … …Current Research in Virology, Vol. 4, Issue 1 · 12 Aug 2015 · 12,754 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Proposed Integrated Human Recognition for Security ReassuranceZahraddeen Sufyanu, Fatma Susilawati Mohamad, Ahmad Salihu Ben-MusaA lot of systems require reliable and thorough authentication to ratify individual's claimed identity, especially in national and international security and defense. Unibiometric system suffers inherent weaknesses that are unavoidable in the system. Such inadequacies may directly or indirectly lead to an unacceptable error. For this reason, researchers pay great attention to the more advanced biometrics (referred to as multimodal … …American Journal of Applied Sciences, Vol. 12, Issue 2 · 11 Apr 2015 · 7,260 accessesView PDFCite
Research ArticleOpen accessIn the abstractDocking and Molecular Dynamics Simulations in Potential Drugs Discovery: An Application to Influenza Virus M2 ProteinMarine E. Bozdaganyan, Philipp S. Orekhov, Nicola L. Bragazzi et al.Molecular docking is a common method for searching new potential drugs. Improvement of the results of docking can be achieved by different ways-one of them is molecular dynamics simulations of protein-ligand complexes. As a model for our research we chose M2 membrane protein from influenza virus. M2 protein is a high selective tetrameric pH-gated proton channel. It was previously shown … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 11 Nov 2014 · 8,674 accessesView PDFCite
Research ArticleOpen accessIn the abstractMULTI SCALE TIME SERIES PREDICTION FOR INTRUSION DETECTIONG. Palanivel, K. DuraiswamyWe propose an anomaly-based network intrusion detection system, which analyzes traffic features to detect anomalies. The proposed system can be used both in online as well as off-line mode for detecting deviations from the expected behavior. Although our approach uses network packet or flow data, it is general enough to be adaptable for use with any other network variable, which … …American Journal of Applied Sciences, Vol. 11, Issue 8 · 27 Jun 2014 · 6,781 accessesView PDFCite
Research ArticleOpen accessIn the abstractA FRAMEWORK FOR MULTILINGUAL TEXT- INDEPENDENT SPEAKER IDENTIFICATION SYSTEMSundaradhas Selva Nidhyananthan, Ramapackiam Shantha Selva KumariThis article evaluates the performance of Extreme Learning Machine (ELM) and Gaussian Mixture Model (GMM) in the context of text independent Multi lingual speaker identification for recorded and synthesized speeches. The type and number of filters in the filter bank, number of samples in each frame of the speech signal and fusion of model scores play a vital role in … …Journal of Computer Science, Vol. 10, Issue 1 · 13 Nov 2013 · 7,279 accessesView PDFCite
Research ArticleOpen accessIn the abstractTRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES-AMAZING TOOL FOR GENOME EDITINGAvantika Singh, Vivek Pratap SinghTranscription Activator-Like Effector Nucleases (TALENs) are used to cut specific target DNA sequence in order to knock out a gene or to change its sequence. They are formed by the fusion of TALE protein serving as DNA binding domain along with non-specific DNA cleaving nucleases. Its specificity towards DNA bases in the target sequence is derived from the structure of … …OnLine Journal of Biological Sciences, Vol. 13, Issue 3 · 4 Sep 2013 · 8,000 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Immunogenicity of CP8, CLFA-FnBPB and CP8-CLFA-FnBPB AntigensXiuli Liu, Yongqing Hao, Shuyi Wang et al.To assess the effects of conjugating Capsular Polysaccharide (CP) with Clumping factor A (ClfA) and Fibronectin-Binding Proteins B (FnBPB) on the immunogenicity of the antigen, CP was isolated and purified from serotype 8 (CP8) Staphylococcus aureus from bovine mastitis dairy herds in Inner Mongolia and ClfA-FnBPB was produced with Escherichia coli encoding a fusion protein ClfA-FnBPB gene. The CP8-ClfA-FnBPB complete … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 30 Aug 2013 · 7,550 accessesView PDFCite