134 results for “ADR”

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Research ArticleOpen accessIn the abstractCardiovascular Effect of Capparis spinosa Aqueous Extract. Part VI: in vitro Vasorelaxant EffectN. A. Zeggwagh, J. B. Michel, M. EddouksThe aim of this study was to investigate the in vitro vasorelaxanteffect of Capparis spinosa aqueous extract (CSAE) at a dose of 10 mg mL-1. Aortic rings isolated from normal wistar rats were used. The addition of CSAE during the plateau phase of contraction, induced by noradrenaline and KCl, produced a rapid relaxation. Incubation of aortic ring with CSAE during … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,444 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNeuroendocrine Abnormalities in Drug Abusers and HIV-Infected Individuals: Cortisol Response to Cold Pressor ChallengeMahendra Kumar, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.Although endocrine abnormalities have been reported in HIV-1 infection, the role of risk factors is not understood. Injecting drug use (IDU) is an important risk factor for contracting HIV-infection and studies suggest that substance use may also be associated with endocrine dysfunction. In order to investigate hypothalamic pituitary adrenal (HPA) axis activity in this population, this study investigated cortisol response … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,594 accessesView PDF Cite

Research ArticleOpen accessIn the abstractCortisol Response Mediates HIV-1-Related Cognitive Deficits Among Injecting Drug AbusersRaymond L. Ownby, Drenna Waldrop-Valverde, Adarsh M. Kumar et al.The cortisol response is an important measure of the endocrine activity to environmental challenges and has been related to cognitive function and mood. Previous studies have shown that the cortisol response to stress is dysregulated in persons with HIV-1 infection. Since cortisol is neurotoxic and its levels have been related to cognitive dysfunction in various disorders, it is possible that … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,759 accessesView PDF Cite

Research ArticleOpen accessIn the abstractModelling the Effect of Salinity on the Multivariate Distribution of a Water Quality IndexDaniela cocchi, Michele scagliariniSalinity is a tracer of water and nutrient flows and is employed in studies on coastal environment to establish the coastal or remote origins of pollutants and nutrients. The present article analyses the effects of salinity on the multivariate distribution of the Trophic Index TRIX. The approach taken is based on a multivariate nested model with salinity as an explicative … …Journal of Mathematics and Statistics, Vol. 1, Issue 4 · 31 Dec 2005 · 5,915 accessesView PDF Cite